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The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

We study how modularity of the human brain changes as children develop into adults. Theory suggests that modularity can enhance the response function of a networked system subject to changing external stimuli. Thus, greater cognitive…

Neurons and Cognition · Quantitative Biology 2015-01-29 Man Chen , Michael W. Deem

Study Objectives: Fetal sleep is a vital yet underexplored aspect of prenatal neurodevelopment. Its cyclic organization reflects the maturation of central neural circuits, and disturbances in these patterns may offer some of the earliest…

Neurons and Cognition · Quantitative Biology 2026-01-19 Weitao Tang , Johann Vargas-Calixto , Nasim Katebi , Robert Galinsky , Gari D. Clifford , Faezeh Marzbanrad

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

Preterm newborns undergo various stresses that may materialize as learning problems at school-age. Sleep staging of the Electroencephalogram (EEG), followed by prediction of their brain-age from these sleep states can quantify deviations…

Machine Learning · Statistics 2018-09-20 Kirubin Pillay , Maarten De Vos

Recently we developed a novel method for assessing the hierarchical modularity of functional brain networks - the probability associated community estimation(PACE). The PACE algorithm is unique in that it permits a dual formulation, thus…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sean D. Conrin , Liang Zhan , Zachery D. Morrissey , Mengqi Xing , Angus Forbes , Pauline Maki , Mohammed R. Milad , Olusola Ajilore , Alex D. Leow

Infant sleep is critical to brain and behavioral development. Prior studies on infant sleep/wake classification have been largely limited to reliance on expensive and burdensome polysomnography (PSG) tests in the laboratory or wearable…

Multimedia · Computer Science 2023-06-29 Kai Chieh Chang , Mark Hasegawa-Johnson , Nancy L. McElwain , Bashima Islam

Exploring the developing brain is a major issue in understanding what enables children to acquire amazing abilities, and how early disruptions can lead to a wide range of neurodevelopmental disorders. MRI plays a key role here by providing…

Neurons and Cognition · Quantitative Biology 2024-01-01 Jessica Dubois

The methodology of Bayesian Model Averaging (BMA) is applied for assessment of newborn brain maturity from sleep EEG. In theory this methodology provides the most accurate assessments of uncertainty in decisions. However, the existing BMA…

Artificial Intelligence · Computer Science 2010-02-25 L. Jakaite , V. Schetinin , C. Maple

Converging evidence indicates that the heterogeneity of cognitive profiles may arise through detectable alternations in brain functions. Particularly, brain functional connectivity, measured under resting and cognitive states, characterizes…

Applications · Statistics 2023-02-22 Tianqi Chen , Chichun Tan , Hongyu Zhao , Todd Constable , Sarah Yip , Yize Zhao

The human brain is organized into large-scale functional modules that have been shown to evolve in childhood and adolescence. However, it remains unknown whether structural brain networks are similarly refined during development,…

This article presents a comprehensive analysis of the different tests proposed in the recent ChildCI framework, proving its potential for generating a better understanding of children's neuromotor and cognitive development along time, as…

Human-Computer Interaction · Computer Science 2024-03-25 Juan Carlos Ruiz-Garcia , Ruben Tolosana , Ruben Vera-Rodriguez , Julian Fierrez , Jaime Herreros-Rodriguez

Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

Neurons and Cognition · Quantitative Biology 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

In cognitive network neuroscience, the connectivity and community structure of the brain network is related to cognition. Much of this research has focused on two measures of connectivity - modularity and flexibility - which frequently have…

Neurons and Cognition · Quantitative Biology 2017-11-28 Aurora I. Ramos-Nuñez , Simon Fischer-Baum , Randi Martin , Qiuhai Yue , Fengdan Ye , Michael W. Deem

The statistical analysis of group studies in neuroscience is particularly challenging due to the complex spatio-temporal nature of the data, its multiple levels and the inter-individual variability in brain responses. In this respect,…

Methodology · Statistics 2025-05-15 Nicolò Margaritella , Vanda Inácio , Ruth King

Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior. These two attributes -- flexibility and selection -- must…

Neurons and Cognition · Quantitative Biology 2013-06-28 Danielle S. Bassett , Nicholas F. Wymbs , Mason A. Porter , Peter J. Mucha , Jean M. Carlson , Scott T. Grafton

Various brain functions that are necessary to maintain life activities materialize through the interaction of countless neurons. Therefore, it is important to analyze functional neuronal network. To elucidate the mechanism of brain…

Neurons and Cognition · Quantitative Biology 2023-06-29 Shun Kimura , Koujin Takeda

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Executive function emerges late in development and displays different developmental trends in males and females. Sex differences in executive function in youth have been linked to vulnerability to psychopathology as well as to behaviors…

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo
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