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Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…
Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…
Melanoma is a life-threatening form of skin cancer when left undiagnosed at the early stages. Although there are more cases of non-melanoma cancer than melanoma cancer, melanoma cancer is more deadly. Early detection of melanoma is crucial…
Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…
Breast cancer is one of the common cancers that endanger the health of women globally. Accurate target lesion segmentation is essential for early clinical intervention and postoperative follow-up. Recently, many convolutional neural…
Convolutional Neural Networks (CNNs) have shown remarkable progress in medical image segmentation. However, lesion segmentation remains a challenge to state-of-the-art CNN-based algorithms due to the variance in scales and shapes. On the…
There has been exploding interest in embracing Transformer-based architectures for medical image segmentation. However, the lack of large-scale annotated medical datasets make achieving performances equivalent to those in natural images…
Convolutional neural networks (CNNs) have been successfully applied to medical image classification, segmentation, and related tasks. Among the many CNNs architectures, U-Net and its improved versions based are widely used and achieve…
Recent advance in 2D CNNs has revealed that large kernels are important. However, when directly applying large convolutional kernels in 3D CNNs, severe difficulties are met, where those successful module designs in 2D become surprisingly…
Cell imaging and analysis are fundamental to biomedical research because cells are the basic functional units of life. Among different cell-related analysis, cell counting and detection are widely used. In this paper, we focus on one common…
One of the essential tasks in medical image analysis is segmentation and accurate detection of borders. Lesion segmentation in skin images is an essential step in the computerized detection of skin cancer. However, many of the…
Convolutional Neural Networks have been the backbone of recent rapid progress in Single-Image Super-Resolution. However, existing networks are very deep with many network parameters, thus having a large memory footprint and being…
Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…
Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…
We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…
We present a method for skin lesion segmentation for the ISIC 2017 Skin Lesion Segmentation Challenge. Our approach is based on a Fully Convolutional Network architecture which is trained end to end, from scratch, on a limited dataset. Our…
The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…
Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…
The square kernel is a standard unit for contemporary CNNs, as it fits well on the tensor computation for convolution operation. However, the retinal ganglion cells in the biological visual system have approximately concentric receptive…
Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as…