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Related papers: A String-Graph Approach to Molecular Geometry

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Molecules are frequently represented as graphs, but the underlying 3D molecular geometry (the locations of the atoms) ultimately determines most molecular properties. However, most molecules are not static and at room temperature adopt a…

Chemical Physics · Physics 2023-06-14 Kirk Swanson , Jake Williams , Eric Jonas

The graph neural network (GNN) has been a powerful deep-learning tool in chemistry domain, due to its close connection with molecular graphs. Most GNN models collect and update atom and molecule features from the fed atom (and, in some…

Chemical Physics · Physics 2022-03-18 Yeji Kim , Yoonho Jeong , Jihoo Kim , Eok Kyun Lee , Won June Kim , Insung S. Choi

Procuring expressive molecular representations underpins AI-driven molecule design and scientific discovery. The research mainly focuses on atom-level homogeneous molecular graphs, ignoring the rich information in subgraphs or motifs.…

Quantitative Methods · Quantitative Biology 2023-01-10 Fang Wu , Dragomir Radev , Stan Z. Li

Topological analysis of the magnetic field in simulated plasmas allows the study of various physical phenomena in a wide range of settings. One such application is magnetic reconnection, a phenomenon related to the dynamics of the magnetic…

The study of electronic transitions within a molecule connected to the absorption or emission of light is a common task in the process of the design of new materials. The transitions are complex quantum mechanical processes and a detailed…

Human-Computer Interaction · Computer Science 2021-06-03 Talha Bin Masood , Signe Sidwall Thygesen , Mathieu Linares , Alexei I. Abrikosov , Vijay Natarajan , Ingrid Hotz

Developing a bottom-up (molecular) theory for the electromechanical response of aperiodic materials is a prerequisite for understanding the piezoelectric properties of systems such as nanoparticles, (non-crystalline) polymers, or…

Chemical Physics · Physics 2017-07-25 Keith A. Werling , Geoffrey R. Hutchison , Daniel S. Lambrecht

The anchoring of the molecule to an electrode is known to be a key factor in single-molecule spintronics experiments. Likewise, a relaxation down to the most stable geometry is a critical step in theoretical simulations of transport through…

Mesoscale and Nanoscale Physics · Physics 2019-06-18 Silvia Giménez-Santamarina , Salvador Cardona-Serra , Alejandro Gaita-Ariño

The application of language models (LMs) to molecular structure generation using line notations such as SMILES and SELFIES has been well-established in the field of cheminformatics. However, extending these models to generate 3D molecular…

Machine Learning · Computer Science 2024-12-03 Kaiyuan Gao , Yusong Wang , Haoxiang Guan , Zun Wang , Qizhi Pei , John E. Hopcroft , Kun He , Lijun Wu

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

The simulation of the physical movement of multi-body systems at an atomistic level, with forces calculated from a quantum mechanical description of the electrons, motivates a graph partitioning problem studied in this article. Several…

We introduce a new model of proteins, which extends and enhances the traditional graphical representation by associating a combinatorial object called a fatgraph to any protein based upon its intrinsic geometry. Fatgraphs can easily be…

Biomolecules · Quantitative Biology 2009-05-30 R. C. Penner , Michael Knudsen , Carsten Wiuf , Joergen Ellegaard Andersen

A string-theoretic structure of the standard model is defined having a 4-D quantum gravity metric consistent with topological and algebraic first principles. Unique topological diagrams of string states, strong and weak interactions and…

General Physics · Physics 2007-05-23 Wayne R. Lundberg

Geometric graphs are a special kind of graph with geometric features, which are vital to model many scientific problems. Unlike generic graphs, geometric graphs often exhibit physical symmetries of translations, rotations, and reflections,…

Observing the individual building blocks of matter is one of the primary goals of microscopy. The invention of the scanning tunneling microscope [1] revolutionized experimental surface science in that atomic-scale features on a solid-state…

Materials Science · Physics 2008-08-04 Jannik C. Meyer , C. O. Girit , M. F. Crommie , A. Zettl

Determining the complexity of molecules has important applications from molecular design to understanding the history of the process that led to the formation of the molecule. Currently, it is not possible to experimentally determine,…

Molecular representation learning is pivotal in predicting molecular properties and advancing drug design. Traditional methodologies, which predominantly rely on homogeneous graph encoding, are limited by their inability to integrate…

Machine Learning · Computer Science 2025-03-24 Mukun Chen , Jia Wu , Shirui Pan , Fu Lin , Bo Du , Xiuwen Gong , Wenbin Hu

Time-resolved investigations of ultrafast electronic and molecular dynamics were not possible until recently. The typical time scale of these processes is in the picosecond to attosecond realm. The tremendous technological progress in…

Atomic Physics · Physics 2013-05-14 Stefan Pabst

Molecular Mechanics describes molecules as particle configurations interacting via classical potentials. These {\it configurational energies} usually consist of the sum of different phenomenological terms which are tailored to the…

Materials Science · Physics 2017-01-11 Manuel Friedrich , Paolo Piovano , Ulisse Stefanelli

Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

Methodology · Statistics 2016-06-09 Mathias Drton , Marloes H. Maathuis