English
Related papers

Related papers: A Multimodal Knowledge-enhanced Whole-slide Pathol…

200 papers

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Penghao Zhang , Jingru Guo , Tao Cheng , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Sheng Wang , Ruiming Wu , Charles Herndon , Yihang Liu , Shunsuke Koga , Jeanne Shen , Zhi Huang

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Surface prediction and completion have been widely studied in various applications. Recently, research in surface completion has evolved from small objects to complex large-scale scenes. As a result, researchers have begun increasing the…

Robotics · Computer Science 2024-03-19 Guiyong Zheng , Jinqi Jiang , Chen Feng , Shaojie Shen , Boyu Zhou

Intraoperative pathology is pivotal to precision surgery, yet its clinical impact is constrained by diagnostic complexity and the limited availability of high-quality frozen-section data. While computational pathology has made significant…

The emergence of large multimodal models has unlocked remarkable potential in AI, particularly in pathology. However, the lack of specialized, high-quality benchmark impeded their development and precise evaluation. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuxuan Sun , Hao Wu , Chenglu Zhu , Sunyi Zheng , Qizi Chen , Kai Zhang , Yunlong Zhang , Dan Wan , Xiaoxiao Lan , Mengyue Zheng , Jingxiong Li , Xinheng Lyu , Tao Lin , Lin Yang

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders producing biologically grounded representations on both sides of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Amaya Gallagher-Syed , Costantino Pitzalis , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

Due to the increasing workload of pathologists, the need for automation to support diagnostic tasks and quantitative biomarker evaluation is becoming more and more apparent. Foundation models have the potential to improve generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Till Nicke , Jan Raphael Schaefer , Henning Hoefener , Friedrich Feuerhake , Dorit Merhof , Fabian Kiessling , Johannes Lotz

Hematoxylin- and eosin (H&E) stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-based methods in computational pathology enabled the prediction of biomarkers directly…

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly…

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood