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$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

Background: Machine learning methods for clinical named entity recognition and entity normalization systems can utilize both labeled corpora and Knowledge Graphs (KGs) for learning. However, infrequently occurring concepts may have few…

Computation and Language · Computer Science 2024-10-11 Kuleen Sasse , Shinjitha Vadlakonda , Richard E. Kennedy , John D. Osborne

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Coronary angiography (CAG) reports contain clinically relevant physiological measurements, yet this information is typically in the form of unstructured natural language, limiting its use in research. We investigate the use of Large…

Computation and Language · Computer Science 2026-04-16 Sofia Morgado , Filipa Valdeira , Niklas Sander , Diogo Ferreira , Marta Vilela , Miguel Menezes , Cláudia Soares

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Large Language Models (LLMs) have demonstrated impressive performance in biomedical relation extraction, even in zero-shot scenarios. However, evaluating LLMs in this task remains challenging due to their ability to generate human-like…

Computation and Language · Computer Science 2025-06-03 Md Tahmid Rahman Laskar , Israt Jahan , Elham Dolatabadi , Chun Peng , Enamul Hoque , Jimmy Huang

Biomedical triple extraction systems aim to automatically extract biomedical entities and relations between entities. The exploration of applying large language models (LLM) to triple extraction is still relatively unexplored. In this work,…

Computation and Language · Computer Science 2024-04-30 Mingchen Li , Huixue Zhou , Rui Zhang

Developing the required technology to assist medical experts in their everyday activities is currently a hot topic in the Artificial Intelligence research field. Thus, a number of large language models (LLMs) and automated benchmarks have…

Computation and Language · Computer Science 2023-12-04 Iakes Goenaga , Aitziber Atutxa , Koldo Gojenola , Maite Oronoz , Rodrigo Agerri

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Purpose: This study aims to evaluate the effectiveness of large language models (LLMs) in automating disease annotation of CT radiology reports. We compare a rule-based algorithm (RBA), RadBERT, and three lightweight open-weight LLMs for…

With the emergence of Transformer architectures and their powerful understanding of textual data, a new horizon has opened up to predict the molecular properties based on text description. While SMILES are the most common form of…

Chemical Physics · Physics 2023-10-11 Suryanarayanan Balaji , Rishikesh Magar , Yayati Jadhav , Amir Barati Farimani

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Several biomedical language models have already been developed for clinical language inference. However, these models typically utilize general vocabularies and are trained on relatively small clinical corpora. We sought to evaluate the…

Computation and Language · Computer Science 2022-10-14 Madhumita Sushil , Dana Ludwig , Atul J. Butte , Vivek A. Rudrapatna

Large Language Models (LLMs) offer natural language explanations as an alternative to feature attribution methods for model interpretability. However, despite their plausibility, they may not reflect the model's true reasoning faithfully.…

Computation and Language · Computer Science 2025-12-29 Kerem Zaman , Shashank Srivastava

We test whether NLP datasets created with Large Language Models (LLMs) contain annotation artifacts and social biases like NLP datasets elicited from crowd-source workers. We recreate a portion of the Stanford Natural Language Inference…

Computation and Language · Computer Science 2025-03-10 Grace Proebsting , Adam Poliak

Traditional topic models often struggle with contextual nuances and fail to adequately handle polysemy and rare words. This limitation typically results in topics that lack coherence and quality. Large Language Models (LLMs) can mitigate…

Computation and Language · Computer Science 2025-05-13 Hajar Sakai , Sarah S. Lam

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

Machine Learning · Computer Science 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu

Large Language Models (LLMs), such as GPT-4 and Llama 2, show remarkable proficiency in a wide range of natural language processing (NLP) tasks. Despite their effectiveness, the high costs associated with their use pose a challenge. We…

Computation and Language · Computer Science 2024-03-26 Bálint Csanády , Lajos Muzsai , Péter Vedres , Zoltán Nádasdy , András Lukács

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer…

Computation and Language · Computer Science 2024-03-20 Cheng Peng , Zehao Yu , Kaleb E Smith , Wei-Hsuan Lo-Ciganic , Jiang Bian , Yonghui Wu

In this paper, we consider the process of transforming causal domain knowledge into a representation that aligns more closely with guidelines from causal data science. To this end, we introduce two novel tasks related to distilling causal…

Computation and Language · Computer Science 2024-11-26 Houssam Razouk , Leonie Benischke , Georg Niess , Roman Kern
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