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Previous research has shown a clear relationship between sleep and memory, examining the impact of sleep deprivation on key cognitive processes over very short durations or in special populations. Here, we show, in a longitudinal 16 week…

A method for the quantitative assessment of spatio-temporal structuring of brain activity is presented. This approach is employed in a longitudinal case study of a child with frontal lobe epilepsy (FLE) and tested against an age-matched…

Medical Physics · Physics 2009-05-26 W. Bunk , T. Aschenbrenner , G. Kluger , S. Springer

With rapid development of techniques to measure brain activity and structure, statistical methods for analyzing modern brain-imaging play an important role in the advancement of science. Imaging data that measure brain function are usually…

Methodology · Statistics 2023-01-05 Haoyi Fu , Lu Tang , Ori Rosen , Alison E. Hipwell , Theodore J. Huppert , Robert T. Krafty

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…

Neurons and Cognition · Quantitative Biology 2014-03-26 Roberta Russo , Hans J Herrmann , Lucilla de Arcangelis

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

One of the most contested questions about human behaviour is whether there are inherent sex or gender differences in the formation and maintenance of social bonds. On one hand, female and male brains are structurally almost identical, and…

Social and Information Networks · Computer Science 2022-03-08 Tamas David-Barrett

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Liyue Shen , Katie Shpanskaya , Edward Lee , Emily McKenna , Maryam Maleki , Quin Lu , Safwan Halabi , John Pauly , Kristen Yeom

Infants with a variety of complications at or before birth are classified as being at risk for developmental delays (AR). As they grow older, they are followed by healthcare providers in an effort to discern whether they are on a typical or…

Machine Learning · Computer Science 2018-10-16 David Goodfellow , Ruoyu Zhi , Rebecca Funke , Jose Carlos Pulido , Maja Mataric , Beth A. Smith

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Bias in medical AI is often framed as a problem of representation. However, in image-based tasks such as fetal ultrasound, performance disparities can arise even when representation is adequate, because predictive accuracy depends strongly…

Brain development during adolescence is marked by substantial changes in brain structure and function, leading to a stable network topology in adulthood. However, most prior work has examined the data through the lens of brain areas…

Quantitative Methods · Quantitative Biology 2016-12-26 Shi Gu , Muzhi Yang , John D. Medaglia , Ruben C. Gur , Raquel E. Gur , Theodore D. Satterthwaite , Danielle S. Bassett

Understanding the temporal dynamics of functional brain connectivity is important for addressing various questions in network neuroscience, such as how connectivity affects cognition and changes with disease. A fundamental challenge is to…

Methodology · Statistics 2025-12-02 Hester Huijsdens , Linda Geerligs , Max Hinne

Objective: Longitudinal neuroimaging studies have demonstrated that adolescence is the crucial developmental epoch of continued brain growth and change. A large number of researchers dedicate to uncovering the mechanisms about brain…

Neurons and Cognition · Quantitative Biology 2019-06-19 Junqi Wang , Li Xiao , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

In the analysis of binary longitudinal data, it is of interest to model a dynamic relationship between a response and covariates as a function of time, while also investigating similar patterns of time-dependent interactions. We present a…

Methodology · Statistics 2023-04-11 Jinwon Sohn , Seonghyun Jeong , Young Min Cho , Taeyoung Park

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

Neurons and Cognition · Quantitative Biology 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

The extent of intra-individual and inter-individual variability is an important factor in determining the statistical, and hence possibly clinical, significance of observed differences in the EEG. This study investigates the changes in…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Christopher J. Rennie , Peter A. Robinson

Sensory neurons often have variable responses to repeated presentations of the same stimulus, which can significantly degrade the stimulus information contained in those responses. This information can in principle be preserved if…

Neurons and Cognition · Quantitative Biology 2019-04-24 Matthew R Whiteway , Karolina Socha , Vincent Bonin , Daniel A Butts

Vocal responses from caregivers are believed to promote more frequent and more advanced infant vocalizations. However, studies that examine this relationship typically do not account for the fact that infant and adult vocalizations are…

Neurons and Cognition · Quantitative Biology 2025-05-21 VPS Ritwika , Sara Schneider , Lukas D. Lopez , Jeffrey Mai , Ajay Gopinathan , Christopher T. Kello , Anne S. Warlaumont