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Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Prajol Shrestha , Mikhail Kulyabin , Aline Sindel , Hilde R. Pedersen , Stuart Gilson , Rigmor Baraas , Andreas Maier

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Skin lesions segmentation is an important step in the process of automated diagnosis of the skin melanoma. However, the accuracy of segmenting melanomas skin lesions is quite a challenging task due to less data for training, irregular…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Sabari Nathan , Priya Kansal

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Early detection of skin cancer relies on precise segmentation of dermoscopic images of skin lesions. However, this task is challenging due to the irregular shape of the lesion, the lack of sharp borders, and the presence of artefacts such…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Shahzaib Iqbal , Muhammad Zeeshan , Mehwish Mehmood , Tariq M. Khan , Imran Razzak

Medical image segmentation has seen significant improvements with transformer models, which excel in grasping far-reaching contexts and global contextual information. However, the increasing computational demands of these models,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Reza Azad , Leon Niggemeier , Michael Huttemann , Amirhossein Kazerouni , Ehsan Khodapanah Aghdam , Yury Velichko , Ulas Bagci , Dorit Merhof

Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Zhenqi He , Mathias Unberath , Jing Ke , Yiqing Shen

In the last few years, Deep Learning (DL) has been showing superior performance in different modalities of biomedical image analysis. Several DL architectures have been proposed for classification, segmentation, and detection tasks in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Md Zahangir Alom , Theus Aspiras , Tarek M. Taha , Vijayan K. Asari

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Recently, some large kernel convnets strike back with appealing performance and efficiency. However, given the square complexity of convolution, scaling up kernels can bring about an enormous amount of parameters and the proliferated…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Honghao Chen , Xiangxiang Chu , Yongjian Ren , Xin Zhao , Kaiqi Huang

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

Medical image segmentation is the technique that helps doctor view and has a precise diagnosis, particularly in Colorectal Cancer. Specifically, with the increase in cases, the diagnosis and identification need to be faster and more…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Trong-Hieu Nguyen Mau , Quoc-Huy Trinh , Nhat-Tan Bui , Minh-Triet Tran , Hai-Dang Nguyen

The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Yao Xue , Nilanjan Ray

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

Accurate segmentation of live cell images has broad applications in clinical and research contexts. Deep learning methods have been able to perform cell segmentations with high accuracy; however developing machine learning models to do this…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Mayur Bhandary , J. Patricio Reyes , Eylul Ertay , Aman Panda

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot