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Current multimodal fusion approaches in computational oncology primarily focus on integrating multi-gigapixel histology whole slide images (WSIs) with genomic or transcriptomic data, demonstrating improved survival prediction. We…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Manahil Raza , Ayesha Azam , Talha Qaiser , Nasir Rajpoot

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Gabriel Jimenez , Daniel Racoceanu

Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are primarily limited to a small set of modalities and tasks, which hinders the development of large-scale…

Machine Learning · Computer Science 2025-03-21 Wei Dai , Peilin Chen , Malinda Lu , Daniel Li , Haowen Wei , Hejie Cui , Paul Pu Liang

Mitotic activity is an important feature for grading several cancer types. Counting mitotic figures (MFs) is a time-consuming, laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and…

Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Chengsheng Zhang , Linhao Qu , Xiaoyu Liu , Zhijian Song

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Spread through air spaces (STAS) represents a newly identified aggressive pattern in lung cancer, which is known to be associated with adverse prognostic factors and complex pathological features. Pathologists currently rely on time…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Liangrui Pan , Xiaoyu Li , Yutao Dou , Qiya Song , Jiadi Luo , Qingchun Liang , Shaoliang Peng

Developing computational pathology models is essential for reducing manual tissue typing from whole slide images, transferring knowledge from the source domain to an unlabeled, shifted target domain, and identifying unseen categories. We…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Guillaume Vray , Devavrat Tomar , Jean-Philippe Thiran , Behzad Bozorgtabar

Whole slide image (WSI) analysis is gaining prominence within the medical imaging field. Recent advances in pathology foundation models have shown the potential to extract powerful feature representations from WSIs for downstream tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yanyan Huang , Weiqin Zhao , Yihang Chen , Yu Fu , Lequan Yu

CLIP models pretrained on natural images with billion-scale image-text pairs have demonstrated impressive capabilities in zero-shot classification, cross-modal retrieval, and open-ended visual answering. However, transferring this success…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Shansong Wang , Zhecheng Jin , Mingzhe Hu , Mojtaba Safari , Feng Zhao , Chih-Wei Chang , Richard LJ Qiu , Justin Roper , David S. Yu , Xiaofeng Yang

Advancing AI in computational pathology requires large, high-quality, and diverse datasets, yet existing public datasets are often limited in organ diversity, class coverage, or annotation quality. To bridge this gap, we introduce SPIDER…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

In this work we show preliminary results of deep multi-task learning in the area of computational pathology. We combine 11 tasks ranging from patch-wise oral cancer classification, one of the most prevalent cancers in the developing world,…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Jevgenij Gamper , Navid Alemi Kooohbanani , Nasir Rajpoot

Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…

Accurate prediction of placental diseases via whole slide images (WSIs) is critical for preventing severe maternal and fetal complications. However, WSI analysis presents significant computational challenges due to the massive data volume.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Hang Guo , Qing Zhang , Zixuan Gao , Siyuan Yang , Shulin Peng , Xiang Tao , Ting Yu , Yan Wang , Qingli Li

Forensic pathology is critical in analyzing death manner and time from the microscopic aspect to assist in the establishment of reliable factual bases for criminal investigation. In practice, even the manual differentiation between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Chen Shen , Jun Zhang , Xinggong Liang , Zeyi Hao , Kehan Li , Fan Wang , Zhenyuan Wang , Chunfeng Lian

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva