Related papers: Unveiling Parkinson's Disease-like Changes Trigger…
In this paper, by characterizing the Leg Agility (LA) task, which contributes to the evaluation of the degree of severity of the Parkinson's Disease (PD), through kinematic variables (including the angular amplitude and speed of thighs'…
Parkinson's disease (PD) is a progressive neurodegenerative disorder that results in a variety of motor dysfunction symptoms, including tremors, bradykinesia, rigidity and postural instability. The diagnosis of PD mainly relies on clinical…
Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…
Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…
Parkinson's disease (PD) is the most widespread movement condition and the second most common neurodegenerative disorder, following Alzheimer's. Movement symptoms and imaging techniques are the most popular ways to diagnose this disease.…
In this paper we evaluate the suitability of handwriting patterns as potential biomarkers to model Parkinson disease (PD). Although the study of PD is attracting the interest of many researchers around the world, databases to evaluate…
This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…
Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…
Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…
Parkinson's disease (PD), a prevalent neurodegenerative disorder, significantly affects patients' daily functioning and social interactions. To facilitate a more efficient and accessible diagnostic approach for PD, we propose a dynamic…
Parkinson's is a Neurologic disorder that not only affects the human body but also their social and personal life. Especially children having the Parkinson's disease come up with infinite difficulties in different areas of life mostly in…
People with Parkinson's Disease (PD) can slow the progression of their symptoms with physical therapy. However, clinicians lack insight into patients' motor function during daily life, preventing them from tailoring treatment protocols to…
Parkinson's disease (PD) shows heterogeneous, evolving brain-morphometry patterns. Modeling these longitudinal trajectories enables mechanistic insight, treatment development, and individualized 'digital-twin' forecasting. However, existing…
Many neurodegenerative diseases are related to the propagation and accumulation of toxic proteins throughout the brain. The lesions created by aggregates of these toxic proteins further lead to cell death and accelerated tissue atrophy. A…
Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…
Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…
Over the years motor deficit in Parkinson's Disease (PD) patients was largely studied, however, no consistent pattern of relations between quantitative electroencephalography (qEEG) and motor scales emerged. There is a general lack of…
Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…
Mobility is severely impacted in patients with Parkinson's disease (PD), especially when they experience involuntary stopping from the freezing of gait (FOG). Understanding the neurophysiological difference between "voluntary stopping" and…
At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…