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Collateral circulation results from specialized anastomotic channels which are capable of providing oxygenated blood to regions with compromised blood flow caused by ischemic injuries. The quality of collateral circulation has been…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Giles Tetteh , Fernando Navarro , Johannes Paetzold , Jan Kirschke , Claus Zimmer , Bjoern H. Menze

We propose a topological framework to study the evolution of Alzheimer's disease, the most common neurodegenerative disease. The modeling of this disease starts with the representation of the brain connectivity as a graph and the seeding of…

Neurons and Cognition · Quantitative Biology 2023-09-20 Christian Goodbrake , David Beers , Travis B. Thompson , Heather A. Harrington , Alain Goriely

Despite the enormous success of graph neural networks (GNNs), most existing GNNs can only be applicable to undirected graphs where relationships among connected nodes are two-way symmetric (i.e., information can be passed back and forth).…

Machine Learning · Computer Science 2021-10-15 Zhuo Tan , Bin Liu , Guosheng Yin

In the present work, we use information theory to understand the empirical convergence rate of tractography, a widely-used approach to reconstruct anatomical fiber pathways in the living brain. Based on diffusion MRI data, tractography is…

Quantitative Methods · Quantitative Biology 2018-06-13 Daniel Moyer , Paul M. Thompson , Greg Ver Steeg

How neural networks in the human brain represent commonsense knowledge, and complete related reasoning tasks is an important research topic in neuroscience, cognitive science, psychology, and artificial intelligence. Although the…

Neural and Evolutionary Computing · Computer Science 2022-07-13 Hongjian Fang , Yi Zeng , Jianbo Tang , Yuwei Wang , Yao Liang , Xin Liu

Stroke is a significant cause of mortality and morbidity, necessitating early predictive strategies to minimize risks. Traditional methods for evaluating patients, such as Acute Physiology and Chronic Health Evaluation (APACHE II, IV) and…

Machine Learning · Computer Science 2023-08-11 Qizhang Feng , Jiayi Yuan , Forhan Bin Emdad , Karim Hanna , Xia Hu , Zhe He

The midline related pathological image features are crucial for evaluating the severity of brain compression caused by stroke or traumatic brain injury (TBI). The automated midline delineation not only improves the assessment and clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-02-28 Shen Wang , Kongming Liang , Chengwei Pan , Chuyang Ye , Xiuli Li , Feng Liu , Yizhou Yu , Yizhou Wang

Graph neural networks (GNNs) have been developed to model the relationship between regions of interest (ROIs) in brains and have shown significant improvement in detecting brain diseases. However, most of these frameworks do not consider…

Machine Learning · Computer Science 2025-06-23 Falih Gozi Febrinanto , Adonia Simango , Chengpei Xu , Jingjing Zhou , Jiangang Ma , Sonika Tyagi , Feng Xia

Time is a fundamental factor during stroke treatments. A fast, automatic approach that segments the ischemic regions helps treatment decisions. In clinical use today, a set of color-coded parametric maps generated from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Luca Tomasetti , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Stroke is a leading cause of neurological injury characterized by impairments in multiple neurological domains including cognition, language, sensory and motor functions. Clinical recovery in these domains is tracked using a wide range of…

Quantitative Methods · Quantitative Biology 2021-10-01 Sanjukta Krishnagopal , Keith Lohse , Robynne Braun

Objective: Modern medicine needs to shift from a wait and react, curative discipline to a preventative, interdisciplinary science aiming at providing personalised, systemic and precise treatment plans to patients. The aim of this work is to…

Machine Learning · Statistics 2020-09-18 Pietro Barbiero , Ramon Viñas Torné , Pietro Lió

This work considers the optimization of electrode positions in head imaging by electrical impedance tomography. The study is motivated by maximizing the sensitivity of electrode measurements to conductivity changes when monitoring the…

Numerical Analysis · Mathematics 2023-12-19 N. Hyvönen , A. Jääskeläinen , R. Maity , A. Vavilov

During the diagnosis of ischemic strokes, the Circle of Willis and its surrounding vessels are the arteries of interest. Their visualization in case of an acute stroke is often enabled by Computed Tomography Angiography (CTA). Still, the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Florian Thamm , Markus Jürgens , Oliver Taubmann , Aleksandra Thamm , Leonhard Rist , Hendrik Ditt , Andreas Maier

Whilst grading neurovascular abnormalities is critical for prompt surgical repair, no statistical markers are currently available for predicting the risk of adverse events, such as stroke, and the overall resilience of a network to vascular…

Quantitative Methods · Quantitative Biology 2019-10-30 Stefano Moriconi , Rafael Rehwald , Maria A. Zuluaga , H. Rolf Jäger , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso

Despite the recent success of reconciling spike-based coding with the error backpropagation algorithm, spiking neural networks are still mostly applied to tasks stemming from sensory processing, operating on traditional data structures like…

Neural and Evolutionary Computing · Computer Science 2023-08-25 Dominik Dold , Josep Soler Garrido

Understanding the connectivity in the brain is an important prerequisite for understanding how the brain processes information. In the Brain/MINDS project, a connectivity study on marmoset brains uses two-photon microscopy fluorescence…

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

Statistical Mechanics · Physics 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

Machine Learning · Statistics 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson
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