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Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Data from a multi-parametric MRI study of patients with possible early-stage prostate cancer was assessed with a view to creating an efficient clinical protocol. Based on a correlation analysis suggesting that diffusion-weighted imaging…

Medical Physics · Physics 2017-11-28 Ioannis Papadopoulos , Jonathan Phillips , Rhodri Evans , Neil Fenn , Sophie Schermer

Unsupervised Domain Adaptation (UDA) is quite challenging due to the large distribution discrepancy between the source domain and the target domain. Inspired by diffusion models which have strong capability to gradually convert data…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Duo Peng , Qiuhong Ke , Yinjie Lei , Jun Liu

Unsupervised Domain Adaptation (UDA) refers to the problem of learning a model in a target domain where labeled data are not available by leveraging information from annotated data in a source domain. Most deep UDA approaches operate in a…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Massimiliano Mancini , Lorenzo Porzi , Samuel Rota Bulò , Barbara Caputo , Elisa Ricci

The Gleason grading system using histological images is the most powerful diagnostic and prognostic predictor of prostate cancer. The current standard inspection is evaluating Gleason H&E-stained histopathology images by pathologists.…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Haotian Xie , Yong Zhang , Jun Wang , Jingjing Zhang , Yifan Ma , Zhaogang Yang

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

Unsupervised domain adaptation (UDA) aims to transfer and adapt knowledge from a labeled source domain to an unlabeled target domain. Traditionally, subspace-based methods form an important class of solutions to this problem. Despite their…

Machine Learning · Computer Science 2022-01-07 Kowshik Thopalli , Jayaraman J Thiagarajan , Rushil Anirudh , Pavan K Turaga

Traditional machine learning assumes that training and test sets are derived from the same distribution; however, this assumption does not always hold in practical applications. This distribution disparity can lead to severe performance…

Machine Learning · Computer Science 2025-02-18 Ahmad Chaddad , Yihang Wu , Yuchen Jiang , Ahmed Bouridane , Christian Desrosiers

Purpose: The aim of this study was to demonstrate the utility of unsupervised domain adaptation (UDA) in automated knee osteoarthritis (OA) phenotype classification using a small dataset (n=50). Materials and Methods: For this retrospective…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Junru Zhong , Yongcheng Yao , Donal G. Cahill , Fan Xiao , Siyue Li , Jack Lee , Kevin Ki-Wai Ho , Michael Tim-Yun Ong , James F. Griffith , Weitian Chen

Incorporating data-specific domain knowledge in deep networks explicitly can provide important cues beneficial for lesion detection and can mitigate the need for diverse heterogeneous datasets for learning robust detectors. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Manu Sheoran , Meghal Dani , Monika Sharma , Lovekesh Vig

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Deep learning has become the method of choice to tackle real-world problems in different domains, partly because of its ability to learn from data and achieve impressive performance on a wide range of applications. However, its success…

Computer Vision and Pattern Recognition · Computer Science 2022-08-17 Xiaofeng Liu , Chaehwa Yoo , Fangxu Xing , Hyejin Oh , Georges El Fakhri , Je-Won Kang , Jonghye Woo

Methods for unsupervised domain adaptation (UDA) help to improve the performance of deep neural networks on unseen domains without any labeled data. Especially in medical disciplines such as histopathology, this is crucial since large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Kevin Thandiackal , Luigi Piccinelli , Pushpak Pati , Orcun Goksel

Objective: Latent diffusion models (LDMs) could mitigate data scarcity challenges affecting machine learning development for medical image interpretation. The recent CCELLA LDM improved prostate cancer detection performance using synthetic…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Emerson P. Grabke , Babak Taati , Masoom A. Haider

The segmentation of prostate whole gland and transition zone in Diffusion Weighted MRI (DWI) are the first step in designing computer-aided detection algorithms for prostate cancer. However, variations in MRI acquisition parameters and…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Saman Motamed , Isha Gujrathi , Dominik Deniffel , Anton Oentoro , Masoom A. Haider , Farzad Khalvati

Data augmentation (DA) is a key factor in medical image analysis, such as in prostate cancer (PCa) detection on magnetic resonance images. State-of-the-art computer-aided diagnosis systems still rely on simplistic spatial transformations to…

Domain shift happens in cross-domain scenarios commonly because of the wide gaps between different domains: when applying a deep learning model well-trained in one domain to another target domain, the model usually performs poorly. To…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Munan Ning , Cheng Bian , Dong Wei , Chenglang Yuan , Yaohua Wang , Yang Guo , Kai Ma , Yefeng Zheng

Unsupervised domain adaptation (UDA) for nuclei instance segmentation is important for digital pathology, as it alleviates the burden of labor-intensive annotation and domain shift across datasets. In this work, we propose a Cycle…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Dongnan Liu , Donghao Zhang , Yang Song , Fan Zhang , Lauren O'Donnell , Heng Huang , Mei Chen , Weidong Cai

Deep learning-based analysis of high-frequency, high-resolution micro-ultrasound data shows great promise for prostate cancer detection. Previous approaches to analysis of ultrasound data largely follow a supervised learning paradigm.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Paul F. R. Wilson , Mahdi Gilany , Amoon Jamzad , Fahimeh Fooladgar , Minh Nguyen Nhat To , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

Unsupervised domain adaptation (UDA) methods for learning domain invariant representations have achieved remarkable progress. However, most of the studies were based on direct adaptation from the source domain to the target domain and have…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Jaemin Na , Heechul Jung , Hyung Jin Chang , Wonjun Hwang