Related papers: scGHSOM: Hierarchical clustering and visualization…
Serous borderline ovarian tumor (SBOT) and high-grade serous ovarian cancer (HGSOC) are two distinct subtypes of epithelial ovarian tumors, with markedly different biologic background, behavior, prognosis, and treatment. However, the…
Semi-supervised clustering techniques have emerged as valuable tools for leveraging prior information in the form of constraints to improve the quality of clustering outcomes. Despite the proliferation of such methods, the ability to…
Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…
Self-supervised heterogeneous graph learning (SHGL) has shown promising potential in diverse scenarios. However, while existing SHGL methods share a similar essential with clustering approaches, they encounter two significant limitations:…
The COSMOS-Web survey, with its unparalleled combination of multiband data, notably, near-infrared imaging from JWST's NIRCam (F115W, F150W, F277W, and F444W), provides a transformative dataset down to $\sim28$ mag (F444W) for studying…
Practitioners from many disciplines (e.g., political science) use expert-crafted taxonomies to make sense of large, unlabeled corpora. In this work, we study Seeded Hierarchical Clustering (SHC): the task of automatically fitting unlabeled…
Self organizing maps (SOMs) are widely-used for unsupervised classification. For this application, they must be combined with some partitioning scheme that can identify boundaries between distinct regions in the maps they produce. We…
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…
Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…
Hyperspectral image (HSI) clustering groups pixels into clusters without labeled data, which is an important yet challenging task. For large-scale HSIs, most methods rely on superpixel segmentation and perform superpixel-level clustering…
Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…
We present an application of unsupervised machine learning - the self-organised map (SOM) - as a tool for visualising, exploring and mining the catalogues of large astronomical surveys. Self-organisation culminates in a low-resolution…
In high-performance computing (HPC) environments, system monitoring data is often unlabeled and high-dimensional, making it difficult to reliably detect and understand anomalous computing nodes. The growing scale and dimensionality of the…
Spectral clustering is a powerful tool for unsupervised data analysis. In this paper, we propose a context-aware hypergraph similarity measure (CAHSM), which leads to robust spectral clustering in the case of noisy data. We construct three…
We uncover that current objective-based Divisive Hierarchical Clustering (DHC) methods produce a dendrogram that does not have three desired properties i.e., no unwarranted splitting, group similar clusters into a same subset, ground-truth…
Subspace clustering is a powerful unsupervised approach for hyperspectral image (HSI) analysis, but its high computational and memory costs limit scalability. Superpixel segmentation can improve efficiency by reducing the number of data…
In several environmental applications data are functions of time, essentially con- tinuous, observed and recorded discretely, and spatially correlated. Most of the methods for analyzing such data are extensions of spatial statistical tools…
This work describes the implementation and application of a correlation determination method based on Self Organizing Maps and Bayesian Inference (SOMBI). SOMBI aims to automatically identify relations between different observed parameters…
In this paper, we consider feature screening for ultrahigh dimensional clustering analyses. Based on the observation that the marginal distribution of any given feature is a mixture of its conditional distributions in different clusters, we…
Clustering and visualizing high-dimensional (HD) data are important tasks in a variety of fields. For example, in bioinformatics, they are crucial for analyses of single-cell data such as mass cytometry (CyTOF) data. Some of the most…