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In this paper, we consider a novel framework of positive-unlabeled data in which as positive data survival times are observed for subjects who have events during the observation time as positive data and as unlabeled data censoring times…

Methodology · Statistics 2020-11-30 Tomoki Toyabe , Yasuhiro Hasegawa , Takahiro Hoshino

Survival prediction is a major concern for cancer management. Deep survival models based on deep learning have been widely adopted to perform end-to-end survival prediction from medical images. Recent deep survival models achieved promising…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Mingyuan Meng , Bingxin Gu , Michael Fulham , Shaoli Song , Dagan Feng , Lei Bi , Jinman Kim

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

With the rapid advances in high-throughput sequencing technologies, the focus of survival analysis has shifted from examining clinical indicators to incorporating genomic profiles with pathological images. However, existing methods either…

Image and Video Processing · Electrical Eng. & Systems 2023-09-25 Fengtao Zhou , Hao Chen

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

A weakly-supervised learning framework named as complementary-label learning has been proposed recently, where each sample is equipped with a single complementary label that denotes one of the classes the sample does not belong to. However,…

Machine Learning · Statistics 2020-07-24 Yuzhou Cao , Shuqi Liu , Yitian Xu

A versatile medical image segmentation model applicable to images acquired with diverse equipment and protocols can facilitate model deployment and maintenance. However, building such a model typically demands a large, diverse, and fully…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Xiaoyang Chen , Hao Zheng , Yuemeng Li , Yuncong Ma , Liang Ma , Hongming Li , Yong Fan

Pixel-level vision tasks, such as semantic segmentation, require extensive and high-quality annotated data, which is costly to obtain. Semi-supervised semantic segmentation (SSSS) has emerged as a solution to alleviate the labeling burden…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Danhui Chen , Ziquan Liu , Chuxi Yang , Dan Wang , Yan Yan , Yi Xu , Xiangyang Ji

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

Methodology · Statistics 2026-01-12 Saku Suorsa , Aki Vehtari

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Combining multiple modalities carrying complementary information through multimodal learning (MML) has shown considerable benefits for diagnosing multiple pathologies. However, the robustness of multimodal models to missing modalities is…

Machine Learning · Computer Science 2024-07-31 Hava Chaptoukaev , Vincenzo Marcianó , Francesco Galati , Maria A. Zuluaga

Multimodal learning significantly benefits cancer survival prediction, especially the integration of pathological images and genomic data. Despite advantages of multimodal learning for cancer survival prediction, massive redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yilan Zhang , Yingxue Xu , Jianqi Chen , Fengying Xie , Hao Chen

Self-supervised learning is an efficient pre-training method for medical image analysis. However, current research is mostly confined to specific-modality data pre-training, consuming considerable time and resources without achieving…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Qi Wu , Yong Xia

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Deep learning has achieved unprecedented success in various object detection tasks with huge amounts of labeled data. However, obtaining large-scale annotations for medical images is extremely challenging due to the high demand of labour…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Zhizhong Chai , Luyang Luo , Huangjing Lin , Hao Chen , Anjia Han , Pheng-Ann Heng

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Semi-supervised learning, i.e. jointly learning from labeled and unlabeled samples, is an active research topic due to its key role on relaxing human supervision. In the context of image classification, recent advances to learn from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Eric Arazo , Diego Ortego , Paul Albert , Noel E. O'Connor , Kevin McGuinness

We present a conformal inference method for constructing lower prediction bounds for survival times from right-censored data, extending recent approaches designed for more restrictive type-I censoring scenarios. The proposed method imputes…

Methodology · Statistics 2025-05-26 Matteo Sesia , Vladimir Svetnik

Leveraging multimodal data, particularly the integration of whole-slide histology images (WSIs) and transcriptomic profiles, holds great promise for improving cancer survival prediction. However, excessive redundancy in multimodal data can…

Image and Video Processing · Electrical Eng. & Systems 2025-03-07 Hong Liu , Haosen Yang , Federica Eduati , Josien P. W. Pluim , Mitko Veta

Recent multi-modal face anti-spoofing (FAS) methods have investigated the potential of leveraging multiple modalities to distinguish live and spoof faces. However, pre-adapted multi-modal FAS models often fail to detect unseen attacks from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ming-Tsung Hsu , Fang-Yu Hsu , Yi-Ting Lin , Kai-Heng Chien , Jun-Ren Chen , Cheng-Hsiang Su , Yi-Chen Ou , Chiou-Ting Hsu , Pei-Kai Huang