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Numerous dual-energy CT (DECT) techniques have been developed in the past few decades. Dual-energy CT (DECT) statistical iterative reconstruction (SIR) has demonstrated its potential for reducing noise and increasing accuracy. Our lab…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Tao Ge , Maria Medrano , Rui Liao , David G. Politte , Jeffrey F. Williamson , Bruce R. Whiting , Joseph A. O'Sullivan

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

Low-dose computed tomography (LDCT) has become the technology of choice for diagnostic medical imaging, given its lower radiation dose compared to standard CT, despite increasing image noise and potentially affecting diagnostic accuracy. To…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Bin Wang , Fei Deng , Peifan Jiang , Shuang Wang , Xiao Han , Zhixuan Zhang

This paper focuses on the development of a space-variant regularization model for solving an under-determined linear inverse problem. The case study is a medical image reconstruction from few-view tomographic noisy data. The primary…

Image and Video Processing · Electrical Eng. & Systems 2024-04-29 Elena Morotti , Davide Evangelista , Andrea Sebastiani , Elena Loli Piccolomini

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

We observed that recent state-of-the-art results on single image human pose estimation were achieved by multi-stage Convolution Neural Networks (CNN). Notwithstanding the superior performance on static images, the application of these…

Computer Vision and Pattern Recognition · Computer Science 2018-03-12 Yue Luo , Jimmy Ren , Zhouxia Wang , Wenxiu Sun , Jinshan Pan , Jianbo Liu , Jiahao Pang , Liang Lin

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

Spectral computed tomography (CT) is an emerging technology capable of providing high chemical specificity, which is crucial for many applications such as detecting threats in luggage. This type of application requires both fast and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Wail Mustafa , Christian Kehl , Ulrik Lund Olsen , Søren Kimmer Schou Gregersen , David Malmgren-Hansen , Jan Kehres , Anders Bjorholm Dahl

Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

Image reconstruction from computed tomography (CT) measurement is a challenging statistical inverse problem since a high-dimensional conditional distribution needs to be estimated. Based on training data obtained from high-quality…

Image and Video Processing · Electrical Eng. & Systems 2020-06-12 Alexander Denker , Maximilian Schmidt , Johannes Leuschner , Peter Maass , Jens Behrmann

Numerous diffusion model (DM)-based methods have been proposed for solving inverse imaging problems. Among these, a recent line of work has demonstrated strong performance by formulating sampling as an optimization procedure that enforces…

Image and Video Processing · Electrical Eng. & Systems 2025-11-19 Shijun Liang , Ismail Alkhouri , Qing Qu , Rongrong Wang , Saiprasad Ravishankar

Low dose computed tomography is a mainstream for clinical applications. How-ever, compared to normal dose CT, in the low dose CT (LDCT) images, there are stronger noise and more artifacts which are obstacles for practical applications. In…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Dayang Wang , Zhan Wu , Hengyong Yu

A neural-network (NN)-based method for high-speed, high-definition dynamic optical coherence tomography (DOCT) using full-field swept-source optical coherence microscopy (FF-SS-OCM) is demonstrated. FF-SS-OCM provides high-definition OCT…

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

Optics · Physics 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

Restoring high-quality CT images from low dose CT counterparts is an ill-posed, nonlinear problem to which Deep Learning approaches have been giving superior solutions compared to classical model-based approaches. In this article, a…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Shabab Bazrafkan , Vincent Van Nieuwenhove , Jan Sijbers

We consider reconstructing multi-channel images from measurements performed by photon-counting and energy-discriminating detectors in the setting of multi-spectral X-ray computed tomography (CT). Our aim is to exploit the strong structural…

Numerical Analysis · Mathematics 2021-03-11 Lukas Kiefer , Stefania Petra , Martin Storath , Andreas Weinmann

We explore the use of the recently proposed "total nuclear variation" (TNV) as a regularizer for reconstructing multi-channel, spectral CT images. This convex penalty is a natural extension of the total variation (TV) to vector-valued…

Medical Physics · Physics 2015-06-23 David Rigie , Patrick La Riviere

In computed tomography (CT), the forward model consists of a linear Radon transform followed by an exponential nonlinearity based on the attenuation of light according to the Beer-Lambert Law. Conventional reconstruction often involves…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Sara Fridovich-Keil , Fabrizio Valdivia , Gordon Wetzstein , Benjamin Recht , Mahdi Soltanolkotabi

Statistical image reconstruction (SIR) methods have shown potential to substantially improve the image quality of low-dose X-ray computed tomography (CT) as compared to the conventional filtered back-projection (FBP) method for various…

Medical Physics · Physics 2015-05-15 Hao Zhang , Jing Wang , Jianhua Ma , Hongbing Lu , Zhengrong Liang

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Dongkyu Won , Euijin Jung , Sion An , Philip Chikontwe , Sang Hyun Park
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