Related papers: Electron FLASH platform for pre-clinical research:…
A high peak current, flat longitudinal phase space electron beam is desirable for efficient x-ray free electron laser (FEL) radiation in next generation light sources. To attain such a beam requires the extensive design of the linear…
The linear accelerator (LINAC) at the Los Alamos Neu-tron Science Center (LANSCE) consists of Pre-buncher, Main-Buncher, low-energy beam transport (LEBT), four 201.25-MHz Drift Tube Linacs (DTLs) and forty-four 805-MHz Coupled Cavity Linacs…
X-ray photoelectron diffraction is a powerful tool for determining the structure of clean and adsorbate-covered surfaces. Extending the technique into the ultrafast time domain will open the door to studies as diverse as the direct…
Accurate control and monitoring of the beam is essential for precise dose delivery to tumor tissues during radiotherapy. Real-time monitoring of ion beam profiles and positions improves beam control, patient safety, and treatment…
Electrochemiluminescence (ECL) produces light through electrochemical reactions and has shown promise for various analytic applications in biomedicine. However, the use of ECL devices (ECLDs) as light sources has been limited due to…
Cancer therapy for deep-seated tumors requires precise irradiation of a small target deep within the patient while minimizing radiation exposure to surrounding tissues. This can be accomplished with a round beam sharply converging towards a…
Raman spectroscopy's capability to provide meaningful composition predictions is heavily reliant on a pre-processing step to remove insignificant spectral variation. This is crucial in biofluid analysis. Widespread adoption of diagnostics…
We conducted a multi-institutional audit of dosimetric variability between FLASH and conventional dose rate (CONV) electron irradiations by using an anatomically realistic 3D-printed mouse phantom. A CT scan of a live mouse was used to…
Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…
Background: FLASH radiation therapy (FLASH-RT) uses ultra-high dose rates to induce the FLASH effect, enhancing normal tissue sparing. In proton Bragg peak FLASH-RT, this effect is confined to high-dose regions near the target at deep…
Pulsed microwave stability in linear accelerators (LINACs) is critical for maintaining high-quality electron beams in synchrotron radiation and free-electron laser (FEL) facilities. This study establishes and validates a zero-crossing…
Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…
This letter proposes a new method based on ultrafast high energy electron radiography to diagnose transient electromagnetic field. For the traditional methods, large scattering from matter will increase the uncertainty of measurement, but…
In recent years, ultra-high dose rate (FLASH) radiotherapy has become a novel cancer treatment technique because of its similar tumor-killing efficacy as conventional particle therapy while significantly protecting normal tissues. However,…
Not long after the laser was invented, it has been marked as a candidate source of strong, high-frequency electromagnetic radiation for acceleration of particles. Indeed, while the complex particle accelerator facilities today are an…
Laser wakefield acceleration (LWFA) in a gas cell target separating injection and acceleration section has been investigated to produce high-quality electron beams. A detailed study has been performed on controlling the quality of…
Progress in optical techniques has made precision control of the phase profile in optical pulses common and accessible in scientific laboratories. Carefully shaping the field profile of a laser pulse can be used to master the dynamics of…
The design of the Linac Coherent Light Source assumes that a low-emittance, 1-nC, 10-ps beam will be available for injection into the 15-GeV linac. The proposed rf photocathode injector that will provide a 150-MeV beam with rms normalized…
We propose to use tightly focused lasers to generate high quality electron beams in laser wakefield accelerators. In this scheme, the expansion of the laser beam after the focal position enlarges the size of wakefield bubble, which reduces…
Controlling the intensity distribution of laser pulses in the focal region is essential for optimizing optically generated plasma waveguides and enabling advanced plasma acceleration techniques, including dephasingless wakefield…