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The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

The recently proposed Segment Anything Model (SAM) is a general tool for image segmentation, but it requires additional adaptation and careful fine-tuning for medical image segmentation, especially for small, irregularly-shaped, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Yaxi Chen , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Background: We evaluate SAM 2 for surgical scene understanding by examining its semantic segmentation capabilities for organs/tissues both in zero-shot scenarios and after fine-tuning. Methods: We utilized five public datasets to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Devanish N. Kamtam , Joseph B. Shrager , Satya Deepya Malla , Xiaohan Wang , Nicole Lin , Juan J. Cardona , Serena Yeung-Levy , Clarence Hu

In this paper, we examine the recent Segment Anything Model (SAM) on medical images, and report both quantitative and qualitative zero-shot segmentation results on nine medical image segmentation benchmarks, covering various imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Peilun Shi , Jianing Qiu , Sai Mu Dalike Abaxi , Hao Wei , Frank P. -W. Lo , Wu Yuan

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Segment Anything Model (SAM) has demonstrated powerful zero-shot segmentation performance in natural scenes. The recently released Segment Anything Model 2 (SAM2) has further heightened researchers' expectations towards image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Jialun Pei , Zhangjun Zhou , Tiantian Zhang

Precision medicine, such as patient-adaptive treatments assisted by medical image analysis, poses new challenges for segmentation algorithms in adapting to new patients, due to the large variability across different patients and the limited…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Chenhui Zhao , Liyue Shen

Segment Anything Models (SAMs) like SEEM and SAM have demonstrated great potential in learning to segment anything. The core design of SAMs lies with Promptable Segmentation, which takes a handcrafted prompt as input and returns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Jiaxing Huang , Kai Jiang , Jingyi Zhang , Han Qiu , Lewei Lu , Shijian Lu , Eric Xing

The recent SAM 3 and SAM 3D have introduced significant advancements over the predecessor, SAM 2, particularly with the integration of language-based segmentation and enhanced 3D perception capabilities. SAM 3 supports zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Wenzhen Dong , Jieming Yu , Yiming Huang , Hongqiu Wang , Lei Zhu , Albert C. S. Chung , Hongliang Ren , Long Bai

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

Surgical video segmentation is critical for AI to interpret spatial-temporal dynamics in surgery, yet model performance is constrained by limited annotated data. The SAM2 model, pretrained on natural videos, offers potential for zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Cheng Yuan , Jian Jiang , Kunyi Yang , Lv Wu , Rui Wang , Zi Meng , Haonan Ping , Ziyu Xu , Yifan Zhou , Wanli Song , Hesheng Wang , Yueming Jin , Qi Dou , Yutong Ban

Background: The segment-anything model (SAM), introduced in April 2023, shows promise as a benchmark model and a universal solution to segment various natural images. It comes without previously-required re-training or fine-tuning specific…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Sheng He , Rina Bao , Jingpeng Li , Jeffrey Stout , Atle Bjornerud , P. Ellen Grant , Yangming Ou

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo