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Domain Adaptation (DA), the process of effectively adapting task models learned on one domain, the source, to other related but distinct domains, the targets, with no or minimal retraining, is typically accomplished using the process of…

Computer Vision and Pattern Recognition · Computer Science 2019-09-30 Behnam Gholami , Pritish Sahu , Minyoung Kim , Vladimir Pavlovic

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

Skin cancer is the most common cancer type. Usually, patients with suspicion of cancer are treated by doctors without any aided visual inspection. At this point, dermoscopy has become a suitable tool to support physicians in their…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-25 Yongli Mou , Sascha Welten , Yeliz Ucer Yediel , Toralf Kirsten , Oya Deniz Beyan

Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Harshal Nishar , Nikhil Chavanke , Nitin Singhal

In this work, we propose a mutual information (MI) based unsupervised domain adaptation (UDA) method for the cross-domain nuclei segmentation. Nuclei vary substantially in structure and appearances across different cancer types, leading to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Yash Sharma , Sana Syed , Donald E. Brown

This study introduces a novel data augmentation technique, ADLDA, aimed at mitigating the negative impact of data distribution shifts caused by the data augmentation process in computer vision task. ADLDA partitions augmented data into…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Haonan Wang

Label variability is a major challenge for prostate lesion segmentation. In multi-site datasets, annotations often reflect centre-specific contouring protocols, causing segmentation networks to overfit to local styles and generalise poorly…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Wen Yan , Yipei Wang , Shiqi Huang , Natasha Thorley , Mark Emberton , Vasilis Stavrinides , Yipeng Hu , Dean Barratt

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Shahabedin Nabavi , Kian Anvari Hamedani , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi

Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Xianxu Hou , Jingxin Liu , Bolei Xu , Bozhi Liu , Xin Chen , Mohammad Ilyas , Ian Ellis , Jon Garibaldi , Guoping Qiu

Magnetic Resonance Imaging (MRI) is considered the gold standard of medical imaging because of the excellent soft-tissue contrast exhibited in the images reconstructed by the MRI pipeline, which in-turn enables the human radiologist to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Divyam Madaan , Daniel Sodickson , Kyunghyun Cho , Sumit Chopra

Modern deep neural networks can achieve high accuracy when the training distribution and test distribution are identically distributed, but this assumption is frequently violated in practice. When the train and test distributions are…

Machine Learning · Statistics 2020-02-18 Dan Hendrycks , Norman Mu , Ekin D. Cubuk , Barret Zoph , Justin Gilmer , Balaji Lakshminarayanan

A key challenge in cancer immunotherapy biomarker research is quantification of pattern changes in microscopic whole slide images of tumor biopsies. Different cell types tend to migrate into various tissue compartments and form variable…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Amal Lahiani , Jacob Gildenblat , Irina Klaman , Nassir Navab , Eldad Klaiman

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

The limited ability of Convolutional Neural Networks to generalize to images from previously unseen domains is a major limitation, in particular, for safety-critical clinical tasks such as dermoscopic skin cancer classification. In order to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Katharina Fogelberg , Sireesha Chamarthi , Roman C. Maron , Julia Niebling , Titus J. Brinker

The color appearance of a pathological image is highly related to the imaging protocols, the proportion of different dyes, and the scanning devices. Computer-aided diagnostic systems may deteriorate when facing these color-variant…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Zheng Chen

Emerging diseases present challenges in symptom recognition and timely clinical intervention due to limited available information. An effective prognostic model could assist physicians in making accurate diagnoses and designing personalized…

Machine Learning · Computer Science 2025-02-12 Zhongji Zhang , Yuhang Wang , Yinghao Zhu , Xinyu Ma , Yasha Wang , Junyi Gao , Liantao Ma , Wen Tang , Xiaoyun Zhang , Ling Wang

An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…