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In clinical trials, studies often present longitudinal data or clustered data. These studies are commonly analyzed using linear mixed models (LMMs), usually considering Gaussian assumptions for random effect and error terms. Recently,…

Methodology · Statistics 2021-09-28 Fernanda L. Schumacher , Larissa A. Matos , Celso R. B. Cabral

Contemporary cardiovascular management involves complex consideration and integration of multimodal cardiac datasets, where each modality provides distinct but complementary physiological characteristics. While the effective integration of…

Constant potential methods (CPM) enable computationally efficient simulations of the solid-liquid interface at conducting electrodes in molecular dynamics (MD). They have been successfully used, for example, to realistically model the…

Chemical Physics · Physics 2022-07-29 Ludwig J. V. Ahrens-Iwers , Mathijs Janssen , Shern R. Tee , Robert H. Meißner

Imaging modalities such as Computed Tomography (CT) and Positron Emission Tomography (PET) are key in cancer detection, inspiring Deep Neural Networks (DNN) models that merge these scans for tumor segmentation. When both CT and PET scans…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Nada Saadi , Numan Saeed , Mohammad Yaqub , Karthik Nandakumar

Over the course of the past two decades, a substantial body of research has substantiated the viability of utilising cardiac signals as a biometric modality. This paper presents a novel approach for patient identification in healthcare…

Machine Learning · Computer Science 2024-11-27 Caterina Fuster-Barceló , Carmen Cámara , Pedro Peris-López

In this work we develop a simple equivalent circuit model (ECM) that predicts the spectral response of a lumped-element loaded single patterned layer reflective metasurface. The proposed ECM maintains accuracy across varying design…

In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac behavior. A popular and efficient technique is to use an electrical circuit analogy,…

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highlighting the critical need for efficient and accurate diagnostic tools. Electrocardiograms (ECGs) are indispensable in diagnosing various heart conditions;…

Signal Processing · Electrical Eng. & Systems 2025-04-24 Lei Kang , Xuanshuo Fu , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

In the framework of accurate and efficient segregated schemes for 3D cardiac electromechanics and 0D cardiovascular models, we propose here a novel numerical approach to address the coupled 3D-0D problem introduced in Part I of this…

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Domain-specific text embeddings are critical for clinical natural language processing, yet systematic comparisons across model architectures remain limited. This study evaluates ten transformer-based embedding models adapted for cardiology…

Computation and Language · Computer Science 2025-11-26 Richard J. Young , Alice M. Matthews

A central problem in biomechanical studies of personalised human left ventricular (LV) modelling is estimating the material properties and biophysical parameters from in-vivo clinical measurements in a time frame suitable for use within a…

Applications · Statistics 2019-05-16 Vinny Davies , Umberto Noè , Alan Lazarus , Hao Gao , Benn Macdonald , Colin Berry , Xiaoyu Luo , Dirk Husmeier

Low-dose chest computed tomography (LDCT) captures pulmonary and cardiac structures in a single scan, enabling joint assessment of lung and cardiovascular health. Existing approaches typically model these domains independently and do not…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yifei Zhang , Jiashuo Zhang , Mojtaba Safari , Xiaofeng Yang , Liang Zhao

Many people are currently suffering from heart diseases that can lead to untimely death. The most common heart abnormality is arrhythmia, which is simply irregular beating of the heart. A prediction system for the early intervention and…

Signal Processing · Electrical Eng. & Systems 2018-06-22 Aboul Ella Hassanien , Moataz Kilany , Essam H. Houssein

Extreme Learning Machines (ELM) provide a fast alternative to traditional gradient-based learning in neural networks, offering rapid training and robust generalization capabilities. Its theoretical basis shows its universal approximation…

Machine Learning · Computer Science 2024-06-27 Ergun Biçici

Background. Despite the routine prescription of rate control therapy for atrial fibrillation (AF), clinical evidence demonstrating a heart rate target is lacking. Aim of the present study was to run a mathematical model simulating AF…

Chronic kidney disease (CKD) is a global health challenge characterized by progressive kidney function decline, often culminating in end-stage kidney disease (ESKD) and increased mortality. To address the limitations such as the extended…

Methodology · Statistics 2025-04-11 Tuo Wang , Yu Du

We develop a remote patient monitoring (RPM) service architecture, which has two tiers of monitoring: ordinary and intensive. The patient's health state improves or worsens in each time period according to certain probabilities, which…

Systems and Control · Electrical Eng. & Systems 2024-09-20 Siddharth Chandak , Isha Thapa , Nicholas Bambos , David Scheinker

Cardiopulmonary resuscitation (CPR) is one of the most critical emergency interventions for sudden cardiac arrest. In this paper, a robust sinusoidal model-fitting method based on a Evolution Strategy inspired algorithm for CPR quality…

Neural and Evolutionary Computing · Computer Science 2020-10-27 Christian Lins , Björn Friedrich , Andreas Hein , Sebastian Fudickar