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Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

Finding the minimum distance of linear codes is an NP-hard problem. Traditionally, this computation has been addressed by means of the design of algorithms that find, by a clever exhaustive search, a linear combination of some generating…

Information Theory · Computer Science 2020-11-02 M. P. Cuéllar , J. Gómez-Torrecillas , F. J. Lobillo , G. Navarro

Phylogenetic networks are used to represent the evolutionary history of species. They are versatile when compared to traditional phylogenetic trees, as they capture more complex evolutionary events such as hybridization and horizontal gene…

Combinatorics · Mathematics 2023-05-18 Shunsuke Maeda , Yusuke Kaneko , Hideaki Muramatsu , Yukihiro Murakami , Momoko Hayamizu

Selective inference is considered for testing trees and edges in phylogenetic tree selection from molecular sequences. This improves the previously proposed approximately unbiased test by adjusting the selection bias when testing many trees…

Applications · Statistics 2019-05-27 Hidetoshi Shimodaira , Yoshikazu Terada

Phylogenetic trees and networks are leaf-labelled graphs used to model evolution. Display graphs are created by identifying common leaf labels in two or more phylogenetic trees or networks. The treewidth of such graphs is bounded as a…

Data Structures and Algorithms · Computer Science 2018-09-05 Remie Janssen , Mark Jones , Steven Kelk , Georgios Stamoulis , Taoyang Wu

We present the first sub-quadratic time algorithm that with high probability correctly reconstructs phylogenetic trees for short sequences generated by a Markov model of evolution. Due to rapid expansion in sequence databases, such very…

Populations and Evolution · Quantitative Biology 2012-06-01 Daniel G. Brown , Jakub Truszkowski

Classification of gene trees is an important task both in the analysis of multi-locus phylogenetic data, and assessment of the convergence of Markov Chain Monte Carlo (MCMC) analyses used in Bayesian phylogenetic tree reconstruction. The…

Combinatorics · Mathematics 2024-06-10 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

Phylogenetic networks are used to represent evolutionary scenarios in biology and linguistics. To find the most probable scenario, it may be necessary to compare candidate networks, to distinguish different networks, and to see when one…

Combinatorics · Mathematics 2020-04-10 Remie Janssen , Yukihiro Murakami

The log-det distance between two aligned DNA sequences was introduced as a tool for statistically consistent inference of a gene tree under simple non-mixture models of sequence evolution. Here we prove that the log-det distance, coupled…

Populations and Evolution · Quantitative Biology 2018-06-14 Elizabeth S. Allman , Colby Long , John A. Rhodes

Ranked tree-child networks are a recently introduced class of rooted phylogenetic networks in which the evolutionary events represented by the network are ordered so as to respect the flow of time. This class includes the well-studied…

Populations and Evolution · Quantitative Biology 2024-10-15 Vincent Moulton , Andreas Spillner

For a given set $\mathcal{L}$ of species and a set $\mathcal{T}$ of triplets on $\mathcal{L}$, one wants to construct a phylogenetic network which is consistent with $\mathcal{T}$, i.e which represents all triplets of $\mathcal{T}$. The…

Populations and Evolution · Quantitative Biology 2015-03-19 Michel Habib , Thu-Hien To

In this work, we answer an open problem in the study of phylogenetic networks. Phylogenetic trees are rooted binary trees in which all edges are directed away from the root, whereas phylogenetic networks are rooted acyclic digraphs. For the…

Populations and Evolution · Quantitative Biology 2015-11-12 Andreas D. M. Gunawan , Bhaskar DasGupta , Louxin Zhang

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

Combinatorics · Mathematics 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

Spatial networks are networks where nodes are located in a space equipped with a metric. Typically, the space is two-dimensional and until recently and traditionally, the metric that was usually considered was the Euclidean distance. In…

Combinatorics · Mathematics 2022-11-29 Ramon Ferrer-i-Cancho

Phylogenetic networks are directed acyclic graphs that depict the genomic evolution of related taxa. Reticulation nodes in such networks (nodes with more than one parent) represent reticulate evolutionary events, such as recombination,…

Populations and Evolution · Quantitative Biology 2024-11-21 Alexey Markin , Sriram Vijendran , Oliver Eulenstein

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

Large tree structures are ubiquitous and real-world relational datasets often have information associated with nodes (e.g., labels or other attributes) and edges (e.g., weights or distances) that need to be communicated to the viewers. Yet,…

Computational Geometry · Computer Science 2023-05-18 Kathryn Gray , Mingwei Li , Reyan Ahmed , Md. Khaledur Rahman , Ariful Azad , Stephen Kobourov , Katy Börner

In evolutionary biology, genetic sequences carry with them a trace of the underlying tree that describes their evolution from a common ancestral sequence. The question of how many sequence sites are required to recover this evolutionary…

Populations and Evolution · Quantitative Biology 2008-06-17 Mareike Fischer , Mike Steel

Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.…

Populations and Evolution · Quantitative Biology 2011-01-11 Roland F. Schwarz , William Fletcher , Frank Förster , Benjamin Merget , Matthias Wolf , Jörg Schultz , Florian Markowetz

Network alignment aims to find regions of topological or functional similarities between networks. In computational biology, it can be used to transfer biological knowledge from a well-studied species to a poorly-studied species between…

Molecular Networks · Quantitative Biology 2014-10-21 Joseph Crawford , Tijana Milenković
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