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In a number of tomographic applications, data cannot be fully acquired, resulting in a severely underdetermined image reconstruction. In such cases, conventional methods lead to reconstructions with significant artifacts. To overcome these…

Numerical Analysis · Mathematics 2023-06-21 Simon Göppel , Jürgen Frikel , Markus Haltmeier

A major challenge in computed tomography (CT) is to reduce X-ray dose to a low or even ultra-low level while maintaining the high quality of reconstructed images. We propose a new method for CT reconstruction that combines penalized…

Machine Learning · Statistics 2017-07-11 Xuehang Zheng , Zening Lu , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

Computed Tomography (CT) imposes risk on the patients due to its inherent X-ray radiation, stimulating the development of low-dose CT (LDCT) imaging methods. Lowering the radiation dose reduces the health risks but leads to noisier…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Obtaining accurate and reliable images from low-dose computed tomography (CT) is challenging. Regression convolutional neural network (CNN) models that are learned from training data are increasingly gaining attention in low-dose CT…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Il Yong Chun , Xuehang Zheng , Yong Long , Jeffrey A. Fessler

Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of sinogram or projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Bo Zhou , S. Kevin Zhou , James S. Duncan , Chi Liu

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Compressed Sensing (CS) significantly speeds up Magnetic Resonance Image (MRI) processing and achieves accurate MRI reconstruction from under-sampled k-space data. According to the current research, there are still several problems with…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Junpeng Tan , Chunmei Qing , Xiangmin Xu

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Lu Xu , Yuwei Zhang , Ying Liu , Daoye Wang , Mu Zhou , Jimmy Ren , Jingwei Wei , Zhaoxiang Ye

Low Dose CT Denoising research aims to reduce the risks of radiation exposure to patients. Recently researchers have used deep learning to denoise low dose CT images with promising results. However, approaches that use mean-squared-error…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Sepehr Ataei , Javad Alirezaie , Paul Babyn

In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Andreas Kofler , Markus Haltmeier , Tobias Schaeffter , Marc Kachelrieß , Marc Dewey , Christian Wald , Christoph Kolbitsch

Low-dose computed tomography (LDCT) is the standard modality for lung cancer screening, known for its low radiation dose but high noise levels. While existing literature focuses on denoising LDCT images, comparative research on simulating…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaying Liu , Anna Corti , Valentina D. A. Corino , Luca Mainardi

Computed tomography from a low radiation dose (LDCT) is challenging due to high noise in the projection data. Popular approaches for LDCT image reconstruction are two-stage methods, typically consisting of the filtered backprojection (FBP)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Tim Selig , Thomas März , Martin Storath , Andreas Weinmann

To reduce the x-ray dose in computerized tomography (CT), many constrained optimization approaches have been proposed aiming at minimizing a regularizing function that measures lack of consistency with some prior knowledge about the object…

Medical Physics · Physics 2017-04-05 Edgar Garduño , Gabor T. Herman

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Low Dose Computed Tomography (LDCT) has offered tremendous benefits in radiation restricted applications, but the quantum noise as resulted by the insufficient number of photons could potentially harm the diagnostic performance. Current…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Xin Yi , Paul Babyn

Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Hongki Lim , Il Yong Chun , Yuni K. Dewaraja , Jeffrey A. Fessler

With substantial public concerns on potential cancer risks and health hazards caused by the accumulated radiation exposure in medical imaging, reducing radiation dose in X-ray based medical imaging such as Computed Tomography Perfusion…

Image and Video Processing · Electrical Eng. & Systems 2019-10-21 Peng Liu , Ruogu Fang