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Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…
Mitotic figure detection in histology images is a hard-to-define, yet clinically significant task, where labels are generated with pathologist interpretations and where there is no ``gold-standard'' independent ground-truth. However, it is…
The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…
Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…
In the complex landscape of hematologic samples such as peripheral blood or bone marrow, cell classification, delineating diverse populations into a hierarchical structure, presents profound challenges. This study presents LeukoGraph, a…
Graph-based representation approaches have been proven to be successful in the analysis of biomedical data, due to their capability of capturing intricate dependencies between biological entities, such as the spatial organization of…
Digital pathology plays a vital role across modern medicine, offering critical insights for disease diagnosis, prognosis, and treatment. However, histopathology images often contain artifacts introduced during slide preparation and…
Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across…
Generative models, especially Diffusion Models, have demonstrated remarkable capability in generating high-quality synthetic data, including medical images. However, traditional class-conditioned generative models often struggle to generate…
Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques…
Cephalometric landmark detection is essential for orthodontic diagnostics and treatment planning. Nevertheless, the scarcity of samples in data collection and the extensive effort required for manual annotation have significantly impeded…
Precise segmentation and classification of cell instances are vital for analyzing the tissue microenvironment in histology images, supporting medical diagnosis, prognosis, treatment planning, and studies of brain cytoarchitecture. However,…
White blood cells (WBCs) play a crucial role in safeguarding the human body against pathogens and foreign substances. Leveraging the abundance of WBC imaging data and the power of deep learning algorithms, automated WBC analysis has the…
Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…
Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…
Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…
Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…
Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…
3D spatial graphs play a crucial role in biological and clinical research by modeling anatomical networks such as blood vessels,neurons, and airways. However, generating 3D biological graphs while maintaining anatomical validity remains…
Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…