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We present the Groupwise Diffusion Model (GDM), which divides data into multiple groups and diffuses one group at one time interval in the forward diffusion process. GDM generates data sequentially from one group at one time interval,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Sangyun Lee , Gayoung Lee , Hyunsu Kim , Junho Kim , Youngjung Uh

A generative modeling framework is proposed that combines diffusion models and manifold learning to efficiently sample data densities on manifolds. The approach utilizes Diffusion Maps to uncover possible low-dimensional underlying (latent)…

Machine Learning · Computer Science 2025-04-22 Dimitris G. Giovanis , Ellis Crabtree , Roger G. Ghanem , Ioannis G. Kevrekidis

Diffusion models (DMs) have revolutionized generative learning. They utilize a diffusion process to encode data into a simple Gaussian distribution. However, encoding a complex, potentially multimodal data distribution into a single…

Machine Learning · Computer Science 2024-07-04 Yilun Xu , Gabriele Corso , Tommi Jaakkola , Arash Vahdat , Karsten Kreis

The scale and quality of a dataset significantly impact the performance of deep models. However, acquiring large-scale annotated datasets is both a costly and time-consuming endeavor. To address this challenge, dataset expansion…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Haowei Zhu , Ling Yang , Jun-Hai Yong , Hongzhi Yin , Jiawei Jiang , Meng Xiao , Wentao Zhang , Bin Wang

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

We present TimeAutoDiff, a unified latent-diffusion framework for four fundamental time-series tasks: unconditional generation, missing-data imputation, forecasting, and time-varying-metadata conditional generation. The model natively…

Machine Learning · Computer Science 2025-12-09 Namjoon Suh , Yuning Yang , Din-Yin Hsieh , Qitong Luan , Shirong Xu , Shixiang Zhu , Guang Cheng

Accurate cell type annotation is a crucial step in analyzing single-cell RNA sequencing (scRNA-seq) data, which provides valuable insights into cellular heterogeneity. However, due to the high dimensionality and prevalence of zero elements…

Machine Learning · Computer Science 2025-08-14 Huifa Li , Jie Fu , Xinlin Zhuang , Haolin Yang , Xinpeng Ling , Tong Cheng , Haochen xue , Imran Razzak , Zhili Chen

In this paper, a novel semantic communication framework empowered by generative artificial intelligence (GAI) is proposed, to enhance the robustness against both channel noise and transmission data distribution shifts. A theoretical…

Machine Learning · Computer Science 2025-07-18 Xiucheng Wang , Honggang Jia , Nan Cheng

Recent advances in generative modeling, namely Diffusion models, have revolutionized generative modeling, enabling high-quality image generation tailored to user needs. This paper proposes a framework for the generative design of structural…

The life of a cell is governed by highly dynamical microscopic processes. Two notable examples are the diffusion of membrane receptors and the kinetics of transcription factors governing the rates of gene expression. Different fluorescence…

Quantitative Methods · Quantitative Biology 2020-04-03 Maxime Woringer , Ignacio Izeddin , Cyril Favard , Hugues Berry

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Diffusion models are the standard toolkit for generative modelling of 3D atomic systems. However, for different types of atomic systems -- such as molecules and materials -- the generative processes are usually highly specific to the target…

Variable selection for high-dimensional, highly correlated data has long been a challenging problem, often yielding unstable and unreliable models. We propose a resample-aggregate framework that exploits diffusion models' ability to…

Methodology · Statistics 2025-08-20 Minjie Wang , Xiaotong Shen , Wei Pan

Effectively addressing the challenge of industrial Anomaly Detection (AD) necessitates an ample supply of defective samples, a constraint often hindered by their scarcity in industrial contexts. This paper introduces a novel algorithm…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Hanxi Li , Zhengxun Zhang , Hao Chen , Lin Wu , Bo Li , Deyin Liu , Mingwen Wang

Diffusion models are a strong backbone for visual generation, but their inherently sequential denoising process leads to slow inference. Previous methods accelerate sampling by caching and reusing intermediate outputs based on feature…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Jiwoo Chung , Sangeek Hyun , MinKyu Lee , Byeongju Han , Geonho Cha , Dongyoon Wee , Youngjun Hong , Jae-Pil Heo

How to model distribution of sequential data, including but not limited to speech and human motions, is an important ongoing research problem. It has been demonstrated that model capacity can be significantly enhanced by introducing…

Machine Learning · Computer Science 2018-06-19 Guokun Lai , Bohan Li , Guoqing Zheng , Yiming Yang

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu

Extracting individual elements from music mixtures is a valuable tool for music production and practice. While neural networks optimized to mask or transform mixture spectrograms into the individual source(s) have been the leading approach,…

Sound · Computer Science 2025-11-26 Genís Plaja-Roglans , Yun-Ning Hung , Xavier Serra , Igor Pereira

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Jee Seok Yoon , Chenghao Zhang , Heung-Il Suk , Jia Guo , Xiaoxiao Li

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang