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Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Aspect-based sentiment analysis (ABSA) identifies sentiment information related to specific aspects and provides deeper market insights to businesses and organizations. With the emergence of large language models (LMs), recent studies have…

Computation and Language · Computer Science 2024-05-30 Guangmin Zheng , Jin Wang , Liang-Chih Yu , Xuejie Zhang

In recent years, Automated Program Repair (APR) has been extensively studied in academia and even drawn wide attention from industry. However, APR techniques can be extremely time consuming since (1) a large number of patches can be…

Software Engineering · Computer Science 2024-07-03 Yiling Lou , Jun Yang , Samuel Benton , Dan Hao , Lin Tan , Zhenpeng Chen , Lu Zhang , Lingming Zhang

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

Methodology · Statistics 2026-03-03 Harlan Campbell , Jeroen P. Jansen

We present the parallel and interacting stochastic approximation annealing (PISAA) algorithm, a stochastic simulation procedure for global optimisation, that extends and improves the stochastic approximation annealing (SAA) by using…

Computation · Statistics 2015-08-21 Georgios Karagiannis , Bledar A. Konomi , Guang Lin , Faming Liang

We consider the problem of estimating the average treatment effect (ATE) when both randomized control trial (RCT) data and external real-world data (RWD) are available. We decompose the ATE estimand as the difference between a pooled-ATE…

Methodology · Statistics 2025-01-22 Mark van der Laan , Sky Qiu , Jens Magelund Tarp , Lars van der Laan

We study the assessment of the accuracy of heterogeneous treatment effect (HTE) estimation, where the HTE is not directly observable so standard computation of prediction errors is not applicable. To tackle the difficulty, we propose an…

Methodology · Statistics 2020-03-10 Zijun Gao , Trevor Hastie , Robert Tibshirani

The synthetic control method (SCM) is a popular approach for estimating the impact of a treatment on a single unit in panel data settings. The "synthetic control" is a weighted average of control units that balances the treated unit's…

Methodology · Statistics 2020-07-24 Eli Ben-Michael , Avi Feller , Jesse Rothstein

Automatic prompt engineering (APE) rewrites prompts to improve downstream task performance, but existing APE loops treat the optimizer itself as a fixed pipeline. We port the code-as-action paradigm of CodeAct (Wang et al., 2024a) to APE…

Computation and Language · Computer Science 2026-05-27 Mengyin Lu , Cong Feng , Huimin Han , Guangming Lu , Yu Sun , Xiaonan Ding , Shihui Long , Fengyi Li , Tanvi Motwani

Automatic reviewing helps handle a large volume of papers, provides early feedback and quality control, reduces bias, and allows the analysis of trends. We evaluate the alignment of automatic paper reviews with human reviews using an arena…

In the context of a binary treatment, matching is a well-established approach in causal inference. However, in the context of a continuous treatment or exposure, matching is still underdeveloped. We propose an innovative matching approach…

Promoting healthy lifestyle behaviors remains a major public health concern, particularly due to their crucial role in preventing chronic conditions such as cancer, heart disease, and type 2 diabetes. Mobile health applications present a…

Machine Learning · Computer Science 2024-05-24 Aishwarya Mandyam , Matthew Jörke , William Denton , Barbara E. Engelhardt , Emma Brunskill

Covariate adjustment is a ubiquitous method used to estimate the average treatment effect (ATE) from observational data. Assuming a known graphical structure of the data generating model, recent results give graphical criteria for optimal…

Statistics Theory · Mathematics 2025-12-08 Alexander Mangulad Christgau , Anton Rask Lundborg , Niels Richard Hansen

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

Methodology · Statistics 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

Diverse classes of proteins function through large-scale conformational changes; sophisticated enhanced sampling methods have been proposed to generate these macromolecular transition paths. As such paths are curves in a high-dimensional…

Quantitative Methods · Quantitative Biology 2015-10-27 Sean L. Seyler , Avishek Kumar , Michael F. Thorpe , Oliver Beckstein

A/B testing, a widely used form of Randomized Controlled Trial (RCT), is a fundamental tool in business data analysis and experimental design. However, despite its intent to maintain randomness, A/B testing often faces challenges that…

Methodology · Statistics 2024-08-13 Zihao Zheng , Carol Liu

Post-traumatic stress disorder (PTSD) is a significant mental health challenge that affects individuals exposed to traumatic events. Early detection and effective intervention for PTSD are crucial, as it can lead to long-term psychological…

Machine Learning · Computer Science 2024-11-19 Ayesha Siddiqua , Atib Mohammad Oni , Abu Saleh Musa Miah , Jungpil Shin

The development of rigorous quality assessment model relies on the collection of reliable subjective data, where the perceived quality of visual multimedia is rated by the human observers. Different subjective assessment protocols can be…

Artificial Intelligence · Computer Science 2020-10-02 Suiyi Ling , Jing Li , Anne Flore Perrin , Zhi Li , Lukáš Krasula , Patrick Le Callet

Recommender systems (RS) work effective at alleviating information overload and matching user interests in various web-scale applications. Most RS retrieve the user's favorite candidates and then rank them by the rating scores in the greedy…

Information Retrieval · Computer Science 2021-04-05 Yufei Feng , Yu Gong , Fei Sun , Junfeng Ge , Wenwu Ou

We extend methods for finite-sample inference about the average treatment effect (ATE) in randomized experiments with binary outcomes to accommodate stratification (blocking). We present three valid methods that differ in their…

Methodology · Statistics 2025-08-07 Jiaxun Li , Jacob Spertus , Philip B. Stark