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Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

Spectral clustering is a popular clustering method. It first maps data into the spectral embedding space and then uses Kmeans to find clusters. However, the two decoupled steps prohibit joint optimization for the optimal solution. In…

Machine Learning · Computer Science 2024-12-17 Wengang Guo , Wei Ye

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

This paper seeks to address the dense labeling problems where a significant fraction of the dataset can be pruned without sacrificing much accuracy. We observe that, on standard medical image segmentation benchmarks, the loss gradient…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Yongkang He , Mingjin Chen , Zhijing Yang , Yongyi Lu

Dataset distillation (DD) has emerged as a widely adopted technique for crafting a synthetic dataset that captures the essential information of a training dataset, facilitating the training of accurate neural models. Its applications span…

Machine Learning · Computer Science 2025-02-04 Saeed Vahidian , Mingyu Wang , Jianyang Gu , Vyacheslav Kungurtsev , Wei Jiang , Yiran Chen

Deep clustering is a deep neural network-based speech separation algorithm that first trains the mixed component of signals with high-dimensional embeddings, and then uses a clustering algorithm to separate each mixture of sources. In this…

Audio and Speech Processing · Electrical Eng. & Systems 2019-01-16 Soyeon Choe , Soo-Whan Chung , Youna Ji , Hong-Goo Kang

Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck that…

Quantitative Methods · Quantitative Biology 2020-07-20 Parth Patel , Kalpdrum Passi , Chakresh Kumar Jain

How do the neural networks distinguish two images? It is of critical importance to understand the matching mechanism of deep models for developing reliable intelligent systems for many risky visual applications such as surveillance and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Wenliang Zhao , Yongming Rao , Ziyi Wang , Jiwen Lu , Jie Zhou

Accurate segmentation of the ventricles from cardiac magnetic resonance images (CMRIs) is crucial for enhancing the diagnosis and analysis of heart conditions. Deep learning-based segmentation methods have recently garnered significant…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Hong Zheng , Yucheng Chen , Nan Mu , Xiaoning Li

Research on the localization of the genetic basis associated with diseases or traits has been widely conducted in the last a few decades. Scan methods have been developed for region-based analysis in whole-genome association studies,…

Methodology · Statistics 2024-10-31 Wei Zhang , Fan Wang , Fang Yao

The integration of machine learning in magnetic resonance imaging (MRI), specifically in neuroimaging, is proving to be incredibly effective, leading to better diagnostic accuracy, accelerated image analysis, and data-driven insights, which…

One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Apurva Pandya , Catherine Samuel , Nisargkumar Patel , Vaibhavkumar Patel , Thangarajah Akilan

RNA function is tied to secondary structure, operating through dynamic and heterogeneous structural ensembles. While current analysis tools typically output single static structures or averaged contact maps, chemical probing methods like…

Biomolecules · Quantitative Biology 2026-05-20 Giuseppe Sacco , Jianhui Li , Redmond P. Smyth , Guido Sanguinetti , Giovanni Bussi

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

The joint utilization of diverse data sources for medical imaging segmentation has emerged as a crucial area of research, aiming to address challenges such as data heterogeneity, domain shift, and data quality discrepancies. Integrating…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Eddardaa B. Loussaief , Mohammed Ayad , Domenc Puig , Hatem A. Rashwan

Motivation: Methods are needed to test pre-defined genomic regions such as promoters for differential methylation in genome-wide association studies, where the number of samples is limited and the data have large amounts of measurement…

Genomics · Quantitative Biology 2014-07-25 Duchwan Ryu , Hongyan Xu , Varghese George , Shaoyong Su , Xiaoling Wang , Huidong Shi , Robert H. Podolsky

Clustering multidimensional points is a fundamental data mining task, with applications in many fields, such as astronomy, neuroscience, bioinformatics, and computer vision. The goal of clustering algorithms is to group similar objects…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-22 Yihao Huang , Shangdi Yu , Julian Shun

A central problem in machine learning and pattern recognition is the process of recognizing the most important features. In this paper, we provide a new feature selection method (DRPT) that consists of first removing the irrelevant features…

Machine Learning · Computer Science 2021-05-19 Majid Afshar , Hamid Usefi

Pancreatic ductal adenocarcinoma (PDAC) segmentation on contrast-enhanced CT is inherently ambiguous: inter-rater disagreement among experts reflects genuine uncertainty rather than annotation noise. Standard deep learning approaches assume…

Machine Learning · Computer Science 2026-05-19 Tristan Kirscher , Alexandra Ertl , Klaus Maier-Hein , Xavier Coubez , Philippe Meyer , Sylvain Faisan