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Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Purpose: To investigate feasibility of accelerating prostate diffusion-weighted imaging (DWI) by reducing the number of acquired averages and denoising the resulting image using a proposed guided denoising convolutional neural network…

Image and Video Processing · Electrical Eng. & Systems 2020-07-02 Elena A. Kaye , Emily A. Aherne , Cihan Duzgol , Ida Häggström , Erich Kobler , Yousef Mazaheri , Maggie M Fung , Zhigang Zhang , Ricardo Otazo , Herbert A. Vargas , Oguz Akin

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Unsupervised domain adaptation (UDA) aims to improve the prediction performance in the target domain under distribution shifts from the source domain. The key principle of UDA is to minimize the divergence between the source and the target…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 JoonHo Lee , Gyemin Lee

The development of reliable and fair diagnostic systems is often constrained by the scarcity of labeled data. To address this challenge, our work explores the feasibility of unsupervised domain adaptation (UDA) to integrate large external…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Janet Wang , Yunbei Zhang , Zhengming Ding , Jihun Hamm

While Unsupervised Domain Adaptation (UDA) algorithms, i.e., there are only labeled data from source domains, have been actively studied in recent years, most algorithms and theoretical results focus on Single-source Unsupervised Domain…

Machine Learning · Computer Science 2022-01-05 Yongchun Zhu , Fuzhen Zhuang , Deqing Wang

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Unsupervised anomaly detection (UAD) learns one-class classifiers exclusively with normal (i.e., healthy) images to detect any abnormal (i.e., unhealthy) samples that do not conform to the expected normal patterns. UAD has two main…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Yu Tian , Guansong Pang , Fengbei Liu , Yuanhong chen , Seon Ho Shin , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Prostate Cancer (PCa) is a prevalent disease among men, and multi-parametric MRIs offer a non-invasive method for its detection. While MRI-based deep learning solutions have shown promise in supporting PCa diagnosis, acquiring sufficient…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Meng Zhou , Amoon Jamzad , Jason Izard , Alexandre Menard , Robert Siemens , Parvin Mousavi

Traditional deep learning (DL) approaches based on supervised learning paradigms require large amounts of annotated data that are rarely available in the medical domain. Unsupervised Out-of-distribution (OOD) detection is an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Alvaro Fernandez-Quilez , Linas Vidziunas , Ørjan Kløvfjell Thoresen , Ketil Oppedal , Svein Reidar Kjosavik , Trygve Eftestøl

Prostate biopsy and image-guided treatment procedures are often performed under the guidance of ultrasound fused with magnetic resonance images (MRI). Accurate image fusion relies on accurate segmentation of the prostate on ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Sulaiman Vesal , Iani Gayo , Indrani Bhattacharya , Shyam Natarajan , Leonard S. Marks , Dean C Barratt , Richard E. Fan , Yipeng Hu , Geoffrey A. Sonn , Mirabela Rusu

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

Low-dose computed tomography (LDCT) image reconstruction techniques can reduce patient radiation exposure while maintaining acceptable imaging quality. Deep learning is widely used in this problem, but the performance of testing data…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Kecheng Chen , Jie Liu , Renjie Wan , Victor Ho-Fun Lee , Varut Vardhanabhuti , Hong Yan , Haoliang Li

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-26 Yifan Zhang , Ying Wei , Qingyao Wu , Peilin Zhao , Shuaicheng Niu , Junzhou Huang , Mingkui Tan

The scarcity and complexity of voxel-level annotations in 3D medical imaging present significant challenges, particularly due to the domain gap between labeled datasets from well-resourced centers and unlabeled datasets from less-resourced…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Haifan Gong , Yitao Wang , Yihan Wang , Jiashun Xiao , Xiang Wan , Haofeng Li

We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Shaheer U. Saeed , Tom Syer , Wen Yan , Qianye Yang , Mark Emberton , Shonit Punwani , Matthew J. Clarkson , Dean C. Barratt , Yipeng Hu
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