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Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Purpose: Coronary artery calcium (CAC) score, i.e. the amount of CAC quantified in CT, is a strong and independent predictor of coronary heart disease (CHD) events. However, CAC scoring suffers from limited interscan reproducibility, which…

Background and Objective: Breast cancer, which accounts for 23% of all cancers, is threatening the communities of developing countries because of poor awareness and treatment. Early diagnosis helps a lot in the treatment of the disease. The…

Prostate cancer is among the most common cancer in males and its heterogeneity is well known. Its early detection helps making therapeutic decision. There is no standard technique or procedure yet which is full-proof in predicting cancer…

Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to…

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies, even though randomized controlled trials are considered the…

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. Most colorectal cancers start as a growth on the inner lining of the colon or rectum, called 'polyp'. Not all polyps are cancerous, but…

Magnetic Resonance Imaging (MRI) is widely used for screening and staging prostate cancer. However, many prostate cancers have subtle features which are not easily identifiable on MRI, resulting in missed diagnoses and alarming variability…

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

Cancer results from genetic alterations that disturb the normal cooperative behavior of cells. Recent high-throughput genomic studies of cancer cells have shown that the mutational landscape of cancer is complex and that individual cancers…

According to the data, the percent of women who underwent screening for cervical cancer, breast and oral cancer in Telangana in the year 2020 was 3.3 percent, 0.3 percent and 2.3 percent respectively. Although early detection is the only…

Colorectal cancer is a prevalent form of cancer, and many patients develop colorectal cancer liver metastasis (CRLM) as a result. Early detection of CRLM is critical for improving survival rates. Radiologists usually rely on a series of…

Diabetes, a pervasive and enduring health challenge, imposes significant global implications on health, financial healthcare systems, and societal well-being. This study undertakes a comprehensive exploration of various structural learning…

The Galleri (R) (GRAIL) multi-cancer early detection test measures circulating tumour DNA (ctDNA) to predict the presence of more than 50 different cancers, from a blood test. If sensitivity of the test to detect early-stage cancers is…

Cancer is increasingly a global health issue. Seconding cardiovascular diseases, cancers are the second biggest cause of death in the world with millions of people succumbing to the disease every year. According to the World Health…

Integrative analyses based on statistically relevant associations between genomics and a wealth of intermediary phenotypes (such as imaging) provide vital insights into their clinical relevance in terms of the disease mechanisms. Estimates…

Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased states must be…

Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States due to its five-year survival rate of 10%. Late diagnosis, affiliated with the asymptomatic nature in early stages and the location of the cancer with…

Ovarian cancer is the most lethal gynecologic malignancy: around 60% of patients are diagnosed at an advanced stage, with an associated 5-year survival rate of about 30%. Early identification of non-responders to neoadjuvant chemotherapy…