English
Related papers

Related papers: Supporting Evidence-Based Medicine by Finding Both…

200 papers

Evidence-based medicine is the practice of making medical decisions that adhere to the latest, and best known evidence at that time. Currently, the best evidence is often found in the form of documents, such as randomized control trials,…

Computation and Language · Computer Science 2024-05-21 Anthony Hughes , Xingyi Song

Scientific reasoning requires not only long-chain reasoning processes, but also knowledge of domain-specific terminologies and adaptation to updated findings. To deal with these challenges for scientific reasoning, we introduce RAISE, a…

Computation and Language · Computer Science 2026-03-20 Minhae Oh , Jeonghye Kim , Nakyung Lee , Donggeon Seo , Taeuk Kim , Jungwoo Lee

Using Large Language Models (LLMs) for relevance assessments offers promising opportunities to improve Information Retrieval (IR), Natural Language Processing (NLP), and related fields. Indeed, LLMs hold the promise of allowing IR…

The growing use of large language models (LLMs) for biomedical question answering raises concerns about the accuracy and evidentiary support of their responses. To address this, we present Answered with Evidence, a framework for evaluating…

Machine Learning · Computer Science 2025-07-08 Julian D Baldwin , Christina Dinh , Arjun Mukerji , Neil Sanghavi , Saurabh Gombar

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

Learning efficient representations for concepts has been proven to be an important basis for many applications such as machine translation or document classification. Proper representations of medical concepts such as diagnosis, medication,…

Machine Learning · Computer Science 2016-02-18 Edward Choi , Mohammad Taha Bahadori , Elizabeth Searles , Catherine Coffey , Jimeng Sun

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

Large Language Models (LLMs) have been used as relevance assessors for Information Retrieval (IR) evaluation collection creation due to reduced cost and increased scalability as compared to human assessors. While previous research has…

Information Retrieval · Computer Science 2026-01-06 Samaneh Mohtadi , Gianluca Demartini

Manual relevance judgements in Information Retrieval are costly and require expertise, driving interest in using Large Language Models (LLMs) for automatic assessment. While LLMs have shown promise in general web search scenarios, their…

Information Retrieval · Computer Science 2025-04-18 Ratan J. Sebastian , Anett Hoppe

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

Asynchronous patient-clinician messaging via EHR portals is a growing source of clinician workload, prompting interest in large language models (LLMs) to assist with draft responses. However, LLM outputs may contain clinical inaccuracies,…

Computation and Language · Computer Science 2025-09-29 Wenyuan Chen , Fateme Nateghi Haredasht , Kameron C. Black , Francois Grolleau , Emily Alsentzer , Jonathan H. Chen , Stephen P. Ma

The fundamental process of evidence extraction and synthesis in evidence-based medicine involves extracting PICO (Population, Intervention, Comparison, and Outcome) elements from biomedical literature. However, Outcomes, being the most…

Computation and Language · Computer Science 2025-06-09 Yiliang Zhou , Abigail M. Newbury , Gongbo Zhang , Betina Ross Idnay , Hao Liu , Chunhua Weng , Yifan Peng

Metadata extraction is essential for cataloging and preserving datasets, enabling effective research discovery and reproducibility, especially given the current exponential growth in scientific research. While Masader (Alyafeai et al.,2021)…

Computation and Language · Computer Science 2025-09-19 Zaid Alyafeai , Maged S. Al-Shaibani , Bernard Ghanem

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by…

The automation of scientific research through large language models (LLMs) presents significant opportunities but faces critical challenges in knowledge synthesis and quality assurance. We introduce Feedback-Refined Agent Methodology…

Computation and Language · Computer Science 2025-11-18 Chengzhang Yu , Yiming Zhang , Zhixin Liu , Zenghui Ding , Yining Sun , Zhanpeng Jin

This paper reports the use of a document distance-based approach to automatically expand the number of available relevance judgements when these are limited and reduced to only positive judgements. This may happen, for example, when the…

Information Retrieval · Computer Science 2015-01-27 Diego Mollá , Iman Amini , David Martinez

Identification of appropriate supporting evidence is critical to the success of scientific fact checking. However, existing approaches rely on off-the-shelf Information Retrieval algorithms that rank documents based on relevance rather than…

Information Retrieval · Computer Science 2025-08-18 Xingyu Deng , Xi Wang , Mark Stevenson

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

Users increasingly expect modern search systems to offer a unified interface that seamlessly retrieves information from diverse data sources and formats. However, current information retrieval (IR) evaluation benchmarks have not kept pace…

Information Retrieval · Computer Science 2026-05-13 Mehmet Deniz Türkmen , Suchana Datta , Dwaipayan Roy , Daniel Hienert , Philipp Mayr , Derek Greene