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Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a…

Image and Video Processing · Electrical Eng. & Systems 2023-01-13 Siteng Chen , Xiyue Wang , Jun Zhang , Liren Jiang , Ning Zhang , Feng Gao , Wei Yang , Jinxi Xiang , Sen Yang , Junhua Zheng , Xiao Han

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

Strategies to prevent cancer and diagnose it early when it is most treatable are needed to reduce the public health burden from rising disease incidence. Risk assessment is playing an increasingly important role in targeting individuals in…

Applications · Statistics 2020-03-09 Adam R Brentnall , Jack Cuzick

Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…

Machine Learning · Computer Science 2025-11-20 Zisong Wang , Xuanyu Wang , Hang Chen , Haizhou Wang , Yuxin Chen , Yihang Xu , Yunhe Yuan , Lihuan Luo , Xitong Ling , Xiaoping Liu

Purpose: Health recommenders act as important decision support systems, aiding patients and medical professionals in taking actions that lead to patients' well-being. These systems extract the information which may be of particular…

Machine Learning · Computer Science 2024-07-02 Abhishek Dey , Debayan Goswami , Rahul Roy , Susmita Ghosh , Yu Shrike Zhang , Jonathan H. Chan

Survival prediction aims to evaluate the risk level of cancer patients. Existing methods primarily rely on pathology and genomics data, either individually or in combination. From the perspective of cancer pathogenesis, epigenetic changes,…

Machine Learning · Computer Science 2025-06-23 Haipeng Zhou , Sicheng Yang , Sihan Yang , Jing Qin , Lei Chen , Lei Zhu

Dealing with the application of grading colorectal cancer images, this work proposes a 3 step pipeline for prediction of cancer levels from a histopathology image. The overall model performs better compared to other state of the art methods…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Franziska Lippoldt

Background: Radiotherapy outcomes are usually predicted using the Linear Quadratic model. However, this model does not integrate complex features of tumor growth, in particular cell cycle regulation. Methods: In this paper, we propose a…

Tissues and Organs · Quantitative Biology 2007-05-23 Benjamin Ribba , Thierry Colin , Santiago Schnell

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

The liver is the most involved organ by distant metastasis in colon-rectal cancer (CRC) patients and it comes necessary to be aware of the mutational status of the lesions to correctly design the best individual treatment. So far, efforts…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Daniele Perlo , Luca Berton , Alessia Delpiano , Francesca Menchini , Stefano Tibaldi , Marco Grosso , Paolo Fonio

Cancers are the leading cause of death in many countries. Early diagnosis plays a crucial role in having proper treatment for this debilitating disease. The automated classification of the type of cancer is a challenging task since…

Image and Video Processing · Electrical Eng. & Systems 2021-08-20 Hosein Barzekar , Zeyun Yu

Traditional causal inference approaches leverage observational study data to estimate the difference in observed and unobserved outcomes for a potential treatment, known as the Conditional Average Treatment Effect (CATE). However, CATE…

Machine Learning · Statistics 2022-09-22 Tianhui Zhou , William E Carson , David Carlson

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model)…

Colorectal Cancer(CRC) poses a great risk to public health. It is the third most common cause of cancer in the US. Development of colorectal polyps is one of the earliest signs of cancer. Early detection and resection of polyps can greatly…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Debayan Bhattacharya , Christian Betz , Dennis Eggert , Alexander Schlaefer

Colorectal cancers are the third most common type of cancer. They originate from intestinal crypts, glands that descend from the intestinal lumen into the underlying connective tissue. Normal crypts are thought to exist in a dynamic…

Tissues and Organs · Quantitative Biology 2015-06-17 Alexander G. Fletcher , Philip J. Murray , Philip K. Maini

Colorectal cancer (CRC) is highly heterogeneous, with five-year survival rates dropping from $\sim$90% in localized disease to $\sim$15% with distant metastases. Disease progression is shaped not only by tumor-intrinsic alterations but also…

Breast cancer is the most common malignancy affecting women worldwide and is notable for its morphologic and biologic diversity, with varying risks of recurrence following treatment. The Oncotype DX Breast Recurrence Score test is an…

Chest radiography is one of the most common types of diagnostic radiology exams, which is critical for screening and diagnosis of many different thoracic diseases. Specialized algorithms have been developed to detect several specific…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Hieu H. Pham , Tung T. Le , Dat Q. Tran , Dat T. Ngo , Ha Q. Nguyen

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

In this work, we investigate the importance of ethnicity in colorectal cancer survivability prediction using machine learning techniques and the SEER cancer incidence database. We compare model performances for 2-year survivability…

Machine Learning · Computer Science 2019-01-15 Samuel Li , Talayeh Razzaghi