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A long-running goal of the clinical NLP community is the extraction of important variables trapped in clinical notes. However, roadblocks have included dataset shift from the general domain and a lack of public clinical corpora and…

Computation and Language · Computer Science 2022-12-01 Monica Agrawal , Stefan Hegselmann , Hunter Lang , Yoon Kim , David Sontag

This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four…

Computation and Language · Computer Science 2025-02-18 Shuqi Yang , Mingrui Jing , Shuai Wang , Jiaxin Kou , Manfei Shi , Weijie Xing , Yan Hu , Zheng Zhu

Medication Extraction and Mining play an important role in healthcare NLP research due to its practical applications in hospital settings, such as their mapping into standard clinical knowledge bases (SNOMED-CT, BNF, etc.). In this work, we…

Computation and Language · Computer Science 2024-12-31 Pablo Romero , Lifeng Han , Goran Nenadic

Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

Computation and Language · Computer Science 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace

Background: The potential of large language models (LLMs) to automate and support pharmacoepidemiologic study design is an emerging area of interest, yet their reliability remains insufficiently characterized. General-purpose LLMs often…

Computation and Language · Computer Science 2026-04-21 Xinyao Zhang , Nicole Sonne Heckmann , Manuela Del Castillo Suero , Francesco Paolo Speca , Maurizio Sessa

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

One of the most common solutions adopted by software researchers to address code generation is by training Large Language Models (LLMs) on massive amounts of source code. Although a number of studies have shown that LLMs have been…

Software Engineering · Computer Science 2023-08-25 Daniel Rodriguez-Cardenas , David N. Palacio , Dipin Khati , Henry Burke , Denys Poshyvanyk

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

In acupuncture therapy, the accurate location of acupoints is essential for its effectiveness. The advanced language understanding capabilities of large language models (LLMs) like Generative Pre-trained Transformers (GPT) present a…

Computation and Language · Computer Science 2024-09-10 Yiming Li , Xueqing Peng , Jianfu Li , Xu Zuo , Suyuan Peng , Donghong Pei , Cui Tao , Hua Xu , Na Hong

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Electronic Health Records are large repositories of valuable clinical data, with a significant portion stored in unstructured text format. This textual data includes clinical events (e.g., disorders, symptoms, findings, medications and…

Computation and Language · Computer Science 2024-09-02 Shubham Agarwal , Thomas Searle , Mart Ratas , Anthony Shek , James Teo , Richard Dobson

Genes, proteins and other biological entities influence one another via causal molecular networks. Causal relationships in such networks are mediated by complex and diverse mechanisms, through latent variables, and are often specific to…

Machine Learning · Computer Science 2025-03-07 Izzy Newsham , Luka Kovačević , Richard Moulange , Nan Rosemary Ke , Sach Mukherjee

Causal inference is one of the hallmarks of human intelligence. While the field of CausalNLP has attracted much interest in the recent years, existing causal inference datasets in NLP primarily rely on discovering causality from empirical…

Computation and Language · Computer Science 2024-04-18 Zhijing Jin , Jiarui Liu , Zhiheng Lyu , Spencer Poff , Mrinmaya Sachan , Rada Mihalcea , Mona Diab , Bernhard Schölkopf

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in…

Computation and Language · Computer Science 2023-06-19 Guangyu Wang , Guoxing Yang , Zongxin Du , Longjun Fan , Xiaohu Li

Over the past decade, extensive research efforts have been dedicated to the extraction of information from textual process descriptions. Despite the remarkable progress witnessed in natural language processing (NLP), information extraction…

Computation and Language · Computer Science 2024-07-29 Julian Neuberger , Lars Ackermann , Han van der Aa , Stefan Jablonski

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi
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