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Graph Neural Networks (GNNs) have achieved significant success across various applications. However, their complex structures and inner workings can be challenging for non-AI experts to understand. To address this issue, this study presents…

Human-Computer Interaction · Computer Science 2025-12-18 Yilin Lu , Chongwei Chen , Yuxin Chen , Kexin Huang , Marinka Zitnik , Qianwen Wang

The recent rise of cryo-EM and X-ray high-throughput techniques is providing a wealth of new structures trapped in different conformations. Understanding how proteins transition between different conformers, and how they relate to each…

Biomolecules · Quantitative Biology 2018-03-20 Laura Orellana , Johan Gustavsson , Cathrine Bergh , Ozge Yoluk , Erik Lindahl

3D modeling is becoming a well-developed field of medicine, but its applicability can be limited due to the lack of software allowing for easy utilizations of generated 3D visualizations. By leveraging recent advances in virtual reality, we…

Human-Computer Interaction · Computer Science 2020-12-07 Alex J. Deakyne , Erik N. Gaasedelen , Tinen L. Iles , Paul A. Iaizzo

Determining the interaction strength between proteins and small molecules is key to analyzing their biological function. Quantum-mechanical calculations such as \emph{Density Functional Theory} (DFT) give accurate and theoretically…

Data Structures and Algorithms · Computer Science 2016-06-13 Moritz von Looz , Mario Wolter , Christoph R. Jacob , Henning Meyerhenke

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

Quantitative Methods · Quantitative Biology 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Developing an algorithm for a visualization prototype often involves the direct comparison of different development stages and design decisions, and even minor modifications may dramatically affect the results. While existing development…

Software Engineering · Computer Science 2020-01-08 Fabian Bolte , Stefan Bruckner

Background: Coronary artery bypass grafting (CABG) planning requires advanced spatial visualization and consideration of coronary artery depth, calcification, and pericardial adhesions. Objective: To develop and evaluate a dynamic…

Medical Physics · Physics 2025-10-02 Shuo Wang , Tong Ren , Nan Cheng , Li Zhang , Rong Wang

Protein structure prediction is pivotal for understanding the structure-function relationship of proteins, advancing biological research, and facilitating pharmaceutical development and experimental design. While deep learning methods and…

Machine Learning · Computer Science 2024-12-30 Kaihui Cheng , Ce Liu , Qingkun Su , Jun Wang , Liwei Zhang , Yining Tang , Yao Yao , Siyu Zhu , Yuan Qi

We present a data-driven framework to automate the vectorization and machine interpretation of 2D engineering part drawings. In industrial settings, most manufacturing engineers still rely on manual reads to identify the topological and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Wentai Zhang , Joe Joseph , Yue Yin , Liuyue Xie , Tomotake Furuhata , Soji Yamakawa , Kenji Shimada , Levent Burak Kara

We introduce ProteinWorkshop, a comprehensive benchmark suite for representation learning on protein structures with Geometric Graph Neural Networks. We consider large-scale pre-training and downstream tasks on both experimental and…

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Biomolecules · Quantitative Biology 2015-04-15 Adam J. M. Wollman , Helen Miller , Zhaokun Zhou , Mark C. Leake

Graph theory and graph mining constitute rich fields of computational techniques to study the structures, topologies and properties of graphs. These techniques constitute a good asset in bioinformatics if there exist efficient methods for…

Biomolecules · Quantitative Biology 2016-04-04 Wajdi Dhifli , Abdoulaye Baniré Diallo

Online user studies of visualizations, visual encodings, and interaction techniques are ubiquitous in visualization research. Yet, designing, conducting, and analyzing studies effectively is still a major burden. Although various packages…

Modeling and simulating the protein folding process overall remains a grand challenge in computational biology. We systematically investigate end-to-end quantum algorithms for simulating various protein dynamics with effects, such as…

Quantum Physics · Physics 2025-04-17 Zhenning Liu , Xiantao Li , Chunhao Wang , Jin-Peng Liu

Background. Within the software industry, it is commonly estimated that software professionals invest a substantial portion of their work hours in the process of understanding existing systems. In this context, an ineffective technical…

Software Engineering · Computer Science 2024-01-19 Fernando Padoan , Ronnie de Souza Santos , Rodrigo Pessoa Medeiros

Purpose: Development of a novel interactive visualization approach for the exploration of radiotherapy treatment plans with a focus on overlap volumes with the aim of healthy tissue sparing. Methods: We propose a visualization approach to…

Human-Computer Interaction · Computer Science 2023-10-03 Matthias Schlachter , Samuel Peters , Daniel Camenisch , Paul Martin Putora , Katja Bühler

We provide a visualization model that targets the visualization of Protein-Protein Interactions(PPI) and combines it with a super view based on publications and methods to extract interactions. Although there are several existing tools, our…

Information Retrieval · Computer Science 2021-11-29 Melih Sozdinler

Recently, biclustering is one of the hot topics in bioinformatics and takes the attention of authors from several different disciplines. Hence, many different methodologies from a variety of disciplines are proposed as a solution to the…

Human-Computer Interaction · Computer Science 2021-11-26 Melih Sozdinler

Cloth folding is a widespread domestic task that is seemingly performed by humans but which is highly challenging for autonomous robots to execute due to the highly deformable nature of textiles; It is hard to engineer and learn…

Robotics · Computer Science 2021-10-19 Peng Zhou , Omar Zahra , Anqing Duan , Shengzeng Huo , Zeyu Wu , David Navarro-Alarcon

Recent advances in vision-language models (VLMs) have achieved impressive results on standard image-text tasks, yet their potential for visual procedure question answering (VP-QA) remains largely unexplored. VP-QA presents unique challenges…

Computation and Language · Computer Science 2026-05-15 Guanhua Chen , Yutong Yao , Shenghe Sun , Ci-Jun Gao , Shudong Liu , Lidia S. Chao , Feng Wan , Derek F. Wong