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Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yiqian Wang , Alexandra Warter , Melina Cavichini , Varsha Alex , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for…

Medical Physics · Physics 2020-06-02 Ce Zheng , Xiaolin Xie , Kang Zhou , Bang Chen , Jili Chen , Haiyun Ye , Wen Li , Tong Qiao , Shenghua Gao , Jianlong Yang , Jiang Liu

Deep neural networks (DNNs) have proven to be successful in various computer vision applications such that models even infer in safety-critical situations. Therefore, vision models have to behave in a robust way to disturbances such as…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Patrick Müller , Alexander Braun , Margret Keuper

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zhun Fan , Jiajie Mo , Benzhang Qiu , Wenji Li , Guijie Zhu , Chong Li , Jianye Hu , Yibiao Rong , Xinjian Chen

Purpose: To quantify choriocapillaris flow alterations in early Sorsby Fundus Dystrophy (SFD) and to investigate the relationship of choriocapillaris flow with the choroidal and outer retinal microstructure. Methods: In this prospective…

The segmentation of retinal vessels is of significance for doctors to diagnose the fundus diseases. However, existing methods have various problems in the segmentation of the retinal vessels, such as insufficient segmentation of retinal…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Yun Jiang , Ning Tan

Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Muyi Sun , Guanhong Zhang

Diffractive deep neural networks have been introduced earlier as an optical machine learning framework that uses task-specific diffractive surfaces designed by deep learning to all-optically perform inference, achieving promising…

Neural and Evolutionary Computing · Computer Science 2019-08-14 Jingxi Li , Deniz Mengu , Yi Luo , Yair Rivenson , Aydogan Ozcan

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Mohammadreza Saraei , Igor Kozak , Eung-Joo Lee

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed…

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Qinghua He , Hongyang Jiang , Danqi Fang , Dawei Yang , Truong X. Nguyen , Anran Ran , Clement C. Tham , Simon K. H. Szeto , Sobha Sivaprasad , Carol Y. Cheung

This paper proposed a retinal image segmentation method based on conditional Generative Adversarial Network (cGAN) to segment optic disc. The proposed model consists of two successive networks: generator and discriminator. The generator…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Vivek Kumar Singh , Hatem Rashwan , Farhan Akram , Nidhi Pandey , Md. Mostaf Kamal Sarker , Adel Saleh , Saddam Abdulwahab , Najlaa Maaroof , Santiago Romani , Domenec Puig

This paper experiments with the number of fully-connected layers in a deep convolutional neural network as applied to the classification of fundus retinal images. The images analysed corresponded to the ODIR 2019 (Peking University…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Ajna Ram , Constantino Carlos Reyes-Aldasoro

This study is to characterize reflectance profiles of retinal blood vessels in optical coherence tomography (OCT), and to validate these vascular features to guide artery-vein classification in OCT angiography (OCTA) of human retina.…

Tissues and Organs · Quantitative Biology 2022-02-08 Tobiloba Adejumo , Tae-Hoon Kim , David Le , Taeyoon Son , Guangying Ma , Xincheng Yao

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

Retinal imaging is a critical, non-invasive modality for the early detection and monitoring of ocular and systemic diseases. Deep learning, particularly convolutional neural networks (CNNs), has significant progress in automated retinal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Xin Li , Wenhui Zhu , Xuanzhao Dong , Hao Wang , Yujian Xiong , Oana Dumitrascu , Yalin Wang
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