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Large Multimodal Models (LMMs) achieve state-of-the-art performance in high-stakes domains like healthcare, yet their reasoning remains opaque. Current interpretability methods, such as attention mechanisms or post-hoc saliency, often fail…

Machine Learning · Computer Science 2026-04-30 Micky C. Nnamdi , Benoit L. Marteau , Yishan Zhong , J. Ben Tamo , May D. Wang

Research must be reproducible in order to make an impact on science and to contribute to the body of knowledge in our field. Yet studies have shown that 70% of research from academic labs cannot be reproduced. In software engineering, and…

Software Engineering · Computer Science 2018-04-10 Clinton Woodson , Jane Huffman Hayes , Sarah Griffioen

The exponential growth of scientific publications in recent years has posed a significant challenge in effective and efficient categorization. This paper introduces a novel approach that combines instance-based learning and ensemble…

Digital Libraries · Computer Science 2024-09-24 Fang Zhang , Shengli Wu

Retrieval-augmented generation (RAG) based large language models (LLMs) are widely used in finance for their excellent performance on knowledge-intensive tasks. However, standardized documents (e.g., SEC filing) share similar formats such…

Information Retrieval · Computer Science 2025-11-07 Jaeyoung Choe , Jihoon Kim , Woohwan Jung

Evaluating Information Retrieval (IR) systems relies on high-quality manual relevance judgments (qrels), which are costly and time-consuming to obtain. While pooling reduces the annotation effort, it results in only partially labeled…

Information Retrieval · Computer Science 2025-06-24 Catarina Pires , Sérgio Nunes , Luís Filipe Teixeira

Effective biomedical literature retrieval (BLR) plays a central role in precision medicine informatics. In this paper, we propose GRAPHENE, which is a deep learning based framework for precise BLR. GRAPHENE consists of three main different…

Information Retrieval · Computer Science 2019-11-22 Sendong Zhao , Chang Su , Andrea Sboner , Fei Wang

Although large language models (LLMs) demonstrate expert-level medical knowledge, aligning their open-ended outputs with fine-grained clinician preferences remains challenging. Existing methods often rely on coarse objectives or unreliable…

Artificial Intelligence · Computer Science 2026-02-12 Shiwei Lyu , Xidong Wang , Lei Liu , Hao Zhu , Chaohe Zhang , Jian Wang , Jinjie Gu , Benyou Wang , Yue Shen

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Algorithmic classifications of research publications can be used to study many different aspects of the science system, such as the organization of science into fields, the growth of fields, interdisciplinarity, and emerging topics. How to…

Digital Libraries · Computer Science 2021-01-01 Peter Sjögårde , Per Ahlgren , Ludo Waltman

Language models hold incredible promise for enabling scientific discovery by synthesizing massive research corpora. Many complex scientific research questions have multiple plausible answers, each supported by evidence of varying strength.…

Machine Learning · Computer Science 2025-05-28 Ravi Patel , Angus Brayne , Rogier Hintzen , Daniel Jaroslawicz , Georgiana Neculae , Dane Corneil

Large language models (LLMs) show promise in automating clinical diagnosis, yet their non-transparent decision-making and limited alignment with diagnostic standards hinder trust and clinical adoption. We address this challenge by proposing…

Artificial Intelligence · Computer Science 2025-11-25 Yining Yuan , J. Ben Tamo , Micky C. Nnamdi , Yifei Wang , May D. Wang

Iterative Retrieval-Augmented Generation (iRAG) has emerged as a powerful paradigm for answering complex multi-hop questions by progressively retrieving and reasoning over external documents. However, current systems predominantly operate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Peiyang Liu , Ziqiang Cui , Xi Wang , Di Liang , Wei Ye

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their…

Information Retrieval · Computer Science 2025-04-23 Mohit Gupta , Akiko Aizawa , Rajiv Ratn Shah

We present a scalable, AI-powered system that identifies and extracts evidence-based behavioral nudges from unstructured biomedical literature. Nudges are subtle, non-coercive interventions that influence behavior without limiting choice,…

Recent advancements in Large Language Models (LLMs) have marked significant progress in understanding and responding to medical inquiries. However, their performance still falls short of the standards set by professional consultations. This…

Computation and Language · Computer Science 2025-03-25 Kaiwen Zuo , Jing Tang , Hanbing Qin , Binli Luo , Ligang He , Shiyan Tang

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

We introduce the SEER (Span-based Emotion Evidence Retrieval) Benchmark to test Large Language Models' (LLMs) ability to identify the specific spans of text that express emotion. Unlike traditional emotion recognition tasks that assign a…

Computation and Language · Computer Science 2025-10-29 Aneesha Sampath , Oya Aran , Emily Mower Provost

Accuracy-based evaluation of Large Language Models (LLMs) measures benchmark-specific performance rather than underlying medical competency: it treats all questions as equally informative, conflates model ability with item characteristics,…

Computation and Language · Computer Science 2026-04-07 Zhimeng Luo , Lixin Wu , Adam Frisch , Daqing He

Classification is a core NLP task architecture with many potential applications. While large language models (LLMs) have brought substantial advancements in text generation, their potential for enhancing classification tasks remains…

Computation and Language · Computer Science 2026-01-30 Qian Ruan , Ilia Kuznetsov , Iryna Gurevych