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The joint implementation of federated learning (FL) and explainable artificial intelligence (XAI) could allow training models from distributed data and explaining their inner workings while preserving essential aspects of privacy. Toward…

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

A primary goal of computational phenotype research is to conduct medical diagnosis. In hospital, physicians rely on massive clinical data to make diagnosis decisions, among which laboratory tests are one of the most important resources.…

Artificial Intelligence · Computer Science 2017-11-20 Shiyue Zhang , Pengtao Xie , Dong Wang , Eric P. Xing

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Generative models trained on multi-institutional datasets can provide an enriched understanding through diverse data distributions. However, training the models on medical images is often challenging due to hospitals' reluctance to share…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Minjun Kim , Minjee Kim , Jinhoon Jeong

The performance of deep learning-based methods strongly relies on the number of datasets used for training. Many efforts have been made to increase the data in the medical image analysis field. However, unlike photography images, it is hard…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Pochuan Wang , Chen Shen , Holger R. Roth , Dong Yang , Daguang Xu , Masahiro Oda , Kazunari Misawa , Po-Ting Chen , Kao-Lang Liu , Wei-Chih Liao , Weichung Wang , Kensaku Mori

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Generative pretraining (the "GPT" in ChatGPT) enables language models to learn from vast amounts of internet text without human supervision. This approach has driven breakthroughs across AI by allowing deep neural networks to learn from…

Neurons and Cognition · Quantitative Biology 2025-09-23 Thomas Serre , Ellie Pavlick

The ambiguity of the decision-making process has been pointed out as the main obstacle to applying the deep learning-based method in a practical way in spite of its outstanding performance. Interpretability could guarantee the confidence of…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Hyebin Lee , Seong Tae Kim , Yong Man Ro

Explaining Deep Learning models is becoming increasingly important in the face of daily emerging multimodal models, particularly in safety-critical domains like medical imaging. However, the lack of detailed investigations into the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Anees Ur Rehman Hashmi , Dwarikanath Mahapatra , Mohammad Yaqub

Generative AI has made impressive strides in enabling users to create diverse and realistic visual content such as images, videos, and audio. However, training generative models on large centralized datasets can pose challenges in terms of…

Machine Learning · Computer Science 2025-10-03 Fiona Victoria Stanley Jothiraj , Afra Mashhadi

The ability to interpret machine learning model decisions is critical in such domains as healthcare, where trust in model predictions is as important as their accuracy. Inspired by the development of prototype parts-based deep neural…

Machine Learning · Computer Science 2026-03-06 Jacek Karolczak , Jerzy Stefanowski

Faithful explanations are essential for machine learning models in high-stakes applications. Inherently interpretable models are well-suited for these applications because they naturally provide faithful explanations by revealing their…

Machine Learning · Computer Science 2025-02-28 Chudi Zhong , Panyu Chen , Cynthia Rudin

Deep generative models produce data according to a learned representation, e.g. diffusion models, through a process of approximation computing possible samples. Approximation can be understood as reconstruction and the large datasets used…

Human-Computer Interaction · Computer Science 2023-09-25 Luís Arandas , Mick Grierson , Miguel Carvalhais

Joint machine learning models that allow synthesizing and classifying data often offer uneven performance between those tasks or are unstable to train. In this work, we depart from a set of empirical observations that indicate the…

Machine Learning · Computer Science 2023-04-06 Kamil Deja , Tomasz Trzcinski , Jakub M. Tomczak

The rapid advancement of Artificial Intelligence (AI) has catalyzed revolutionary changes across various sectors, notably in healthcare. In particular, generative AI-led by diffusion models and transformer architectures-has enabled…

As machine learning models become increasingly prevalent in medical diagnostics, the need for interpretability and transparency becomes paramount. The XAI Renaissance signifies a significant shift in the field, aiming to redefine the…

Machine Learning · Computer Science 2023-06-05 Sujith K Mandala

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

The high complexity of deep learning models is associated with the difficulty of explaining what evidence they recognize as correlating with specific disease labels. This information is critical for building trust in models and finding…

Image and Video Processing · Electrical Eng. & Systems 2023-04-21 Ricardo Bigolin Lanfredi , Joyce D. Schroeder , Clement Vachet , Tolga Tasdizen

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang
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