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Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…

Quantitative Methods · Quantitative Biology 2017-03-28 Harikrishnan Jayamohan , Valentin Romanov , Huizhong Li , Jiyoung Son , Raheel Samuel , John Nelson , Bruce Gale

Microfluidic systems are now being designed with precision to execute increasingly complex tasks. However, their operation often requires numerous external control devices due to the typically linear nature of microscale flows, which has…

Fluid Dynamics · Physics 2020-05-29 Daniel J. Case , Yifan Liu , Istvan Z. Kiss , Jean-Regis Angilella , Adilson E. Motter

Blood clotting involves the coupled processes of platelet aggregation and coagulation. Simulating clotting under flow in complex geometries is challenging due to multiple temporal and spatial scales and high computational cost. clotFoam is…

Fluid Dynamics · Physics 2023-08-07 David Montgomery , Federico Municchi , Karin Leiderman

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

Soft colloids are increasingly used as model systems to address fundamental issues such as crystallisation and the glass and jamming transitions. Among the available classes of soft colloids, microgels are emerging as the gold standard.…

Controlling the shape and position of moving and pinned droplets on a solid surface is an important feature often found in microfluidic applications. However, automating them, e.g., for high-throughput applications, does rarely involve…

Fluid Dynamics · Physics 2020-07-09 Henning Bonart , Christian Kahle , Jens-Uwe Repke

Internal recirculation in a moving droplet plays an important role in several droplet-based microfluidic devices as it enhances mixing, chemical reaction and heat transfer. The occurrence of fluid slip at the wall, which becomes prominent…

Fluid Dynamics · Physics 2013-11-26 Joseph J Thalakkottor , Kamran Mohseni

Dripping, jetting and tip streaming have been studied up to a certain point separately by both fluid mechanics and microfluidics communities, the former focusing on fundamental aspects while the latter on applications. Here, we intend to…

Fluid Dynamics · Physics 2020-06-22 Jose M. Montanero , Alfonso M. Ganan-Calvo

This chapter presents an overview of microfluidic devices reported in the literature, used to develop methodologies for nucleation of biomolecules, with crystal size control, and for collecting thermodynamic and kinetic data. Part I is…

Soft Condensed Matter · Physics 2025-12-16 Nadine Candoni , Romain Grossier , Stéphane Veesler

Microfluidic devices offer unique opportunities to directly observe multiphase flow in porous media. However, as a direct representation of flow in geological pore networks, conventional microfluidics face several challenges. One is that…

Fluid Dynamics · Physics 2026-03-11 S. J. Cox , A. Davarpanah , W. R. Rossen

An active area of research interest is the inference of ecological models of complex microbial communities. Inferring such ecological models entails understanding the interactions between microbes and how they affect each other's growth.…

Applications · Statistics 2022-10-19 William Krinsman

Primary hemostasis is initiated by platelet adhesion and aggregation at a site of vascular injury and is strongly regulated by local hydrodynamic conditions. At elevated shear rates, platelet capture is mediated by von Willebrand factor…

Biological Physics · Physics 2026-05-28 Alper Topuz , Gerhard Gompper , Dmitry A. Fedosov

The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis. This system integrates a 3D-printed microfluidic chip with image…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Yuanyuan Wei , Meiai Lin , Shanhang Luo , Syed Muhammad Tariq Abbasi , Liwei Tan , Guangyao Cheng , Bijie Bai , Yi-Ping Ho , Scott Wu Yuan , Ho-Pui Ho

We present experimental evidence of multiple blood flow configurations in a relatively simple microfluidic network under constant inlet conditions. We provide evidence of multistability and unsteady dynamics and find good agreement with a…

Owing to its conceptual simplicity and computational efficiency, the pseudopotential multiphase lattice Boltzmann (LB) model has attracted significant attention since its emergence. In this work, we aim to extend the pseudopotential LB…

Computational Physics · Physics 2013-05-07 Q. Li , K. H. Luo , X. J. Li

Dried blood spot (DBS) has risen in popularity due to the ease of sampling, storing, shipping and more. Despite those advantages, recovery of the dried blood in solution for analysis is still a bottleneck as it is manual, time-consuming and…

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

Instrumentation and Detectors · Physics 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

Soft Condensed Matter · Physics 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux

Inertial fluid flow deformation around pillars in a microchannel is a new method for controlling fluid flow. Sequences of pillars have been shown to produce a rich phase space with a wide variety of flow transformations. Previous work has…

The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…

Numerical Analysis · Mathematics 2021-10-15 Ting Wu , Keqin Liu , Emily Fainman , Ying Wang