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Physics-based simulation is essential for developing and evaluating robot manipulation policies, particularly in scenarios involving deformable objects and complex contact interactions. However, existing simulators often struggle to balance…

Traditional robotic mechanisms contain a series of rigid links connected by rotational joints that provide powered motion, all of which is controlled by a central processor. By contrast, analogous mechanisms found in nature, such as octopus…

Computational Engineering, Finance, and Science · Computer Science 2023-11-06 Anurag Bhattacharyya , Jin-Young Kim , Lee R. Alacoque , Kai A. James

Active polymers are driven out of equilibrium by internal forces and exhibit conformational properties that differ fundamentally from those of passive chains. Here we study how spatially modulated tangential activity reshapes the…

Soft Condensed Matter · Physics 2025-12-17 Paolo Malgaretti , Emanuele Locatelli

Intracellular protein patterns govern essential cellular functions by dynamically redistributing proteins between membrane-bound and cytosolic states, conserving their total numbers. This review presents a theoretical framework for…

Biological Physics · Physics 2025-12-16 Erwin Frey , Henrik Weyer

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

Interactions between active individuals in animal collectives lead to emergent responses that remain elusive in synthetic soft matter. Here, shape-morphing polymers are used to create bio-inspired transient solids that self-assemble with…

Since the 1950s, soft ionic devices have evolved from individual components to an expanding library of sensors, actuators, signal transmitters, and processors. However, integrating these components into complex, multi-functional systems…

Soft Condensed Matter · Physics 2024-10-17 Max Tepermeister , Meredith N. Silberstein

There is a growing need for robots that can change their shape, size and mechanical properties to adapt to evolving tasks and environments. However, current shape-changing systems generally utilize bespoke, system-specific mechanisms that…

Robotics · Computer Science 2026-04-24 Niklas Hagemann , Daniela Rus

Robustness, the ability of a system to maintain performance under significant and unanticipated environmental changes, is a critical property for robotic systems. While biological systems naturally exhibit robustness, there is no…

Robotics · Computer Science 2024-08-20 Xing Li , Oussama Zenkri , Adrian Pfisterer , Oliver Brock

We study the yielding transition of a two dimensional amorphous system under shear by using a mesoscopic elasto-plastic model. The model combines a full (tensorial) description of the elastic interactions in the system, and the possibility…

Materials Science · Physics 2017-08-23 E. A. Jagla

This paper presents a modeling framework---mathematical model and computational framework---to study the response of a plastic material due to the presence and transport of a chemical species in the host material. Such a modeling framework…

Numerical Analysis · Mathematics 2020-11-16 M. S. Joshaghani , K. B. Nakshatrala

Morphogenesis, the establishment and repair of emergent complex anatomy by groups of cells, is a fascinating and biomedically-relevant problem. One of its most fascinating aspects is that a developing embryo can reliably recover from…

Molecular Networks · Quantitative Biology 2022-11-03 Joel Grodstein , Michael Levin

The cell cortex, a thin film of active material assembled below the cell membrane, plays a key role in cellular symmetry breaking processes such as cell polarity establishment and cell division. Here, we present a minimal model of the…

Biological Physics · Physics 2019-09-30 Alexander Mietke , V. Jemseena , K. Vijay Kumar , Ivo F. Sbalzarini , Frank Jülicher

Unlike other tissue types, like epithelial tissue, which consist of cells with a much more homogeneous structure and function, the nervous tissue spans in a complex multilayer environment whose topographical features display a large…

Biological Physics · Physics 2017-05-12 C. Simitzi , A. Ranella , E. Stratakis

Natural organisms can convert environmental stimuli into sensory feedback to regulate their body and realize active adaptivity. However, realizing such a feedback-regulation mechanism in synthetic material systems remains a grand challenge.…

Robotics · Computer Science 2024-12-23 Jianfeng Yang , Haotian Pi , Zixuan Deng , Hongshuang Guo , Wan Shou , Hang Zhang , Hao Zeng

Developing reliable mechanisms for continuous local learning is a central challenge faced by biological and artificial systems. Yet, how the environmental factors and structural constraints on the learning network influence the optimal…

Neurons and Cognition · Quantitative Biology 2024-03-21 Emmanouil Giannakakis , Sina Khajehabdollahi , Anna Levina

This paper proposes a methodology to extract a low-dimensional integrate-and-fire model from an arbitrarily detailed single-compartment biophysical model. The method aims at relating the modulation of maximal conductance parameters in the…

Neurons and Cognition · Quantitative Biology 2020-09-29 Tomas Van Pottelbergh , Guillaume Drion , Rodolphe Sepulchre

Cortical circuits are characterized by exquisitely complex connectivity patterns that emerge during development from undifferentiated networks. The development of these circuits is governed by a combination of precise molecular cues that…

Neurons and Cognition · Quantitative Biology 2020-09-15 Joseph Olson , Gabriel Kreiman

This study aims at finding a method for constructing molecular dynamics like models using the formalism of cellular automata for fast simulation of fluid dynamic systems (including compressible phenomena). In as much as the results…

comp-gas · Physics 2009-09-25 Himanshu Agrawal

Local patterns of excitation and inhibition that can generate neural waves are studied as a computational mechanism underlying the organization of neuronal tunings. Sparse coding algorithms based on networks of excitatory and inhibitory…

Neurons and Cognition · Quantitative Biology 2022-05-30 Leon Lufkin , Ashish Puri , Ganlin Song , Xinyi Zhong , John Lafferty