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Osteoarthritis (OA) is the most common musculoskeletal disease, with knee OA (KOA) being one of the leading causes of disability and a significant economic burden. Predicting KOA progression is crucial for improving patient outcomes,…

Machine Learning · Computer Science 2025-04-09 Khanh Nguyen , Huy Hoang Nguyen , Egor Panfilov , Aleksei Tiulpin

Radiographic grading of knee osteoarthritis (KOA) with the Kellgren-Lawrence (KL) system is limited by inter-reader variability and the opacity of current deep learning approaches, which predict KL grades directly from images without…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Azmul A. Irfan , Nur Ahmad Khatim , Alfan Alfian Irfan , Achmad Zaki , Erike A. Suwarsono , Mansur M. Arief

Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Petri Lehenkari , Simo Saarakkala

Knee-Joint Osteoarthritis (KOA) is a prevalent cause of global disability and is inherently complex to diagnose due to its subtle radiographic markers and individualized progression. One promising classification avenue involves applying…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang

This paper proposes a new approach to automatically quantify the severity of knee osteoarthritis (OA) from radiographs using deep convolutional neural networks (CNN). Clinically, knee OA severity is assessed using Kellgren \& Lawrence (KL)…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Joseph Antony , Kevin McGuinness , Noel E O Connor , Kieran Moran

This research paper explores the classification of knee osteoarthritis (OA) severity levels using advanced computer vision models and augmentation techniques. The study investigates the effectiveness of data preprocessing, including…

Knee osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Diagnosing OA severity typically requires expert assessment of X-ray images and is commonly based on the Kellgren-Lawrence grading system, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Nicharee Srikijkasemwat , Soumya Snigdha Kundu , Fuping Wu , Bartlomiej W. Papiez

Knee osteoarthritis (OA) is very common progressive and degenerative musculoskeletal disease worldwide creates a heavy burden on patients with reduced quality of life and also on society due to financial impact. Therefore, any attempt to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow…

Artificial Intelligence · Computer Science 2025-11-26 Weizhi Liu , Xi Chen , Zekun Jiang , Liang Zhao , Kunyuan Jiang , Ruisi Tang , Li Wang , Mingke You , Hanyu Zhou , Hongyu Chen , Qiankun Xiong , Yong Nie , Kang Li , Jian Li

Diagnosing knee osteoarthritis (OA) early is crucial for managing symptoms and preventing further joint damage, ultimately improving patient outcomes and quality of life. In this paper, a bioimpedance-based diagnostic tool that combines…

Signal Processing · Electrical Eng. & Systems 2025-05-06 Jamal Al-Nabulsi , Mohammad Al-Sayed Ahmad , Baraa Hasaneiah , Fayhaa AlZoubi

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

Medical Physics · Physics 2022-09-05 Anastasis Alexopoulos , Jukka Hirvasniemi , Nazli Tümer

Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due to limited diagnostic tools. This study presents an AI-powered system that analyzes knee…

Osteoarthritis (OA) is a common musculoskeletal condition typically diagnosed from radiographic assessment after clinical examination. However, a visual evaluation made by a practitioner suffers from subjectivity and is highly dependent on…

Computer Vision and Pattern Recognition · Computer Science 2017-04-07 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Simo Saarakkala

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Knee Osteoarthritis (KOA) is a common musculoskeletal condition that significantly affects mobility and quality of life, particularly in elderly populations. However, training deep learning models for early KOA classification is often…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Zhe Wang , Aladine Chetouani , Mohamed Jarraya , Yung Hsin Chen , Yuhua Ru , Fang Chen , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

We developed deep learning models for predicting Total Knee Replacement (TKR) need within various time horizons in knee osteoarthritis patients, with a novel capability: the models can perform TKR prediction using a single scan, and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Haresh Rengaraj Rajamohan , Richard Kijowski , Kyunghyun Cho , Cem M. Deniz

This chapter presents the investigations and the results of feature learning using convolutional neural networks to automatically assess knee osteoarthritis (OA) severity and the associated clinical and diagnostic features of knee OA from…

Computer Vision and Pattern Recognition · Computer Science 2019-08-26 Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O' Connor

Knee osteoarthritis (KOA) is a common joint disease that causes pain and mobility issues. While MRI-based deep learning models have demonstrated superior performance in predicting total knee replacement (TKR) and disease progression, their…

Image and Video Processing · Electrical Eng. & Systems 2026-05-27 Ehsan Karami , Hamid Soltanian-Zadeh