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Vision Transformers are at the heart of the current surge of interest in foundation models for histopathology. They process images by breaking them into smaller patches following a regular grid, regardless of their content. Yet, not all…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Clément Grisi , Geert Litjens , Jeroen van der Laak

Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

Computer vision is experiencing an AI renaissance, in which machine learning models are expediting important breakthroughs in academic research and commercial applications. Effectively training these models, however, is not trivial due in…

Machine Learning · Computer Science 2018-01-23 Jeff Kinnison , Nathaniel Kremer-Herman , Douglas Thain , Walter Scheirer

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Digital pathology offers a groundbreaking opportunity to transform clinical practice in histopathological image analysis, yet faces a significant hurdle: the substantial file sizes of pathological Whole Slide Images (WSI). While current…

Deep learning-based medical image-to-mesh reconstruction has rapidly evolved, enabling the transformation of medical imaging data into three-dimensional mesh models that are critical in computational medicine and in silico trials for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Fengming Lin , Arezoo Zakeri , Yidan Xue , Michael MacRaild , Haoran Dou , Zherui Zhou , Ziwei Zou , Ali Sarrami-Foroushani , Jinming Duan , Alejandro F. Frangi

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Foundation models have significantly advanced medical image analysis through the pre-train fine-tune paradigm. Among various fine-tuning algorithms, Parameter-Efficient Fine-Tuning (PEFT) is increasingly utilized for knowledge transfer…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Raman Dutt , Linus Ericsson , Pedro Sanchez , Sotirios A. Tsaftaris , Timothy Hospedales

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

Fine-tuning visual models has been widely shown promising performance on many downstream visual tasks. With the surprising development of pre-trained visual foundation models, visual tuning jumped out of the standard modus operandi that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Bruce X. B. Yu , Jianlong Chang , Haixin Wang , Lingbo Liu , Shijie Wang , Zhiyu Wang , Junfan Lin , Lingxi Xie , Haojie Li , Zhouchen Lin , Qi Tian , Chang Wen Chen

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Foundation models trained on large-scale pathology image corpora have demonstrated strong transfer capabilities across diverse histopathology tasks. Building on this progress, we introduce PLUTO-4, our next generation of pathology…

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Pre-trained vision models (PVMs) have demonstrated remarkable adaptability across a wide range of downstream vision tasks, showcasing exceptional performance. However, as these models scale to billions or even trillions of parameters,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Yi Xin , Jianjiang Yang , Siqi Luo , Yuntao Du , Qi Qin , Kangrui Cen , Yangfan He , Zhiwei Zhang , Bin Fu , Xiaokang Yang , Guangtao Zhai , Ming-Hsuan Yang , Xiaohong Liu

Accurate identification and localization of anatomical structures of varying size and appearance in laparoscopic imaging are necessary to leverage the potential of computer vision techniques for surgical decision support. Segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Fiona R. Kolbinger , Jiangpeng He , Jinge Ma , Fengqing Zhu

Medical image segmentation and video object segmentation are essential for diagnosing and analyzing diseases by identifying and measuring biological structures. Recent advances in natural domain have been driven by foundation models like…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Zhiling Yan , Weixiang Sun , Rong Zhou , Zhengqing Yuan , Kai Zhang , Yiwei Li , Tianming Liu , Quanzheng Li , Xiang Li , Lifang He , Lichao Sun

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He
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