Related papers: Discriminating retinal microvascular and neuronal …
Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…
Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…
The optic nerve head (ONH) typically experiences complex neural- and connective-tissue structural changes with the development and progression of glaucoma, and monitoring these changes could be critical for improved diagnosis and prognosis…
The ultra-widefield (UWF) fundus image is an attractive 3D biomarker in AI-aided myopia screening because it provides much richer myopia-related information. Though axial length (AL) has been acknowledged to be highly related to the two key…
Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…
Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations.…
Accurate detection of retinal vessels plays a critical role in reflecting a wide range of health status indicators in the clinical diagnosis of ocular diseases. Recently, advances in deep learning have led to a surge in retinal vessel…
Deep learning has potential to automate screening, monitoring and grading of disease in medical images. Pretraining with contrastive learning enables models to extract robust and generalisable features from natural image datasets,…
Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…
We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal…
Visual field tests (VFT) are pivotal for glaucoma diagnosis and conducted regularly to monitor disease progression. Here we address the question to what degree aggregate VFT measurements such as Visual Field Index (VFI) and Mean Deviation…
The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…
Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…
The Convolutional Neural Network (CNN) has shown impressive performance in image classification because of its strong learning capabilities. However, it demands a substantial and balanced dataset for effective training. Otherwise, networks…
In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…
Purpose: Microaneurysms (MAs) have distinct, oval-shaped, hyperreflective walls on structural OCT, and inconsistent flow signal in the lumen with OCT angiography (OCTA). Their relationship to regional macular edema in diabetic retinopathy…
Deep convolutional neural networks (DCNNs) and the ventral visual pathway share vast architectural and functional similarities in visual challenges such as object recognition. Recent insights have demonstrated that both hierarchical…
Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…
Purpose: To identify ocular hypertension (OHT) subtypes with different trends of visual field (VF) progression based on unsupervised machine learning and to discover factors associated with fast VF progression. Participants: A total of 3133…
Humans actively observe the visual surroundings by focusing on salient objects and ignoring trivial details. However, computer vision models based on convolutional neural networks (CNN) often analyze visual input all at once through a…