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Simulations are vital for understanding and predicting the evolution of complex molecular systems. However, despite advances in algorithms and special purpose hardware, accessing the timescales necessary to capture the structural evolution…

Computational Physics · Physics 2021-02-18 Pantelis R. Vlachas , Julija Zavadlav , Matej Praprotnik , Petros Koumoutsakos

Universal machine learning interatomic potentials (UMLIPs) offer accuracy close to first-principles calculations at a fraction of the cost, showing significant potential for large-scale material simulations. However, the fragmented UMLIPs…

Materials Science · Physics 2026-03-17 Yanjin Xiang , Yihan Nie , Yunzhi Gao , Haidi Wang , Wei Hu

Geometric representation-conditioned molecule generation provides an effective paradigm that decouples molecule representation modeling from structure generation. By decoupling molecule generation into two stages-first generating a…

Machine Learning · Computer Science 2026-05-11 Shaoheng Yan , Zian Li , Cai Zhou , Qiaojing Huang , Kai Liu , Muhan Zhang

Molecular Field-Coupled Nanocomputing (MolFCN) is a promising beyond-CMOS paradigm in which information is propagated electrostatically rather than through charge transport, enabling ultra-low-power logic. Identifying molecules with stable…

The development of machine learning (ML) methods has made quantum chemistry (QC) calculations more accessible by reducing the compute cost incurred in conventional QC methods. This has since been translated into the overhead cost of…

Chemical Physics · Physics 2025-03-26 Vivin Vinod , Peter Zaspel

In this paper, we demonstrate a computationally efficient new approach based on deep learning (DL) techniques for analysis, design, and optimization of electromagnetic (EM) nanostructures. We use the strong correlation among features of a…

Machine Learning · Computer Science 2020-02-13 Yashar Kiarashinejad , Sajjad Abdollahramezani , Ali Adibi

We present Unified Latent Dynamics (ULD), a novel reinforcement learning algorithm that unifies the efficiency of model-free methods with the representational strengths of model-based approaches, without incurring planning overhead. By…

Machine Learning · Computer Science 2026-02-16 Jashaswimalya Acharjee , Balaraman Ravindran

Simulating electrified metal/water interfaces with explicit solvent under constant potential is essential for understanding electrochemical processes, yet remains prohibitively expensive with ab initio methods. We present TRECI, a…

An important objective of designing lithium-ion rechargeable battery cells is to maximize their rate performance without compromising the energy density, which is mainly achieved through computationally expensive numerical simulations at…

Materials Science · Physics 2020-05-05 Fan Wang , Ming Tang

Recent advancements in NLP have witnessed the groundbreaking impact of pretrained models, yielding impressive outcomes across various tasks. This study seeks to extend the power of pretraining methodologies to facilitating the prediction…

Machine Learning · Computer Science 2024-03-14 Yazheng Yang , Yuqi Wang , Guang Liu , Ledell Wu , Qi Liu

Machine learning (ML) techniques have rapidly found applications in many domains of materials chemistry and physics where large data sets are available. Aiming to accelerate the discovery of materials for battery applications, in this work,…

Materials Science · Physics 2019-05-24 Rajendra P. Joshi , Jesse Eickholt , Liling Li , Marco Fornari , Veronica Barone , Juan E. Peralta

The biological functions of proteins often depend on dynamic structural ensembles. In this work, we develop a flow-based generative modeling approach for learning and sampling the conformational landscapes of proteins. We repurpose highly…

Biomolecules · Quantitative Biology 2024-09-04 Bowen Jing , Bonnie Berger , Tommi Jaakkola

Recent advances in Entity Resolution (ER) have leveraged Large Language Models (LLMs), achieving strong performance but at the cost of substantial computational resources or high financial overhead. Existing LLM-based ER approaches operate…

Databases · Computer Science 2026-02-06 Alexandros Zeakis , George Papadakis , Dimitrios Skoutas , Manolis Koubarakis

AI inference at the edge is becoming increasingly common for low-latency services. However, edge environments are power- and resource-constrained, and susceptible to failures. Conventional failure resilience approaches, such as cloud…

Active learning (AL) accelerates scientific discovery by prioritizing the most informative experiments, but traditional machine learning (ML) models used in AL suffer from cold-start limitations and domain-specific feature engineering,…

Machine Learning · Computer Science 2025-12-05 Hongchen Wang , Rafael Espinosa Castañeda , Jay R. Werber , Yao Fehlis , Edward Kim , Jason Hattrick-Simpers

Recent cross-lingual cross-modal works attempt to extend Vision-Language Pre-training (VLP) models to non-English inputs and achieve impressive performance. However, these models focus only on understanding tasks utilizing encoder-only…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Bin Shan , Yaqian Han , Weichong Yin , Shuohuan Wang , Yu Sun , Hao Tian , Hua Wu , Haifeng Wang

In the global drive toward carbon neutrality, deeply coordinated smart energy systems underpin industrial transformation. However, the interdisciplinary, fragmented, and fast-evolving expertise in this domain prevents general-purpose LLMs,…

Artificial Intelligence · Computer Science 2026-02-02 Haoyu Jiang , Fanjie Zeng , Boan Qu , Xiaojie Lin , Wei Zhong

Accurate characterization of the equilibrium distributions of complex molecular systems and their dependence on environmental factors such as temperature is essential for understanding thermodynamic properties and transition mechanisms.…

Machine Learning · Computer Science 2025-07-08 Yunrui Qiu , Richard John , Lukas Herron , Pratyush Tiwary

The quest for accurate prediction of drug molecule properties poses a fundamental challenge in the realm of Artificial Intelligence Drug Discovery (AIDD). An effective representation of drug molecules emerges as a pivotal component in this…

Machine Learning · Computer Science 2024-04-22 Zhuoyuan Wang , Jiacong Mi , Shan Lu , Jieyue He

Entropy minimization (EM) trains the model to concentrate even more probability mass on its most confident outputs. We show that this simple objective alone, without any labeled data, can substantially improve large language models' (LLMs)…

Machine Learning · Computer Science 2025-05-22 Shivam Agarwal , Zimin Zhang , Lifan Yuan , Jiawei Han , Hao Peng
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