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We present the design of a high repetition rate MeV energy ultrafast electron diffraction instrument based on a DC photoelectron gun and an SRF linac with multiple independently controlled accelerating and bunching cavities. The design is…

Accelerator Physics · Physics 2022-10-05 Adam Bartnik , Colwyn Gulliford , Georg H. Hoffstaetter , Jared Maxson

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…

This paper describes the dose delivery system used at the Centro Nazionale di Adroterapia Oncologica (CNAO) for ion beam modulated scanning radiotherapy. CNAO Foundation, INFN and University of Torino have developed and commissioned a Dose…

An optical injection scheme into the laser wakefield accelerator by preceding injection pulse is investigated by means of 3D numerical particle-in-cell simulations. Quasimonoenergetic hundred-pC electron bunches as short as 6 fs can be…

Plasma Physics · Physics 2020-03-06 Vojtěch Horný , Ondřej Klimo , Miroslav Krůs

Fetal ultrasound (US) examinations require the acquisition of multiple planes, each providing unique diagnostic information to evaluate fetal development and screening for congenital anomalies. However, obtaining a comprehensive,…

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

Chronic neck pain is a leading cause of disability worldwide, and current treatment selection remains largely trial and error. We present a machine learning framework that uses electroencephalography to predict treatment efficacy in…

Quantitative Methods · Quantitative Biology 2026-05-19 Xiru Wang , Aiden Li , Hongzhao Tan , Stevie Foglia , Aimee Nelson , Zhen Gao

Particle accelerators are essential tools in science, hospitals and industry. Yet, their costs and large footprint, ranging in length from meters to several kilometres, limit their use. The recently demonstrated nanophotonics-based…

Collinear high-gradient ${\cal O} (GV/m)$ beam-driven wakefield methods for charged-particle acceleration could be critical to the realization of compact, cost-efficient, accelerators, e.g., in support of TeV-scale lepton colliders or…

Accelerator Physics · Physics 2015-09-30 Francois Lemery , Philippe Piot

We present numerical simulations results on the injection and acceleration of a 10 MeV, 10 pC electrons beam in a plasma wave generated in a gas cell by a 2J, 45 fs laser beam. This modeling is related to the ESCULAP project in which the…

A method for the optimisation and advanced studies of a laser-plasma electron injector is presented, based on a truncated ionisation injection scheme for high quality beam production. The SMILEI code is used with laser envelope…

Generative models such as diffusion and flow matching have become dominant paradigms for visuomotor policy learning, yet their reliance on iterative denoising incurs high inference latency incompatible with real-time robotic control. We…

Robotics · Computer Science 2026-05-18 Jiaqi Bai , Jindou Jia , Yuxuan Hu , Gen Li , Xiangyu Chen , Tuo An , Kuangji Zuo , Jianfei Yang

Microfluidic fuel cells (MFCs) are microfluidic electrochemical conversion devices that are used to power small pieces of electrical equipment. Their performance relies on the improvement of the mass transfer of the reactants at the…

Patch-clamp technique is the gold standard for cellular electrophysiological measurements, which is capable of measuring single ion transport events across the cell membrane. However, the measurement possesses significant complexity, and it…

Instrumentation and Detectors · Physics 2021-01-21 Ali Aytac Seymen , Erol Ozgur , Zeliha Soran-Erdem , Bulend Ortac

Photoinjectors and Free Electron Lasers (FEL) are amongst the most advanced systems in accelerator physics and have consistently pushed the boundaries of emittance and x-ray peak power. In this paper, laser shaping at the cathode is…

Accelerator Physics · Physics 2023-06-30 Nicole Neveu , Randy Lemons , Joseph Duris , Jingyi Tang , Yuantao Ding , Agostino Marinelli , Sergio Carbajo

Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…

Medical Physics · Physics 2023-03-16 Sylvain Deffet , Kevin Souris , Edmond Sterpin

Injected beam energy and energy spread are critical parameters affecting the performance of our rapid cycling synchrotron (RCS). A real-time energy monitoring system is being installed to examine the H- beam out of the Intense Pulsed…

Accelerator Physics · Physics 2009-09-25 J. C. Dooling , F. R. Brumwell , M. K. Lien , G. E. McMichael

A device and a method for producing ultrashort electron pulses with GHz repetition rates via pulsing an input direct current (dc) electron beam are provided. The device and the method are based on an electromagnetic-mechanical pulser (EMMP)…

Instrumentation and Detectors · Physics 2015-08-18 Jiaqi Qiu , Gwanghui Ha , Chunguang Jing , Sergey V. Baryshev , Bryan W. Reed , Yimei Zhu , June W. Lau

The proposed Next Linear Collider (NLC) contains linac systems operating at L,S,C, and X band. This paper describes a wideband modular low-level RF (LLRF) system applicable for all NLC pulsed RF systems. High speed digital IF techniques are…

Accelerator Physics · Physics 2007-05-23 P. Corredoura , C. Adolphsen

The purpose of this study is to evaluate the clinical usefulness of modulated arc (mARC) treatment techniques. The mARC treatment plans of the non-small cell lung cancer (NSCLC) patients were performed in order to verify the clinical…

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