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Chemical reactions are the fundamental building blocks of drug design and organic chemistry research. In recent years, there has been a growing need for a large-scale deep-learning framework that can efficiently capture the basic rules of…

Machine Learning · Computer Science 2024-03-08 Bo Qiang , Yiran Zhou , Yuheng Ding , Ningfeng Liu , Song Song , Liangren Zhang , Bo Huang , Zhenming Liu

The performance of modern lithium-sulfur (Li/S) battery systems critically depends on the electrolyte and solvent compositions. For fundamental molecular insights and rational guidance of experimental developments, efficient and…

Molecular representation learning plays a crucial role in advancing applications such as drug discovery and material design. Existing work leverages 2D and 3D modalities of molecular information for pre-training, aiming to capture…

Machine Learning · Computer Science 2025-10-09 Tengwei Song , Min Wu , Yuan Fang

Fast and reliable validation of novel designs in complex physical systems such as batteries is critical to accelerating technological innovation. However, battery research and development remain bottlenecked by the prohibitively high time…

Machine Learning · Computer Science 2025-09-26 Jiawei Zhang , Yifei Zhang , Baozhao Yi , Yao Ren , Qi Jiao , Hanyu Bai , Weiran Jiang , Ziyou Song

Molecule inverse folding has been a long-standing challenge in chemistry and biology, with the potential to revolutionize drug discovery and material science. Despite specified models have been proposed for different small- or…

Artificial Intelligence · Computer Science 2024-05-30 Zhangyang Gao , Jue Wang , Cheng Tan , Lirong Wu , Yufei Huang , Siyuan Li , Zhirui Ye , Stan Z. Li

Advanced computational methods are being actively sought for addressing the challenges associated with discovery and development of new combinatorial material such as formulations. A widely adopted approach involves domain informed…

Latent diffusion models (LDM) have revolutionized text-to-image generation, leading to the proliferation of various advanced models and diverse downstream applications. However, despite these significant advancements, current diffusion…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Jiacheng Zhang , Jie Wu , Yuxi Ren , Xin Xia , Huafeng Kuang , Pan Xie , Jiashi Li , Xuefeng Xiao , Weilin Huang , Shilei Wen , Lean Fu , Guanbin Li

Machine learning (ML) plays an important role in quantum chemistry, providing fast-to-evaluate predictive models for various properties of molecules. However, most existing ML models for molecular electronic properties use density…

Chemical Physics · Physics 2024-06-26 Hao Tang , Brian Xiao , Wenhao He , Pero Subasic , Avetik R. Harutyunyan , Yao Wang , Fang Liu , Haowei Xu , Ju Li

Accurate forecasting of battery health indicators, including remaining capacity and lifetime, is of paramount importance for ensuring the reliability, safety, and operational efficiency of applications such as electric vehicles and large…

Signal Processing · Electrical Eng. & Systems 2026-05-29 Athanasios Koukosias , Vasileios Tzanidakis , Sotiris Athanasiou , Kostas Kolomvatsos

Battery management systems may rely on mathematical models to provide higher performance than standard charging protocols. Electrochemical models allow us to capture the phenomena occurring inside a lithium-ion cell and therefore, could be…

Computational Engineering, Finance, and Science · Computer Science 2020-05-12 Andrea Pozzi , Xiangzhong Xie , Davide M Raimondo , René Schenkendorf

Federated learning (FL) is a promising approach for enhancing data privacy preservation, particularly for authentication systems. However, limited round communications, scarce representation, and scalability pose significant challenges to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Hansol Kim , Youngjun Kwak , Minyoung Jung , Jinho Shin , Youngsung Kim , Changick Kim

In-context learning (ICL) enhances the reasoning abilities of Large Language Models (LLMs) by prepending a few demonstrations. It motivates researchers to introduce more examples to provide additional contextual information for the…

Computation and Language · Computer Science 2025-05-27 Jun Gao , Qi Lv , Zili Wang , Tianxiang Wu , Ziqiang Cao , Wenjie Li

The optimization of the electrodes manufacturing process constitutes one of the most critical steps to ensure high-quality Lithium-Ion Battery (LIB) cells, in particular for automotive applications. Because LIB electrode manufacturing is a…

Process optimization in chemical engineering may be hindered by the limited availability of reliable thermodynamic data for fluid mixtures. Remarkable progress is being made in predicting thermodynamic mixture properties by machine learning…

Computational Engineering, Finance, and Science · Computer Science 2025-10-14 Martin Bubel , Tobias Seidel , Michael Bortz

Deep learning models tend to forget their earlier knowledge while incrementally learning new tasks. This behavior emerges because the parameter updates optimized for the new tasks may not align well with the updates suitable for older…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 K J Joseph , Salman Khan , Fahad Shahbaz Khan , Rao Muhammad Anwer , Vineeth N Balasubramanian

Mathematical modeling of lithium-ion batteries (LiBs) is a primary challenge in advanced battery management. This paper proposes two new frameworks to integrate physics-based models with machine learning to achieve high-precision modeling…

Computational Engineering, Finance, and Science · Computer Science 2024-08-23 Hao Tu , Scott Moura , Yebin Wang , Huazhen Fang

Agent-based modeling (ABM) is a powerful tool for understanding self-organizing biological systems, but it is computationally intensive and often not analytically tractable. Equation learning (EQL) methods can derive continuum models from…

In this study, we present a sophisticated hybrid machine-learning framework that significantly improves the accuracy of predicting hydrogen storage capacities in metal hydrides. This is a critical challenge due to the scarcity of…

Materials Science · Physics 2024-08-29 Satadeep Bhattacharjee , Pritam Das , Swetarekha Ram , Seung-Cheol Lee

Universal machine learning force fields (UMLFFs) promise to revolutionize materials science by enabling rapid atomistic simulations across the periodic table. However, their evaluation has been limited to computational benchmarks that may…

Pre-training large language models on genomic sequences is a powerful approach for learning biologically meaningful representations. Masked language modeling (MLM) methods, such as DNABERT and Nucleotide Transformer (NT), achieve strong…

Genomics · Quantitative Biology 2025-08-20 Ke Ding , Brian Parker , Jiayu Wen