English
Related papers

Related papers: Instruction-Based Molecular Graph Generation with …

200 papers

Cooking recipes are one of the most readily available kinds of procedural text. They consist of natural language instructions that can be challenging to interpret. In this paper, we propose a model to identify relevant information from…

Computation and Language · Computer Science 2024-01-23 Aissatou Diallo , Antonis Bikakis , Luke Dickens , Anthony Hunter , Rob Miller

Unsupervised Multiplex Graph Learning (UMGL) aims to learn node representations on various edge types without manual labeling. However, existing research overlooks a key factor: the reliability of the graph structure. Real-world data often…

Machine Learning · Computer Science 2024-09-27 Zhixiang Shen , Shuo Wang , Zhao Kang

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu

Large Language Models (LLMs) have demonstrated remarkable generalization and instruction-following capabilities with instruction tuning. The advancements in LLMs and instruction tuning have led to the development of Large Vision-Language…

Machine Learning · Computer Science 2024-11-05 Jinyoung Park , Minseong Bae , Dohwan Ko , Hyunwoo J. Kim

Molecule inverse folding has been a long-standing challenge in chemistry and biology, with the potential to revolutionize drug discovery and material science. Despite specified models have been proposed for different small- or…

Artificial Intelligence · Computer Science 2024-05-30 Zhangyang Gao , Jue Wang , Cheng Tan , Lirong Wu , Yufei Huang , Siyuan Li , Zhirui Ye , Stan Z. Li

Constructing appropriate representations of molecules lies at the core of numerous tasks such as material science, chemistry and drug designs. Recent researches abstract molecules as attributed graphs and employ graph neural networks (GNN)…

Machine Learning · Computer Science 2021-07-29 Jianwen Chen , Shuangjia Zheng , Ying Song , Jiahua Rao , Yuedong Yang

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

The design of target-specific molecules such as small molecules, peptides, and antibodies is vital for biological research and drug discovery. Existing generative methods are restricted to single-domain molecules, failing to address…

Machine Learning · Computer Science 2025-05-27 Xiangzhe Kong , Zishen Zhang , Ziting Zhang , Rui Jiao , Jianzhu Ma , Wenbing Huang , Kai Liu , Yang Liu

We study how to generate molecule conformations (i.e., 3D structures) from a molecular graph. Traditional methods, such as molecular dynamics, sample conformations via computationally expensive simulations. Recently, machine learning…

Machine Learning · Computer Science 2021-04-01 Minkai Xu , Shitong Luo , Yoshua Bengio , Jian Peng , Jian Tang

Equivariant diffusion models have emerged as the prevailing approach for generating novel crystal materials due to their ability to leverage the physical symmetries of periodic material structures. However, current models do not effectively…

Machine Learning · Computer Science 2025-03-04 Kishalay Das , Subhojyoti Khastagir , Pawan Goyal , Seung-Cheol Lee , Satadeep Bhattacharjee , Niloy Ganguly

Generating novel active molecules for a given protein is an extremely challenging task for generative models that requires an understanding of the complex physical interactions between the molecule and its environment. In this paper, we…

Code generation is increasingly critical for real-world applications. Still, diffusion-based large language models continue to struggle with this demand. Unlike free-form text, code requires syntactic precision; even minor structural…

Computation and Language · Computer Science 2026-01-07 Yiming Zeng , Jinghan Cao , Zexin Li , Yiming Chen , Tao Ren , Zhuochun Li , Dawei Xiang , Xidong Wu , Shangqian Gao , Tingting Yu

We introduce the new task of generating Illustrated Instructions, i.e., visual instructions customized to a user's needs. We identify desiderata unique to this task, and formalize it through a suite of automatic and human evaluation…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Sachit Menon , Ishan Misra , Rohit Girdhar

Deep neural networks have enabled researchers to create powerful generalized frameworks, such as transformers, that can be used to solve well-studied problems in various application domains, such as text and image. However, such generalized…

Machine Learning · Computer Science 2025-02-12 Rudrajit Dawn , Madhusudan Ghosh , Partha Basuchowdhuri , Sudip Kumar Naskar

Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

Hit-like molecular generation with therapeutic potential is essential for target-specific drug discovery. However, the field lacks heterogeneous data and unified frameworks for integrating diverse molecular representations. To bridge this…

Computation and Language · Computer Science 2025-07-15 Hang Yuan , Chen Li , Wenjun Ma , Yuncheng Jiang

In light of the recent success of Graph Neural Networks (GNNs) and their ability to perform inference on complex data structures, many studies apply GNNs to the task of text classification. In most previous methods, a heterogeneous graph,…

Machine Learning · Computer Science 2024-10-29 Yassine Abbahaddou , Johannes F. Lutzeyer , Michalis Vazirgiannis

Graph-structured data jointly contain discrete topology and continuous geometry, which poses fundamental challenges for generative modeling due to heterogeneous distributions, incompatible noise dynamics, and the need for equivariant…

Machine Learning · Computer Science 2026-04-10 Rongjian Xu , Teng Pang , Zhiqiang Dong , Guoqiang Wu

The effective communication of procedural knowledge remains a significant challenge in natural language processing (NLP), as purely textual instructions often fail to convey complex physical actions and spatial relationships. We address…

Computation and Language · Computer Science 2025-05-23 Jing Bi , Pinxin Liu , Ali Vosoughi , Jiarui Wu , Jinxi He , Chenliang Xu

Text classification plays an important role in various downstream text-related tasks, such as sentiment analysis, fake news detection, and public opinion analysis. Recently, text classification based on Graph Neural Networks (GNNs) has made…

Computation and Language · Computer Science 2025-12-24 Zuo Wang , Ye Yuan
‹ Prev 1 3 4 5 6 7 10 Next ›