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Accurate prediction and optimization of protein-protein binding affinity is crucial for therapeutic antibody development. Although machine learning-based prediction methods $\Delta\Delta G$ are suitable for large-scale mutant screening,…

Biomolecules · Quantitative Biology 2024-09-19 Kairi Furui , Masahito Ohue

Time series forecasting requires capturing patterns across multiple temporal scales while maintaining computational efficiency. This paper introduces AWGformer, a novel architecture that integrates adaptive wavelet decomposition with…

Machine Learning · Computer Science 2026-01-29 Wei Li

Less than 1% of protein sequences are structurally and functionally annotated. Natural Language Processing (NLP) community has recently embraced self-supervised learning as a powerful approach to learn representations from unlabeled text,…

Biomolecules · Quantitative Biology 2020-12-08 Modestas Filipavicius , Matteo Manica , Joris Cadow , Maria Rodriguez Martinez

With the scale of vision Transformer-based models continuing to grow, finetuning these large-scale pretrained models for new tasks has become increasingly parameter-intensive. Visual prompt tuning is introduced as a parameter-efficient…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Runjia Zeng , Cheng Han , Qifan Wang , Chunshu Wu , Tong Geng , Lifu Huang , Ying Nian Wu , Dongfang Liu

After AlphaFold won the Nobel Prize, protein prediction with deep learning once again became a hot topic. We comprehensively explore advanced deep learning methods applied to protein structure prediction and design. It begins by examining…

Large language models (LLMs) and multimodal models have become powerful general-purpose reasoning systems. However, radio-frequency (RF) signals, which underpin wireless systems, are still not natively supported by these models. Existing…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Hang Zou , Yu Tian , Bohao Wang , Lina Bariah , Samson Lasaulce , Chongwen Huang , Mérouane Debbah

Previous work on home router security has shown that using system calls to train a transformer-based language model built on a BERT-style encoder using contrastive learning is effective in detecting several types of malware, but the…

Cryptography and Security · Computer Science 2026-01-05 John Carter , Spiros Mancoridis , Pavlos Protopapas , Brian Mitchell , Benji Lilley

Current visual grounding models are either based on a Multimodal Large Language Model (MLLM) that performs auto-regressive decoding, which is slow and risks hallucinations, or on re-aligning an LLM with vision features to learn new special…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Weitai Kang , Jason Kuen , Mengwei Ren , Zijun Wei , Yan Yan , Kangning Liu

Attention based language models have become a critical component in state-of-the-art natural language processing systems. However, these models have significant computational requirements, due to long training times, dense operations and…

Computation and Language · Computer Science 2021-06-11 Ivan Chelombiev , Daniel Justus , Douglas Orr , Anastasia Dietrich , Frithjof Gressmann , Alexandros Koliousis , Carlo Luschi

The classification of exoplanets has been a longstanding challenge in astronomy, requiring significant computational and observational resources. Traditional methods demand substantial effort, time, and cost, highlighting the need for…

Earth and Planetary Astrophysics · Physics 2025-06-23 Anupma Choudhary , Sohith Bandari , B. S. Kushvah , C. Swastik

Pre-trained vision-language models (VLMs) exhibit strong zero-shot generalization but remain vulnerable to adversarial perturbations. Existing classification-guided adversarial fine-tuning methods often disrupt pre-trained cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Yubo Cui , Xianchao Guan , Zijun Xiong , Zheng Zhang

Our work tackles the computational challenges of contrastive learning methods, particularly for the pretraining of Vision Transformers (ViTs). Despite the effectiveness of contrastive learning, the substantial computational resources…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinhong Lin , Cheng-En Wu , Yibing Wei , Pedro Morgado

Synthesizing medical images, such as PET, is a challenging task due to the fact that the intensity range is much wider and denser than those in photographs and digital renderings and are often heavily biased toward zero. Above all,…

With the emergence of Transformer architectures and their powerful understanding of textual data, a new horizon has opened up to predict the molecular properties based on text description. While SMILES are the most common form of…

Chemical Physics · Physics 2023-10-11 Suryanarayanan Balaji , Rishikesh Magar , Yayati Jadhav , Amir Barati Farimani

This paper describes a system submitted by team BigGreen to LCP 2021 for predicting the lexical complexity of English words in a given context. We assemble a feature engineering-based model with a deep neural network model founded on BERT.…

Computation and Language · Computer Science 2021-07-29 Aadil Islam , Weicheng Ma , Soroush Vosoughi

Transformer-based pretrained large language models (PLM) such as BERT and GPT have achieved remarkable success in NLP tasks. However, PLMs are prone to encoding stereotypical biases. Although a burgeoning literature has emerged on…

Computation and Language · Computer Science 2024-06-18 Yi Yang , Hanyu Duan , Ahmed Abbasi , John P. Lalor , Kar Yan Tam

Machine based text comprehension has always been a significant research field in natural language processing. Once a full understanding of the text context and semantics is achieved, a deep learning model can be trained to solve a large…

Computation and Language · Computer Science 2020-09-03 Omar Mossad , Amgad Ahmed , Anandharaju Raju , Hari Karthikeyan , Zayed Ahmed

We propose a Vision-Language Transformer (VLT) framework for referring segmentation to facilitate deep interactions among multi-modal information and enhance the holistic understanding to vision-language features. There are different ways…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Henghui Ding , Chang Liu , Suchen Wang , Xudong Jiang

Recently, large multimodal models (LMMs) have achieved significant advancements. When dealing with high-resolution images, dominant LMMs typically divide them into multiple local images and a global image, leading to a large number of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Zhibin Lan , Liqiang Niu , Fandong Meng , Wenbo Li , Jie Zhou , Jinsong Su

The global demand for radiologists is increasing rapidly due to a growing reliance on medical imaging services, while the supply of radiologists is not keeping pace. Advances in computer vision and image processing technologies present…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Shehroz S. Khan , Petar Przulj , Ahmed Ashraf , Ali Abedi