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Understanding cognitive flexibility and task-switching mechanisms in neural systems requires biologically plausible computational models. This tutorial presents a step-by-step approach to constructing a spiking neural network (SNN) that…

Neurons and Cognition · Quantitative Biology 2025-03-07 Ashwin Viswanathan Kannan , Madhumitha Ganesan

Modeling the interplay between external stimuli and internal neural representations is a pivotal research area for Brain-Computer Interfaces (BCIs). A major limitation of prior work is the prevailing paradigm of specialized, single-task…

Artificial Intelligence · Computer Science 2026-05-29 Yizhuo Lu , Changde Du , Qingyu Shi , Hang Chen , Jie Peng , Liuyun Jiang , Shuangchen Zhao , Huiguang He

Deep learning associated with neurological signals is poised to drive major advancements in diverse fields such as medical diagnostics, neurorehabilitation, and brain-computer interfaces. The challenge in harnessing the full potential of…

Signal Processing · Electrical Eng. & Systems 2024-07-08 Di Wu , Siyuan Li , Jie Yang , Mohamad Sawan

Masked Image Modeling (MIM) has recently been established as a potent pre-training paradigm. A pretext task is constructed by masking patches in an input image, and this masked content is then predicted by a neural network using visible…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Philippe Weinzaepfel , Vincent Leroy , Thomas Lucas , Romain Brégier , Yohann Cabon , Vaibhav Arora , Leonid Antsfeld , Boris Chidlovskii , Gabriela Csurka , Jérôme Revaud

Multi-task learning (MTL) has received considerable attention, and numerous deep learning applications benefit from MTL with multiple objectives. However, constructing multiple related tasks is difficult, and sometimes only a single task is…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tao Gui , Lizhi Qing , Qi Zhang , Jiacheng Ye , Hang Yan , Zichu Fei , Xuanjing Huang

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Neural dynamics underlie behaviors from memory to sleep, yet identifying mechanisms for higher-order phenomena (e.g., social interaction) is experimentally challenging. Existing whole-brain models often fail to scale to single-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Sam Fatehmanesh Vegas , Matt Thomson , James Gornet , David Prober

Semi-supervised learning via learning from limited quantities of labeled data has been investigated as an alternative to supervised counterparts. Maximizing knowledge gains from copious unlabeled data benefit semi-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Ayaan Haque , Abdullah-Al-Zubaer Imran , Adam Wang , Demetri Terzopoulos

Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jiaxing Xu , Jingying Ma , Xin Lin , Yuxiao Liu , Kai He , Qika Lin , Yiping Ke , Yang Li , Dinggang Shen , Mengling Feng

Providing the neurobiological basis of information processing in higher animals, spiking neural networks must be able to learn a variety of complicated computations, including the generation of appropriate, possibly delayed reactions to…

Neurons and Cognition · Quantitative Biology 2016-06-30 Dominik Thalmeier , Marvin Uhlmann , Hilbert J. Kappen , Raoul-Martin Memmesheimer

Neural population activity often exhibits regime-dependent non-stationarity in the form of switching dynamics. Learning accurate switching dynamical system models can reveal how behavior is encoded in neural activity. Existing switching…

Machine Learning · Computer Science 2025-12-16 DongKyu Kim , Han-Lin Hsieh , Maryam M. Shanechi

We discover a robust self-supervised strategy tailored towards molecular representations for generative masked language models through a series of tailored, in-depth ablations. Using this pre-training strategy, we train BARTSmiles, a…

Cytoarchitectonic parcellations of the human brain serve as anatomical references in multimodal atlas frameworks. They are based on analysis of cell-body stained histological sections and the identification of borders between brain areas.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Hannah Spitzer , Kai Kiwitz , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Reaching a global view of brain organization requires assembling evidence on widely different mental processes and mechanisms. The variety of human neuroscience concepts and terminology poses a fundamental challenge to relating brain…

Quantitative Methods · Quantitative Biology 2020-02-24 Jérôme Dockès , Russell Poldrack , Romain Primet , Hande Gözükan , Tal Yarkoni , Fabian Suchanek , Bertrand Thirion , Gaël Varoquaux

It takes several years for the developing brain of a baby to fully master word repetition-the task of hearing a word and repeating it aloud. Repeating a new word, such as from a new language, can be a challenging task also for adults.…

Computation and Language · Computer Science 2025-06-17 Daniel Dager , Robin Sobczyk , Emmanuel Chemla , Yair Lakretz

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

Pretrained Transformer based models finetuned on domain specific corpora have changed the landscape of NLP. However, training or fine-tuning these models for individual tasks can be time consuming and resource intensive. Thus, a lot of…

Training a single model on multiple input domains and/or output tasks allows for compressing information from multiple sources into a unified backbone hence improves model efficiency. It also enables potential positive knowledge transfer…

Machine Learning · Computer Science 2023-10-16 Amelie Royer , Tijmen Blankevoort , Babak Ehteshami Bejnordi

Advances in neural recording present increasing opportunities to study neural activity in unprecedented detail. Latent variable models (LVMs) are promising tools for analyzing this rich activity across diverse neural systems and behaviors,…