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Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

The chest X-rays (CXRs) is one of the views most commonly ordered by radiologists (NHS),which is critical for diagnosis of many different thoracic diseases. Accurately detecting thepresence of multiple diseases from CXRs is still a…

Computer Vision and Pattern Recognition · Computer Science 2020-05-27 Hieu H. Pham , Tung T. Le , Dat T. Ngo , Dat Q. Tran , Ha Q. Nguyen

With recent advancements in the development of artificial intelligence applications using theories and algorithms in machine learning, many accurate models can be created to train and predict on given datasets. With the realization of the…

Machine Learning · Computer Science 2024-03-29 Pei Xi , Lin

This study investigates the application of quantum neural networks (QNNs) for propensity score estimation to address selection bias in comparing survival outcomes between laparoscopic and open surgical techniques in a cohort of 1177…

Quantum Physics · Physics 2025-06-26 Vojtěch Novák , Ivan Zelinka , Lenka Přibylová , Lubomír Martínek

In epidemiological disease mapping one aims to estimate the spatio-temporal pattern in disease risk and identify high-risk clusters, allowing health interventions to be appropriately targeted. Bayesian spatio-temporal models are used to…

Methodology · Statistics 2014-11-11 Duncan Lee , Andrew Lawson

Colonoscopy is used for colorectal cancer (CRC) screening. Extracting details of the colonoscopy findings from free text in electronic health records (EHRs) can be used to determine patient risk for CRC and colorectal screening strategies.…

Computation and Language · Computer Science 2021-08-26 Shashank Reddy Vadyala , Eric A. Sherer

Colorectal cancer frequently metastasizes to the liver, significantly reducing long-term survival. While surgical resection is the only potentially curative treatment for colorectal liver metastasis (CRLM), patient outcomes vary widely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Muhammad Alberb , Helen Cheung , Anne Martel

In preoperative imaging, the demarcation of rectal cancer with magnetic resonance images provides an important basis for cancer staging and treatment planning. Recently, deep learning has greatly improved the state-of-the-art method in…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Joohyung Lee , Ji Eun Oh , Min Ju Kim , Bo Yun Hur , Dae Kyung Sohn

The long-term efficacy of targeted therapeutics for cancer treatment can be significantly limited by the type of therapy and development of drug resistance, inter alia. Experimental studies indicate that the factors enhancing acquisition of…

Tissues and Organs · Quantitative Biology 2021-02-16 Joseph Malinzi , Kevin Bosire Basita , Sara Padidar , Henry A. Adeola

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

Computation · Statistics 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

The rapid growth of e-commerce has made people accustomed to shopping online. Before making purchases on e-commerce websites, most consumers tend to rely on rating scores and review information to make purchase decisions. With this…

Information Retrieval · Computer Science 2020-07-07 Yingqiang Ge , Shuyuan Xu , Shuchang Liu , Zuohui Fu , Fei Sun , Yongfeng Zhang

Community detection involves grouping the nodes in the network and is one of the most-studied tasks in network science. Conventional methods usually require the specification of the number of communities $K$ in the network. This number is…

Methodology · Statistics 2025-09-30 Yuhua Zhang , Kori S. Zachrison , Renee Y. Hsia , Jukka-Pekka Onnela

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…

Artificial Intelligence · Computer Science 2024-04-18 Nantika Nguycharoen

Respondent-driven sampling (RDS) is a popular method for sampling hard-to-survey populations that leverages social network connections through peer recruitment. While RDS is most frequently applied to estimate the prevalence of infections…

Methodology · Statistics 2016-10-24 Ashton M. Verdery , Jacob C. Fisher , Nalyn Siripong , Kahina Abdesselam , Shawn Bauldry

Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Christiaan G. A. Viviers , Mark Ramaekers , Peter H. N. de With , Dimitrios Mavroeidis , Joost Nederend , Misha Luyer , Fons van der Sommen

Cancer progression is an evolutionary process that is driven by mutation and selection in a population of tumor cells. We discuss mathematical models of cancer progression, starting from traditional multistage theory. Each stage is…

Populations and Evolution · Quantitative Biology 2011-08-31 Moritz Gerstung , Niko Beerenwinkel

Cancer development is a multistep process often starting with a single cell in which a number of epigenetic and genetic alterations have accumulated thus transforming it into a tumor cell. The progeny of such a single benign tumor cell…

Tissues and Organs · Quantitative Biology 2022-09-21 Steffen Lange , Richard Mogwitz , Denis Hünniger , Anja Voss-Böhme

In this paper we use Bayesian networks to determine and visualise the interactions among various Class III malocclusion maxillofacial features during growth and treatment. We start from a sample of 143 patients characterised through a…

Applications · Statistics 2018-01-24 Marco Scutari , Pietro Auconi , Guido Caldarelli , Lorenzo Franchi

Uncertainty quantification is necessary for developers, physicians, and regulatory agencies to build trust in machine learning predictors and improve patient care. Beyond measuring uncertainty, it is crucial to express it in clinically…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jacopo Teneggi , J Webster Stayman , Jeremias Sulam
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