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The Segment Anything Model (SAM) is a recently developed large model for general-purpose segmentation for computer vision tasks. SAM was trained using 11 million images with over 1 billion masks and can produce segmentation results for a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Yizhe Zhang , Tao Zhou , Shuo Wang , Peixian Liang , Danny Z. Chen

Sharpness-aware minimization (SAM) seeks the minima with a flat loss landscape to improve the generalization performance in machine learning tasks, including fine-tuning. However, its extra parameter perturbation step doubles the…

Machine Learning · Computer Science 2026-02-11 Yifei Cheng , Xianglin Yang , Guoxia Wang , Chao Huang , Fei Ma , Dianhai Yu , Xiaochun Cao , Li Shen

Recent advancements in learning algorithms have demonstrated that the sharpness of the loss surface is an effective measure for improving the generalization gap. Building upon this concept, Sharpness-Aware Minimization (SAM) was proposed to…

Machine Learning · Computer Science 2024-06-21 Tanapat Ratchatorn , Masayuki Tanaka

Despite extensive studies, the underlying reason as to why overparameterized neural networks can generalize remains elusive. Existing theory shows that common stochastic optimizers prefer flatter minimizers of the training loss, and thus a…

Machine Learning · Computer Science 2023-07-25 Kaiyue Wen , Zhiyuan Li , Tengyu Ma

Sharpness-aware minimization (SAM) is to improve model generalization by searching for flat minima in the loss landscape. The SAM update consists of one step for computing the perturbation and the other for computing the update gradient.…

Machine Learning · Computer Science 2024-08-16 Xuehao Wang , Weisen Jiang , Shuai Fu , Yu Zhang

Data augmentation is one of the most effective techniques to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability in medical image analysis, it is frequently underutilized. This…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Adam Tupper , Christian Gagné

In this extended abstract, we will present and discuss opportunities and challenges brought about by a new deep learning method by AUC maximization (aka \underline{\bf D}eep \underline{\bf A}UC \underline{\bf M}aximization or {\bf DAM}) for…

Machine Learning · Computer Science 2021-11-05 Tianbao Yang

The mechanisms by which certain training interventions, such as increasing learning rates and applying batch normalization, improve the generalization of deep networks remains a mystery. Prior works have speculated that "flatter" solutions…

Machine Learning · Computer Science 2023-05-25 Simran Kaur , Jeremy Cohen , Zachary C. Lipton

How to train deep neural networks (DNNs) to generalize well is a central concern in deep learning, especially for severely overparameterized networks nowadays. In this paper, we propose an effective method to improve the model…

Machine Learning · Computer Science 2022-06-28 Yang Zhao , Hao Zhang , Xiuyuan Hu

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Model compression by way of parameter pruning, quantization, or distillation has recently gained popularity as an approach for reducing the computational requirements of modern deep neural network models for NLP. Inspired by prior works…

Computation and Language · Computer Science 2023-10-10 Clara Na , Sanket Vaibhav Mehta , Emma Strubell

We have witnessed remarkable progress in foundation models in vision tasks. Currently, several recent works have utilized the segmenting anything model (SAM) to boost the segmentation performance in medical images, where most of them focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Haoran Wang , Lian Huai , Wenbin Li , Lei Qi , Xingqun Jiang , Yinghuan Shi

Domain Generalization (DG) aims to reduce domain shifts between domains to achieve promising performance on the unseen target domain, which has been widely practiced in medical image segmentation. Single-source domain generalization (SDG)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Hanhui Wang , Huaize Ye , Yi Xia , Xueyan Zhang

The Segment Anything Model (SAM) exhibits impressive capabilities in zero-shot segmentation for natural images. Recently, SAM has gained a great deal of attention for its applications in medical image segmentation. However, to our best…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Pengfei Gu , Zihan Zhao , Hongxiao Wang , Yaopeng Peng , Yizhe Zhang , Nishchal Sapkota , Chaoli Wang , Danny Z. Chen

We develop regularization methods to find flat minima while training deep neural networks. These minima generalize better than sharp minima, yielding models outperforming baselines on real-world test data (which may be distributed…

Machine Learning · Computer Science 2025-07-04 Adam Sandler , Diego Klabjan , Yuan Luo

While the traditional formulation of machine learning tasks is in terms of performance on average, in practice we are often interested in how well a trained model performs on rare or difficult data points at test time. To achieve more…

Machine Learning · Computer Science 2025-12-29 Matthew J. Holland , Toma Hamada

Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Chang Qi , Junyang Chen , Guizhi Xu , Zhenghua Xu , Thomas Lukasiewicz , Yang Liu

We propose SAMed, a general solution for medical image segmentation. Different from the previous methods, SAMed is built upon the large-scale image segmentation model, Segment Anything Model (SAM), to explore the new research paradigm of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Kaidong Zhang , Dong Liu

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang