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Knee osteoarthritis frequently exhibits discordance between structural damage observed in imaging and patient-reported symptoms such as pain. This mismatch complicates clinical interpretation and patient stratification and remains…

Machine Learning · Computer Science 2026-04-21 Pegah Ahadian , Mingrui Yang , Sixu Chen , Xiaojuan Li , Qiang Guan

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhisen Hu , Dominic Cullen , David S. Johnson , Aleksei Tiulpin , Timothy F. Cootes , Claudia Lindner

This paper introduces a new approach to automatically quantify the severity of knee OA using X-ray images. Automatically quantifying knee OA severity involves two steps: first, automatically localizing the knee joints; next, classifying the…

Computer Vision and Pattern Recognition · Computer Science 2017-03-30 Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O'Connor

Knee osteoarthritis (KOA) is a degenerative joint disease that can lead to chronic pain, reduced mobility, and long-term disability. Automated severity grading from knee radiographs can support early assessment, but current methods heavily…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Chandravardhan Singh Raghaw , Anushka Parwal , Shahid Shafi Dar , Prajakta Darade , Nagendra Kumar

The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…

Machine Learning · Computer Science 2025-05-30 Niamh Belton , Aonghus Lawlor , Kathleen M. Curran

Objective assessment of Magnetic Resonance Imaging (MRI) scans of osteoarthritis (OA) can address the limitation of the current OA assessment. Segmentation of bone, cartilage, and joint fluid is necessary for the OA objective assessment.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Jacob L. Jaremko , Janet L. Ronsky

This work proposes a novel end-to-end convolutional neural network (CNN) architecture to automatically quantify the severity of knee osteoarthritis (OA) using X-Ray images, which incorporates trainable attention modules acting as…

Image and Video Processing · Electrical Eng. & Systems 2019-08-26 Marc Górriz , Joseph Antony , Kevin McGuinness , Xavier Giró-i-Nieto , Noel E. O'Connor

Knee osteoarthritis (OA) is a major cause of disability worldwide and is still largely assessed using subjective radiographic grading, most commonly the Kellgren-Lawrence (KL) scale. Artificial intelligence (AI) and radiomics offer…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Abbas Alzubaidi , Ali Al-Bayaty

Knee Osteoarthritis (KOA) is the third most prevalent Musculoskeletal Disorder (MSD) after neck and back pain. To monitor such a severe MSD, a segmentation map of the femur, tibia and tibiofemoral cartilage is usually accessed using the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Akshay Daydar , Alik Pramanick , Arijit Sur , Subramani Kanagaraj

Osteoarthritis (OA) is the most prevalent chronic joint disease worldwide, where knee OA takes more than 80% of commonly affected joints. Knee OA is not a curable disease yet, and it affects large columns of patients, making it costly to…

Artificial Intelligence · Computer Science 2022-12-23 Soheyla Amirian , Husam Ghazaleh , Mehdi Assefi , Hilal Maradit Kremers , Hamid R. Arabnia , Johannes F. Plate , Ahmad P. Tafti

The severity of knee osteoarthritis is graded using the 5-point Kellgren-Lawrence (KL) scale where healthy knees are assigned grade 0, and the subsequent grades 1-4 represent increasing severity of the affliction. Although several methods…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Sudeep Kondal , Viraj Kulkarni , Ashrika Gaikwad , Amit Kharat , Aniruddha Pant

Conventional imaging diagnostics frequently encounter bottlenecks due to manual inspection, which can lead to delays and inconsistencies. Although deep learning offers a pathway to automation and enhanced accuracy, foundational models in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Aymen Sekhri , Marouane Tliba , Mohamed Amine Kerkouri , Yassine Nasser , Aladine Chetouani , Alessandro Bruno , Rachid Jennane

Osteoarthritis (OA) is one of the major health issues among the elderly population. MRI is the most popular technology to observe and evaluate the progress of OA course. However, the extreme labor cost of MRI analysis makes the process…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Boyu Zhang , Yingtao Zhang , H. D. Cheng , Min Xian , Shan Gai , Olivia Cheng , Kuan Huang

Objective: To assess the ability of imaging-based deep learning to predict radiographic patellofemoral osteoarthritis (PFOA) from knee lateral view radiographs. Design: Knee lateral view radiographs were extracted from The Multicenter…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Progression of hip osteoarthritis (hip OA) leads to pain and disability, likely leading to surgical treatment such as hip arthroplasty at the terminal stage. The severity of hip OA is often classified using the Crowe and Kellgren-Lawrence…

Disease-modifying management aims to prevent deterioration and progression of the disease, not just relieve symptoms. Unfortunately, the development of necessary therapies is often hampered by the failure to recognize the presymptomatic…

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Tian Lan , Lei Xu , Zimu Yuan , Shanggui Liu , Jiajun Liu , Jiaxin Liu , Weilai Xiang , Hongyu Yang , Dong Jiang , Jianxin Yin , Dingyu Wang

Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders and requires early-stage diagnosis. Nowadays, the deep convolutional neural networks have achieved greatly in the computer-aided diagnosis field. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Jiayu Huo , Liping Si , Xi Ouyang , Kai Xuan , Weiwu Yao , Zhong Xue , Qian Wang , Dinggang Shen , Lichi Zhang

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang