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We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

MiRNAs, due to their role in gene regulation, have paved a new pathway for pharmacology, focusing on drug development that targets miRNAs. However, traditional wet lab experiments are limited by efficiency and cost constraints, making it…

Machine Learning · Computer Science 2025-12-08 Ziqi Zhang

Goal: We consider the problem of automatically grouping logs of runs that failed for the same underlying reasons, so that they can be treated more effectively, and investigate the following questions: (1) Does an approach developed to…

Software Engineering · Computer Science 2020-09-08 Carl Martin Rosenberg , Leon Moonen

Mammography, the current standard for breast cancer screening, has reduced sensitivity in women with dense breast tissue, contributing to missed or delayed diagnoses. Thermalytix, an AI-based thermal imaging modality, captures functional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Siva Teja Kakileti , Bharath Govindaraju , Sudhakar Sampangi , Geetha Manjunath

In high-energy particle physics, complex Monte Carlo (MC) simulations are needed to compare theory predictions to measurable quantities. Many and large MC samples are needed to be generated to take into account all the systematics.…

High Energy Physics - Experiment · Physics 2022-11-15 Valentina Guglielmi

Medical segmentation is performed to determine the bounds of regions of interest (ROI) prior to surgery. By allowing the study of growth, structure, and behaviour of the ROI in the planning phase, critical information can be obtained,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Bao Nguyen , Adam Feldman , Sarath Bethapudi , Andrew Jennings , Chris G. Willcocks

We consider the problem of clustering grouped data for which the observations may include group-specific variables in addition to the variables that are shared across groups. This type of data is common in cancer genomics where the…

Methodology · Statistics 2025-09-30 Arhit Chakrabarti , Yang Ni , Debdeep Pati , Bani K. Mallick

Density matrix embedding theory (DMET) provides a theoretical framework to treat finite fragments in the presence of a surrounding molecular or bulk environment, even when there is significant correlation or entanglement between the two. In…

Chemical Physics · Physics 2016-11-29 Sebastian Wouters , Carlos A. Jiménez-Hoyos , Qiming Sun , Garnet Kin-Lic Chan

Accurate segmentation of brain tumors from 3D multimodal MRI is vital for diagnosis and treatment planning across diverse brain tumors. This paper addresses the challenges posed by the BraTS 2023, presenting a unified transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Ramy A. Zeineldin , Franziska Mathis-Ullrich

Deep learning (DL) techniques have shown unprecedented success when applied to images, waveforms, and text. Generally, when the sample size ($N$) is much bigger than the number of features ($d$), DL often outperforms other machine learning…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Thanh Hai Nguyen , Edi Prifti , Yann Chevaleyre , Nataliya Sokolovska , Jean-Daniel Zucker

This work aims to characterise renal tumour microstructure using diffusion MRI (dMRI); via the Vascular, Extracellular and Restricted Diffusion for Cytometry in Tumours (VERDICT)-MRI framework with self-supervised learning. Comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Snigdha Sen , Lorna Smith , Lucy Caselton , Joey Clemente , Maxine Tran , Shonit Punwani , David Atkinson , Richard L Hesketh , Eleftheria Panagiotaki

DNA methylation is a well-studied genetic modification that regulates gene transcription of Eukaryotes. Its alternations have been recognized as a significant component of cancer development. In this study, we use the DNA methylation 450k…

Tissues and Organs · Quantitative Biology 2021-01-05 Shen Jia , Yulin Zhang , Yiming Mao , Jiawei Gao , Yixuan Chen , Yuxuan Jiang , Haochen Luo , Kebo Lv , Jionglong Su

Tabular datasets play a crucial role in various applications. Thus, developing efficient, effective, and widely compatible prediction algorithms for tabular data is important. Currently, two prominent model types, Gradient Boosted Decision…

Machine Learning · Computer Science 2024-07-16 Jiahuan Yan , Jintai Chen , Qianxing Wang , Danny Z. Chen , Jian Wu

Object detection, segmentation and classification are three common tasks in medical image analysis. Multi-task deep learning (MTL) tackles these three tasks jointly, which provides several advantages saving computing time and resources and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-06 Fei Gao , Hyunsoo Yoon , Teresa Wu , Xianghua Chu

Polymer architecture plays critical roles in both bulk rheological properties and microscale macromolecular dynamics in entangled polymer solutions and composites. Ring polymers, in particular, have been the topic of much debate due to the…

Soft Condensed Matter · Physics 2022-02-07 Pawan Khanal , Karthik R Peddireddy , Juexin Marfai , Ryan McGorty , Rae M Robertson-Anderson

Breast cancer is the second most common type of cancer in women in Canada and the United States, representing over 25\% of all new female cancer cases. As such, there has been immense research and progress on improving screening and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Chi-en Amy Tai , Hayden Gunraj , Nedim Hodzic , Nic Flanagan , Ali Sabri , Alexander Wong

Dataset distillation compresses large training sets into compact synthetic datasets while preserving downstream performance. As modern systems increasingly operate on paired vision-language inputs, multimodal distillation must preserve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jongoh Jeong , Hoyong Kwon , Minseok Kim , Kuk-Jin Yoon

In this paper, we propose a novel Joint framework for Deep Multi-view Clustering (DMJC), where multiple deep embedded features, multi-view fusion mechanism and clustering assignments can be learned simultaneously. Our key idea is that the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-26 Bingqian Lin , Yuan Xie , Yanyun Qu , Cuihua Li , Xiaodan Liang

We apply deep learning (DL) on Magnetic resonance spectroscopy (MRS) data for the task of brain tumor detection. Medical applications often suffer from data scarcity and corruption by noise. Both of these problems are prominent in our data…

Machine Learning · Computer Science 2021-12-17 Diyuan Lu , Gerhard Kurz , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos