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The path-difference metric is one of the oldest distances for the comparison of fully resolved phylogenetic trees, but its statistical properties are still quite unknown. In this paper we compute the mean value of the square of the…

Populations and Evolution · Quantitative Biology 2009-06-16 Arnau Mir , Francesc Rossello

A phylogenetic network is a directed acyclic graph that visualises an evolutionary history containing so-called reticulations such as recombinations, hybridisations or lateral gene transfers. Here we consider the construction of a simplest…

Populations and Evolution · Quantitative Biology 2008-05-16 Leo van Iersel , Steven Kelk

Rooted phylogenetic networks provide an explicit representation of the evolutionary history of a set $X$ of sampled species. In contrast to phylogenetic trees which show only speciation events, networks can also accommodate reticulate…

Combinatorics · Mathematics 2021-01-01 Peter L. Erdos , Charles Semple , Mike Steel

The Discrepancy of a hypergraph is the minimum attainable value, over two-colorings of its vertices, of the maximum absolute imbalance of any hyperedge. The Hereditary Discrepancy of a hypergraph, defined as the maximum discrepancy of a…

Data Structures and Algorithms · Computer Science 2014-07-24 Aleksandar Nikolov , Kunal Talwar

Distance based algorithms are a common technique in the construction of phylogenetic trees from taxonomic sequence data. The first step in the implementation of these algorithms is the calculation of a pairwise distance matrix to give a…

Populations and Evolution · Quantitative Biology 2007-05-23 J G Sumner , P D Jarvis

Phylogenetic trees are leaf-labelled trees used to model the evolution of species. In practice it is not uncommon to obtain two topologically distinct trees for the same set of species, and this motivates the use of distance measures to…

Data Structures and Algorithms · Computer Science 2026-03-24 David Mestel , Steven Chaplick , Steven Kelk , Ruben Meuwese

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In a recent series of papers devoted to the…

Populations and Evolution · Quantitative Biology 2007-07-17 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Phylogenetic trees represent certain species and their likely ancestors. In such a tree, present-day species are leaves and an edge from u to v indicates that u is an ancestor of v. Weights on these edges indicate the phylogenetic distance.…

Populations and Evolution · Quantitative Biology 2025-10-08 Jannik Schestag

Cycles are ubiquitous in various networks such as social, biological, and technological systems, where they play a significant functional and dynamical role. This paper proposes a node similarity measure based on minimal simple cycles,…

Physics and Society · Physics 2026-01-30 Bo Yang

We study augmenting a plane Euclidean network with a segment, called a shortcut, to minimize the largest distance between any two points along the edges of the resulting network. Problems of this type have received considerable attention…

Computational Geometry · Computer Science 2018-07-27 Delia Garijo , Alberto Márquez , Natalia Rodríguez , Rodrigo I. Silveira

In molecular systematics, evolutionary trees are reconstructed from sequences at the tips under simple models of site substitution. A central question is how much sequence data is required to reconstruct a tree accurately? The answer…

Quantitative Methods · Quantitative Biology 2012-07-18 Iain Martyn , Mike Steel

Phylogenetic networks are a generalization of evolutionary trees that are used by biologists to represent the evolution of organisms which have undergone reticulate evolution. Essentially, a phylogenetic network is a directed acyclic graph…

Populations and Evolution · Quantitative Biology 2017-02-01 Leo van Iersel , Vincent Moulton , Eveline de Swart , Taoyang Wu

Let $G$ be an undirected graph. We say that $G$ contains a ladder of length $k$ if the $2 \times (k+1)$ grid graph is an induced subgraph of $G$ that is only connected to the rest of $G$ via its four cornerpoints. We prove that if all the…

Combinatorics · Mathematics 2024-01-31 Steven Chaplick , Steven Kelk , Ruben Meuwese , Matus Mihalak , Georgios Stamoulis

One strategy for reconstruction of phylogenetic networks is to solve the phylogenetic network problem, which involves inferring phylogenetic trees first and subsequently computing the smallest phylogenetic network that displays all the…

Combinatorics · Mathematics 2023-09-26 Laurent Bulteau , Louxin Zhang

A communication network can be modeled as a directed connected graph with edge weights that characterize performance metrics such as loss and delay. Network tomography aims to infer these edge weights from their pathwise versions measured…

Optimization and Control · Mathematics 2019-08-12 Mahmood Ettehad , Nick Duffield , Gregory Berkolaiko

The mutational heterogeneity of tumours can be described with a tree representing the evolutionary history of the tumour. With noisy sequencing data there may be uncertainty in the inferred tree structure, while we may also wish to study…

Computational Complexity · Computer Science 2025-01-14 Luís Cunha , Jack Kuipers , Thiago Lopes

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

Applications · Statistics 2021-11-29 Ali Amiryousefi

Phylogenetic inference can potentially result in a more accurate tree using data from multiple loci. However, if the loci are incongruent--due to events such as incomplete lineage sorting or horizontal gene transfer--it can be misleading to…

Populations and Evolution · Quantitative Biology 2016-03-10 Kevin Gori , Tomasz Suchan , Nadir Alvarez , Nick Goldman , Christophe Dessimoz

In several important routing contexts it is required to identify a set of routes, each of which optimizes a different criterion. For instance, in the context of vehicle routing, one route would minimize the total distance traveled, while…

Networking and Internet Architecture · Computer Science 2020-08-25 Ido Zoref , Ariel Orda

Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we…

Data Structures and Algorithms · Computer Science 2020-04-07 Mark Jones , Steven Kelk , Leen Stougie