From biophysical to integrate-and-fire modelling
Neurons and Cognition
2020-09-29 v2
Abstract
This paper proposes a methodology to extract a low-dimensional integrate-and-fire model from an arbitrarily detailed single-compartment biophysical model. The method aims at relating the modulation of maximal conductance parameters in the biophysical model to the modulation of parameters in the proposed integrate-and-fire model. The approach is illustrated on two well-documented examples of cellular neuromodulation: the transition between Type I and Type II excitability and the transition between spiking and bursting.
Keywords
Cite
@article{arxiv.2006.10113,
title = {From biophysical to integrate-and-fire modelling},
author = {Tomas Van Pottelbergh and Guillaume Drion and Rodolphe Sepulchre},
journal= {arXiv preprint arXiv:2006.10113},
year = {2020}
}
Comments
This is the authors' final version. The article has been accepted for publication in Neural Computation